Published Paper Details:

Oxidative stress is a result of variation in levels of antioxidants that act as protective shields. Lower levels of antioxidants lead to deterioration of healthy cells exposing them to reactive oxygen species, peroxyl radicals, peroxy nitrite, hydroxyl radicals, singlet oxygen and allied species. Many diseases associated with lack of antioxidants are Parkinson's and Alzheimer's, ischemic injury, cancer and premature ageing. Spirogyra majuscule found in Koppa of Chickmagaluru district was investigated for its antioxidant and spore germination inhibition activities. Dry mass of algae had 30.01 % moisture and 6.2 % of ash. Extractions were carried out using hot and sonicated methods. Sohxlet extract gave 21 % pet ether, 3.6 % protein, 25 % reducing sugar fractions. The sonicated extract had 13 % pet ether, 3.2 % protein and 31.3 % reducing sugar concentrations. The hot: sonicated extracts showed phenol (590 mg: 450 mg), Flavanoid (250:360), Antioxidant (54.8:50.7) and Reducing powers (0.050:0.045). The spore germination inhibition of both the extracts by cavity slide method, in comparison with standard fluconazole, exhibited an average of 95.5 % activity against Fusarium oxysporum and 90.5 % against Curvularia lunata.