Published Paper Details:

Chemotherapy, a cornerstone of cancer treatment, often comes with significant side effects due to its cytotoxic effects on both cancerous and healthy cells. Among the numerous cellular stressors induced by chemotherapy, oxidative stress plays a key role in the damage to healthy tissues. Antioxidants, such as magnesium and copper, have been proposed as potential adjuncts to reduce these adverse effects. Magnesium, a vital cofactor in many enzymatic processes, has demonstrated protective properties against oxidative damage, potentially mitigating chemotherapy-induced inflammation and cellular injury. Copper, an essential trace element, plays a dual role in cancer biology; while excessive copper may enhance tumor growth through angiogenesis and oxidative stress, maintaining optimal copper levels may support the body's antioxidant defenses. This paper explores the potential of magnesium and copper in cancer therapy, focusing on their ability to reduce oxidative stress and improve patient quality of life during chemotherapy. By understanding the balance of these elements, clinicians may be able to develop more effective and personalized therapeutic strategies to minimize chemotherapy's harmful side effects.