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Introduction: Respiratory health is a critical aspect of overall well-being, particularly among college students who may face various challenges affecting their lung function. This study investigates the effectiveness of spirometer interventions in improving lung function among college students, addressing a gap in the literature regarding respiratory health promotion strategies in this population. Given the rising prevalence of respiratory issues and the potential impact on academic performance and quality of life, understanding effective interventions is paramount. Objective and Aims: The primary objective of the study is to assess the effectiveness of spirometer interventions in improving lung function among college students. Specifically, the study aims to measure changes in chest expansion and breath-holding time following spirometer use and compare the efficacy of spirometer interventions with deep breathing exercises. By addressing these objectives, the study seeks to contribute to our understanding of effective respiratory health promotion strategies in college settings. The study is framed within the theoretical perspective of health behavior change, drawing on constructs from social cognitive theory and the trans theoretical model. These frameworks emphasize the importance of self-efficacy, outcome expectations, and stages of change in adopting and maintaining health behaviors. In the context of spirometer interventions, these theories provide insights into the psychological processes involved in behavior change related to respiratory health. Materials and Methods: A mixed-methods approach is employed, comprising quantitative measurements and qualitative interviews. The research methodology involves spirometer tests to assess chest expansion and breath-holding time, supplemented by participant feedback through qualitative interviews. The sample consists of college students aged 20 to 30 years, selected through random sampling techniques. Data analysis includes descriptive statistics, t-tests, and thematic analysis to explore quantitative and qualitative findings. Quantitative analysis reveals a significant increase in chest expansion and breath-holding time post-spirometer intervention, indicating improvements in lung function among participants. Qualitative insights highlight participant satisfaction with spirometer usability and perceived benefits. Comparative analysis with deep breathing exercises shows comparable effectiveness in promoting respiratory health. Results: Interpreting the findings within the theoretical framework of health behavior change, the study underscores the importance of self-efficacy and outcome expectations in adopting spirometer interventions. The results support the notion that spirometer usage can facilitate positive changes in lung function, aligning with theories of health behavior change. Implications for theory development include the integration of spirometer interventions into existing models of behavior change and the exploration of mechanisms underlying intervention effectiveness. Existing literature supports the theoretical framework by highlighting the effectiveness of respiratory interventions, such as spirometer usage and deep breathing exercises, in improving lung function and overall respiratory health. Studies have demonstrated the positive impact of these interventions on lung capacity, breath-holding time, and subjective measures of respiratory well-being among various populations, including college students. Conclusion: The study demonstrates the effectiveness of spirometer interventions in improving lung function among college students, offering insights into respiratory health promotion strategies in educational settings. The findings contribute to theory development by validating the role of self-efficacy and outcome expectations in adopting respiratory interventions. Future research should further explore the long-term effects of spirometer interventions and their potential applications in diverse populations. Recommendations: Potential areas for future research include longitudinal studies to assess the sustained impact of spirometer interventions on lung function and respiratory health outcomes. Additionally, investigating the effectiveness of tailored intervention approaches based on individual characteristics and stages of behavior change could enhance our understanding of respiratory health promotion strategies. Moreover, exploring the integration of technology, such as mobile spirometer applications, may offer innovative solutions for enhancing respiratory health behaviors among college students. Overall, spirometer interventions emerged as promising tools for promoting respiratory health among college students, warranting further research to explore their long-term effects and potential applications in diverse populations.