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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
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Published Paper Details:
Paper Title
"Imeglimin : A Novel Therapeutic Approach Targeting the Core Mechanisms of Type 2 Diabetes"
Authors
Sakshi Manohar Kawade, Kaushal Arjun Thorat, Shubham Nandkishor Girge, Vaishnavi Chhagan Kardile, Vandana Popat Kolhe
Keywords
Imeglimin, Type 2 Diabetes Mellitus, Glycaemic Control, Antihyperglycemic Effects, ?-cell Apoptosis, Hepatic Gluconeogenesis, Muscle Glucose Uptake
Abstract
Imeglimin is a new chemical that is being developed to treat type 2 diabetes mellitus. It is the first drug in the "glimin" class of medications that reduce blood sugar. Its distinct mode of action targets the three primary pathophysiologic elements of type 2 diabetes: increased ?-cell apoptosis, excess hepatic gluconeogenesis, and decreased muscle tissue uptake of glucose. Imeglimin has been assessed in numerous preclinical and clinical trials to far, and the results have demonstrated that it has noteworthy antihyperglycemic effects, including statistically significant decreases in fasting plasma glucose, glycated hemoglobin, and other glycaemic indices. Hopefully in the near future, its efficaciousness along with an attractive tolerability profile may allow it to be used as a monotherapy or in conjunction with other types of antidiabetic medicines.
IJCRT's Publication Details
Unique Identification Number - IJCRT2409765
Paper ID - 269924
Page Number(s) - g854-g860
Pubished in - Volume 12 | Issue 9 | September 2024
DOI (Digital Object Identifier) -
Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Sakshi Manohar Kawade, Kaushal Arjun Thorat, Shubham Nandkishor Girge, Vaishnavi Chhagan Kardile, Vandana Popat Kolhe, ""Imeglimin : A Novel Therapeutic Approach Targeting the Core Mechanisms of Type 2 Diabetes"", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.12, Issue 9, pp.g854-g860, September 2024, Available at :http://www.ijcrt.org/papers/IJCRT2409765.pdf
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Volume 14 | Issue 4
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
ISSN and 7.97 Impact Factor Details
ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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