Published Paper Details:

In the current study, the anti-hypertensive medication felodipine or dispersible tablets that are employed via direct compression method are modelled and evaluated in vitro using a variety of super disintegrants. Guar gum, sodium starch glycolate, and Croscarmellose sodium were used as super disintegrants in the preparation of the dispersible felodipine tablet. Other excipients included mannitol, talc, magnesium stearate, microcrystalline cellulose, and others. Precompression characteristics of the prepared dispersible tablet, such as bulk and tapped density, angle of repose, cars index, etc., were assessed. The range contains all of the parameters. Studies on post-compression characteristics such as hardness, thickness, disintegration time, dissolution, and stability were also conducted. Out of all the formulations, the F1 formulation was determined to be the most optimised. The F1 formulation had a 15-second disintegration time and a 15-minute drug release percentage of around 100.047%. The stability investigations yield excellent results as well.