Published Paper Details:

ABSTRACT Background: The present research is based on formulation of celecoxib emulgel and determines in-vitro drug release and swelling index of prepared emulgel. Material and Methods: Pure drug of celecoxib was identified by using FTIR spectroscopy and preformulation study of emulgel was performed by using various methods like determination of lamba max, drug solubility studies, melting point of pure drug etc. The present formulation is based on carbapol 934 polymer and other key ingredient and excipients which was used in preparation of anti emulgel. Result: Evaluated the prepared emulgel by their physical appearance, PH, Rheology, Swelling index, microscopic studies, Drug content, % drug release. In all formulation batch, F3 batch formulation was give satisfactory result like that drug content 95.3%, cumulative drug release 92.9 %. Conclusion: As a result, the current study's results unambiguously showed that celecoxib emulgel presents a promising alternative to the traditional dose form. Nevertheless, additional clinical research is required to evaluate the effectiveness of this technique. After taking into account everything mentioned above, it was determined that the current research study's goal could be effectively met.