Published Paper Details:

The hemicyanin which has been found as very strong antibacterial activity. Hemicyanin acts as non-specific immune protein and acquies stronger antibacterial activity after glycosylation. The glycosylation of arthropod hemicyanin has been identified in Haliotis tuberculate.The diversity in glycan content and type of glycosylation of hemicyanin contribute to its functional properties and diversity These modification after the glycosylation of hemicyanin are also involved in pathogens recognition and bacterial invasion. The degree of glycosylation of hemicyanin subunits is largely affected by and depends on the presence of pathogens Glycosylation plays an important role in infectious diseases. Many important interactions between pathogens and hosts involve their carbohydrate structures (glycans). Glycan interactions can mediate adhesion, recognition, invasion, and immune evasion of pathogens. In recent years changes in many protein N/O-linked glycosylation have been identified as biomarkers for the development of infectious diseases and cancers. The principal findings and the roles of glycosylation of both pathogens and host cells in the context of human important infectious diseases. Understanding the role and mechanism of glycan-lectin interaction between pathogens and host cell which may create a new paradigm for discovering novel glycan-based hemicyanine therapies that can lead to functional cure of pathogens infection