Published Paper Details:

Transdermal drug delivery system falls under the control drug delivery category aiming to administer drug through the skin a pre determine and controlled rate over extended period. Transdermal drug delivery system have several advantages such as reduced dose frequency, avoiding first pass metabolism by entering direct into systemic circulation, Suitability for elderly patient who cannot take pharmaceuticals orally and ability to be self administer with fever side effect. Multiple drug administration has several disadvantages include cannot achieve high drug level in blood, long time adherence is difficult. This review cover general aspects like drug absorption pathways through skin, different factor affecting transdermal permeability, various types of transdermal patches, components of transdermal patches, evaluation parameter. Additionally therapeutic application of transdermal drug delivery system, moreover, the articles includes various advancements in the transdermal drug delivery system.