Published Paper Details:

Oral hygiene is essential to a person's overall health. To develop an oral care cosmeceutical as tooth whitening formulation, propane extract of whole peel (WBP) and inner peel of banana (BPI) Musa paradisiaca L. were prepared and evaluated for their phytoconstituents. The extracts (WBP) and (BPI) were then used to prepare teeth whitening formulations T2 and T3. The formulations were evaluated with respect to their physico-chemical parameters, stability studies and in-vitro cosmeceutical use as tooth whitening agents in comparison with the commercial standard formulation T4. Statistical results are expressed as : Mean + S.E.M (n 10), the values "P<0.05 is significant as compared to placebo, **P<0.01 is very significant as compared to placebo, ***P<0.001 is highly significant as compared to placebo.The demand for herbal based product such as toothpaste is high these days. Consumers believed by using herbal based toothpaste are safe, effective and less toxicity because less and only safe chemical used as compared to the synthetically produced toothpaste. Therefore, this study was aimed to formulate and evaluate new polyherbal toothpaste which containing herbal extracts that available in Malaysia to treat periodontal problem. The polyherbal toothpaste was formulated using three herbal extracts namely banana peel (Musa acuminate), guava leaves (Psidium guajava) and orange peel (Citrus arranticum) and tested against Staphylococcus aureus. Bacillus cereus. Escherichia coli and Pseudomonas aeruginosa with different concentrations varying from 100 mg/mL. 250 mg/mL and 500 mg/mL. The significant inhibition has seen against Staphylococcus aureus (12-18 mm) followed by Bacillus cereus (11-15 mm) and there is no inhibition for both Escherichia coli and Pseudomonas aeruginosa. The formulated toothpaste was also evaluated with the standard physiochemical parameters along with the antimicrobial activity. The formulated toothpaste showed potent inhibition against gram positive bacteria but not against gram negative bacteria. Thereby. it opens a window for future study to enhance the ability of the toothpaste and to prove the efficacy and safety of the formulated toothpaste.