Published Paper Details:

To get rid of certain drawbacks of traditional formulations, considerable attention has been paid to lipid-based drug delivery systems in recent years. Solid lipid nanoparticles (SLNs) and nano-structured lipid carriers (NLCs) are promising delivery systems among these because of their ease of manufacturing processes, ability to scale up, biocompatibility, and biodegradability of formulation constituents, as well as a number of additional benefits that may be related to a particular route of administration or the nature of the materials that are to be loaded onto these delivery systems. The use of many Nano-structured technologies for ocular medication delivery has shown some encouraging outcomes. During the 1990s, solid lipid nanoparticles (SLNs) have been investigated as possible drug delivery systems. Due to the fact that SLNs are made from physiological lipids, they do not exhibit bio toxicity. Since they may increase drug absorption via the cornea and increase the bioavailability of both hydrophilic and lipophilic medicines in the eye, SLNs are particularly helpful in the delivery of drugs to the eye. Another advantages of SLNs is that they allow autoclave sterilization, which is required before creating ocular preparations. This review outlines anatomy and physiology of eye, challenges in ocular drug deliver, brief overview about SLN with their application in common ocular diseases, future perspective of ocular drug delivery.