Published Paper Details:

. Cancer actually refers to a group of many related diseases that all have to do with cells. These cells tend to grow without control and exhibit an inadequate, inappropriate blood supply. Also, there is a core of cells subjected to microenvironmental stresses, which possess lower apoptotic potential through genetic alterations and therefore render them resistant to apoptosis. Cancer is among the leading causes of death in the world where the figures of cancer patients are increasing day by day. Cancer is a major public health problem whose estimated world new incidence rate is about 6 million cases annually or this makes it rank second after cardiovascular diseases as cause of deaths. Chemotherapy still remains as the main treatment mode for various cancers. Several synthetic anti-cancer drugs are available; however, its clinical use is limited by its side effects and drug interactions being a major drawback in their clinical use. Most currently used chemotherapy drugs against cancers are found to develop resistance, show non-selective toxicity towards normal cells and thus limit themselves through dose-related side effects. Therefore, cancer therapy and drug development for this disease remains one of the most serious tasks in clinical practice. On other hand plants could be a very good source bearing extremely valuable biologically active natural products which can have commercial usefulness.