Published Paper Details:

The spleen is a critical organ involved in immune response, blood filtration, and the destruction of old red blood cells. Spleen disorders, including splenomegaly, can lead to significant health issues. Traditional and herbal medicines have been used for centuries to treat various ailments, including spleen disorders. This review aims to provide a comprehensive overview of medicinal plants with spleen-protective activity, highlighting their potential mechanisms of action, active constituents, and therapeutic efficacy. Through an extensive literature survey, plants such as Ipomoea digitata, Phyllanthus emblica, Andrographis paniculata, Curcuma longa and Tinospora cordifolia have been identified for their significant spleen-protective properties. The pharmacological basis of these plants includes antioxidant, anti-inflammatory, and immunomodulatory activities. Special emphasis is given to Ipomoea digitata, a plant with promising but not yet fully proven spleen-protective effects. Understanding the traditional uses and scientific evidence supporting these medicinal plants can pave the way for developing novel therapeutic agents for spleen-related disorders. This review explores the social impact and potential benefits of integrating these herbal remedies into modern healthcare systems. This review underscores the significant role of medicinal plants in spleen protection and encourages further research to validate their clinical efficacy and safety. The integration of these herbal remedies into contemporary medicine could offer a promising avenue for managing spleen-related disorders and enhancing public health.