Published Paper Details:

Abstract: - Objective: - To formulate and evaluate multipurpose herbal cream using Neem, Turmeric and Tulsi extract to give anti-inflammatory, anti-fungal and anti-bacterial effect. Methods: - The cream was prepared by using cream base which is liquid paraffin, beeswax, methyl paraben, stearic acid, cetyl alcohol, glycerin, distilled water, Aloe vera gel, extracts of Neem, Turmeric and Tulsi. The cream was prepared by slab technique or extemporaneous method for mixing the cream in geometric manner to provide a smooth texture and for mixing of all ingredients properly. From using trituration method by mortar pestle, we have formulated NEM4, batch of our herbal cream. NEM4, batch were evaluated / test for different parameters like physical evaluation, irritancy, washability, pH determination, phase separation, spreadability, Greasiness, Homogeneity after observation in all over batches NEM4 batch was giving the best result. Results: - NEM1-NEM5, formulations, showed good appearance, almost neutral pH, no erythema, edema and redness on skin during irritancy study, easily washable, good spread ability and no phase separation. The formulations NEM4, were found stable at room temperature and it was giving best result. Conclusion: - By using Neem, Turmeric, Tulsi and Aloe-vera gel the herbal cream showed multipurpose effect such as anti-inflammatory, anti-fungal and anti-bacterial also all herbal ingredients were used to showed different significant activities. Based on the results we can say that formulations NEM4, were stable at room temperature and can be safely used on the skin.