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Ayurveda is a prominent traditional medical practice that started in India. It uses a combination of treatments and lifestyle adjustments to cure sickness and maintain health. Adjuvant heavy metals, known as bhasmas (nanoparticle of metal & mineral) in Ayurvedic medicine, are widely included into basic herbo-mineral (combination of herbal and metals) formulations for their attributed medicinal effects and to boost potency. Heavy metals found in Ayurvedic medicines include lead, arsenic, and mercury. The toxicity of heavy metals generated by Ayurvedic medicines is widely recognized in the literature. The metal is "purified" during the traditional production of bhasmas (nanoparticle of metal & mineral) by several cooling and heating cycles, as well as the use of particular "mineral herbs." However, owing to inadequate quality control, which allows for contamination, adulteration, or faulty purification, the quantity of heavy metals in current formulations may be excessive. However, the concentration of heavy metals in modern formulations may be excessive due to poor quality control, which allows for contamination, adulteration, or improper purification. Several metallic preparations known as Bhasma have been used in clinical practice since the 8th century AD, according to Ayurvedic descriptions. Ayurvedic Puta system (Heating system) states that metals or minerals should be heated to high temperatures for melting and then quenched in suitable media such as herbal juices or decoctions for specified times. These methods are repeated several times to obtain the Bhasma (incinerated metals). The toxic effects of the metals are not only neutralized, but also transformed into biologically active nanoparticles during this process.