Published Paper Details:

Liver cirrhosis is a complex, progressive disease characterized by fibrosis and impaired liver function, resulting from a range of etiological factors. This comparative analysis explores the three primary causes of cirrhosis: viral hepatitis (primarily Hepatitis B and C), alcohol-related liver disease, and non-alcoholic fatty liver disease (NAFLD), a metabolic disorder linked to obesity and diabetes. By examining clinical presentations, biochemical markers, and histopathological features, the study delineates both overlapping and distinct pathways of liver damage in each condition. Key findings include the accelerated progression of cirrhosis in viral hepatitis, the direct hepatotoxic effects of alcohol, and the systemic metabolic dysfunction underlying NAFLD. The study highlights differences in prognosis, treatment options, and preventive strategies, emphasizing the need for early diagnosis and targeted interventions to manage the diverse etiologies of liver cirrhosis effectively. This research contributes to a more nuanced understanding of the disease, aiding in the development of personalized therapeutic approaches