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Background of study:-A study to assess knowledge regarding patient safety goals among nurses working at hospitals in selected areas in view to develop information booklet was conducted in partial fulfilment of requirement of award MSc.Nursingat Sinhgad college of nursing narhe,pune.Maharashtra affiliated to Sinhgad university Pune.Purpose:-study to assess knowledge regarding patient safety goals among nurses working at hospitals in selected areas in view to develop information booklet.Methodology:-100Sample size.Study approach:Quantative research approach.Non experimental descriptive study designDuration of study: 28 days. Non-probability convenient sampling technique will be used for the study. In this study, it refers to the facts, information acquired by staff nurse regarding patients safety goals prevention of coronary artery disease.Principle Result:- Percentage distribution of socio demographic characteristics of nurses(n = 100).Description of mean,SD of Knowledge Score about Patient safety goal among staff nurses was Mean was 15.6, SD was 3.53 and Maximum score From Respondent was 22.Frequency and percentage wise distribution of knowledge score of staff nurses of selected hospitals that highest percentage of Good Knowledge score 67(67%), 10(10%) of them had Excellent knowledge.Association Between the knowledge score and demographic variables of Staff Nurses.Chi square values were calculated to find out the association between the knowledge score and demographic variables of Staff Nurses.A significant association was found between the knowledge score and Area of Experience.