Published Paper Details:

The diagnosis of autoimmune diseases faces various obstacles at present. The diverse nature of autoimmune disorders and the overlap of symptoms create difficulties in identifying a specific condition. Furthermore, the absence of distinct biomarkers that are unique to each disease adds complexity to the diagnostic procedure, resulting in delays and potential misclassification. While considering the diagnosis challenge, Polymerase chain reaction (PCR)-based methods have emerged as powerful tools in the diagnosis and monitoring of autoimmune diseases. This review aims to outline the recent advancements in PCR-based techniques and their applications in autoimmune disease diagnosis and monitoring. By leveraging PCR, researchers and clinicians have made substantial progress in improving the understanding, early detection, and differentiation of autoimmune disorders, thereby enhancing patient care and outcomes. PCR-based approaches have revolutionized the diagnosis and monitoring of autoimmune diseases, providing valuable insights into disease pathogenesis, patient stratification, and treatment efficacy. Continued advancements in PCR technologies hold great promise for improving the accuracy, efficiency, and accessibility of autoimmune disease diagnostics, ultimately leading to personalized and targeted therapeutic interventions.