Published Paper Details:

Prevalence of Bacterial Isolates Causing Community Acquired Urinary Tract Infections and its Antibiotic Resistance Pattern In Tertiary Care Hospital. Dr. Himani Brahmbhatt1, Resident doctor, Department of Microbiology Dr. Sejul K. Antala2, Assistant Professor, Department of Microbiology Dr. Pradnya Mahapure3, Resident doctor, Department of Microbiology Dr. Bansari Saradava4, Resident doctor, Department of Microbiology Dr. G.U. Kavathia5, Professor and Head of Microbiology Department of Microbiology, P.D.U. Medical College and Hospital, Rajkot. Abstract: Introduction: Urinary tract infection is the most common bacterial infectious disease after respiratory tract infection disease in community practice. Detection of UTI-causing pathogens and resistance of these pathogens to commonly prescribed antibiotics in clinical setups is essential and helpful in improving the efficacy of empirical treatment. Aims and Objectives: It aims to identify the most common UTI pathogens and their prevalence by sex and age group to improve treatment and management at this hospital. Material and Methods: 300 urine samples received at Tertiary Care Hospital, Rajkot during Jan-2024 to June-2024 were tested for bacterial pathogen by culture and Biochemical reaction. Results: Out of 300 urine samples, 46 (15%) were positive for urinary tract infection (UTI) isolates. Gender-wise, UTIs were more prevalent in female patients 25(54.34%) compared to male patients 21 (45.65%). The distribution of UTI cases across different age groups and genders revealed that the highest prevalence in females was in the 21-40 years age group (56%), while for males, it was in the >60 years age group (61.90%). E. coli was the most common isolate (67.39%). Antimicrobial susceptibility testing showed Aminoglycosides and carbapenems should be preferred over fluoroquinolones and cephalosporins. Conclusion: Present study reported that E. coli isolate was the most common pathogen causing UTI which mainly affected females. Aminoglycosides and meropenems showed higher sensitivity. This study will help to improve treatment recommendations in a specific geographical region. The study also allows comparison of the situation in Rajkot with other regions within and outside the state as well as in the country or outside the country. Key words: urinary tract infection; dysuria.