Published Paper Details:

Abstract: In this review article we discussed the types, preparation and evaluation of liposomal formulation of tamoxifen for the breast cancer. The breast cancer remains the most common cancer among women world wide prevailing disease world wide that requires, effective and rational therapy for this purpose the use of varies treatments modalities should be optimized. According to the risk benefits ratio of the therapeutic agents employed in the patients. Tamoxifen is an oral estrogen antagonist drug. Which is an adjust treatment of breast cancer when used in low doses. Liposomes are spherical vesicles consisting one or more phospholipid bilayer which are under extensive investigation as drug carrier for impairing the delivery of bioactive agent and many different compounds in biological. The Tamoxifen encapsulated in liposome by different methods like modified either Injection method (MEIM) & thin film Hydration method (TFHM) etc. The drug encapsulation in liposomes has provided an opportunity to improve therapeutic drug mainly through changes in biodistribution and targeting of drug to certain tissue. The role of liposomes as a drug delivery system is to provide drug in controlled manner.