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Paper Title
REVIEW ON HPLC METHOD DEVELOPMENT AND VALIDATION
Authors
Choudhari Pruthviraj Baban, Pavase Suraj, Kudale Shraddha, Khandagale Ravindra
Keywords
HPLC, method development, validation, accuracy, specificity
Abstract
This review outlines a plan for the methodical advancement of HPLC. One of the most powerful analytical chemistry technologies now in use is high performance liquid chromatography. Any liquid-soluble material can have its constituents separated, identified, and quantified by it. A number of chromatographic parameters, including as sample pretreatment, mobile phase selection, column selection, and detector selection, were examined in order to optimize the procedure. This article aims to discuss the process of developing, optimizing, and validating methods.The development of the HPLC method is influenced by the molecules' chemical structure, the synthetic pathway, solubility, polarity, pH and pKa values, and the activity of the functional groups, among other factors. The purpose of this essay was to review the development and validation of HPLC methods.
IJCRT's Publication Details
Unique Identification Number - IJCRT2410675
Paper ID - 271450
Page Number(s) - f808-f814
Pubished in - Volume 12 | Issue 10 | October 2024
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Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Choudhari Pruthviraj Baban, Pavase Suraj, Kudale Shraddha, Khandagale Ravindra, "REVIEW ON HPLC METHOD DEVELOPMENT AND VALIDATION", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.12, Issue 10, pp.f808-f814, October 2024, Available at :http://www.ijcrt.org/papers/IJCRT2410675.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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