Published Paper Details:

Research is focusing on the search for new types of natural chemotherapeutic agents derived from plants which are proving to be excellent sources of new compounds. This review aimed to highlight the information regarding physicochemical properties, Chemical Composition, Anticancer properties and their administrations of jackfruit. Artocarpus heterophyllus shows anticancer properties due to the presence of phytochemicals like lignans, saponins, flavonoids carotenoids, tannins, volatile acid steroids and also the properties such as anti-oxidant, anthelminthic, anti-inflammatory, anti-bacterial, anti-viral activities. The phytochemical constituent artocarpine have effect on cancer cells. Target specific agents that are capable of inducing selective apoptosis of cancer cells but are harmless to the normal cells are receiving considerable attention in the field of cancer prevention and therapy. The flavonoid compound artonine B have anti-cancerous effect on human cancer cells. Different studies are performed on this topic and reported. Also, further researches and studies are ongoing. OBJECTIVE: The objective of this article is to provide a detailed and systematic knowledge on the anti-cancer property of Artocarpus heterophyllus (jack fruit) and its medicinal values. METHODS: A vigorous, maximum sensitive and online search of the literature was performed in published articles in the last 20 years (JUNE 2000-JUNE 2020). The databases searched were MEDLINE (via PubMed) and Cochrane Library. CONCLUSION: Cancer is becoming a high profile disease in developed and developing worlds. In 2017 the WHO published that in 2015, 7.6 million people died from cancer related diseases with the majority of these people living in low-income countries. the demand for a cure and the prevention of cancer is extremely high. Experimental studies performed in the past suggest that, jackfruit possesses diverse medicinal uses including antioxidant, anti-inflammatory, antimicrobial, ant cariogenic, antineoplastic and hypoglycemic effects, inhibits melanin biosynthesis, possesses wound healing properties, and causes a transient decrease in the sexual performance. Target specific agents that are capable of inducing selective apoptosis of cancer cells, but are harmless to normal cells are receiving considerable attention in the fields of cancer prevention and therapy. Therefore, Artocarpus heterophyllus is a candidate for development as a Chemo preventive agent.