Published Paper Details:

Urinary tract infection (UTI) is one of the most common health problems among pregnant women and the reason for morbidity during pregnancy in worldwide. Occurrence of Gram-negative bacteria is more frequent and next to E.coli, Klebsiella spp. is a recurrently isolated organism causing UTI. Klebsiella pneumonia, Gram-negative, encapsulated, and nonmobile bacteria are bacteria that normally live in intestines and feces. They also have a high tendency to become antibiotic resistant. A total 183 samples having UTI obtained out of 300 samples from pregnant women, investigated for identification and characterization of the uropathogenic isolates. Klebsiella pneumoniae was obtained as the 2nd most bacterial pathogen having 12.5 % of occurrence. The identified pathogens were then screened for pathogenic factors namely haemolysin production, Mannose Resistant and Mannose sensitive Haemagglutination (MRHA, MSHA), Cell surface hydrophobicity and Serum resistance, biofilm formation, production of siderophores by recommended methods. Piperacillin/Tazobactam(P/T) and Norfloxacin (Nx) were found to be the most effective drug against Klebsiella spp. and biofilm production (65.2%) was observed as the most frequent pathogenic factor in Klebsiella spp.