Published Paper Details:

Ophthalmic problem is becoming very common globally over 2 billion people suffer from vision impairment. Eye drop are the most inexpensive ophthalmic formulation. Dry eye syndrome is one of the prevalent cause for irritant feeling in eyes. Dry eye syndrome is an interpalpebral ocular surface problem also called as Keratoconjuctivitis sicca, which cause damage to interpalpebral eye surface due to deficiency of tear or uncontrolled evaporation. Resulting in the damage to the ocular surface which is getting worsen day by day. There are several preparation of eye drop for dry eye condition. There are several studies which are currently being explored with much focus on adjusting the formulation of eye drop to enhance the retention time in the eye. Castor oil is used for its anti inflammatory and lubricant effects, it has been found that it helps in maintaining the lipid layer of tears called as tear film lipid thickness and helps in increasing tear film lipid layer stability. My review objective is the preparation of eye drop containing castor oil as the active ingredient, excipents and preservatives from preventing the microbial growth. the evaluation parameter such as ph, clarity, sterility, viscosity, surface tension were studied to identify the stability of the eye formulation.