Published Paper Details:

Pharmacokinetic properties are widely connected in the form of oral dose, to treat different kind of disease. This type of formulation is very quickly eliminated through the body so it became very challenging work to maintain the therapeutic effect. Some of medication work locally in gastric problem but it last very few times in the stomach. Now a days very different studies have been done to point out the formulation which can increase the drug lasting time in stomach. More increase stomach retention time of the dosage form, different kind of approaches are done, one such approach is the development of gastro retentive controlled drug delivery. It useful for many more drugs that are orally administered. GRDDS is a type of novel drug delivery system it increases the gastric residence time of the formulation, increase the bioavailability of the drug and used different kind of gastric related disease. GRDDS approaches, the factors affecting the gastric retention, advantages, and disadvantages are briefly discussed. Method for development of the Gastro-retentive Multi particulate System, Comparison of conventional and gastro retentive drug delivery systems, assessment of gastro retentive dose forms, use of polymeric material in gastro retentive formulations.