Published Paper Details:

Chronic Kidney Disease (CKD) is a progressive condition that poses significant public health challenges, affecting over 10% of the adult population worldwide. This study explores examining etiopathogenesis of CKD through the lens of Ayurveda, to facilatate a appropraite treatment regimen in an efficient patient care. CKD is characterized by a gradual decline in kidney function, typically marked by a decrease in glomerular filtration rate (GFR) and proteinuria. The absence of direct references to CKD in classical Ayurvedic texts necessitates an understanding of the disease through its related concepts--Nidan (aetiology), Lakshan (signs), and Samprapti (pathogenesis). CKD symptoms develop insidiously, with advanced stages presenting as dyspnoea, peripheral oedema, and fatigue. The study identifies prodromal symptoms and establishes clinical correlations with Ayurvedic concepts, enabling a comprehensive understanding of CKD's progression. Our analysis reveals that CKD corresponds to the vitiation of Meda (fat) and Rakta (blood) dhatus, influenced by unhealthy dietary habits and lifestyle choices, leading to the dysfunction of Mutravaha srotas (urinary channels). The pathogenesis involves imbalances in the three doshas (Vata, Pitta, and Kapha), with a notable predominance of Vata, causing srotorodha (obstruction of channels) and consequent renal impairment. This research emphasizes the importance of addressing dietary and lifestyle factors in managing CKD. Proposed Ayurvedic treatments focus on enhancing digestive fire, balancing doshas, promoting diuresis, and ensuring srotosodhana (cleansing of channels). By integrating Ayurvedic principles into contemporary medical frameworks, we aim to provide a holistic approach to CKD management, ultimately improving patient outcomes and quality of life.