Published Paper Details:

Since ancient times, herbal remedies have been the most important type of medicine in all societies. Various plant extracts have been found to exhibit a wide range of biological activity, including immunomodulator activity, hepatoprotective activity, antilipidemic action, and so on. Plant extracts have high in vitro bioactivity but low in vivo in animal models. The primary reasons for the poor bioactivity of herbal extracts are that the bioactive components of these herbs have multiring molecular structures that cannot be permeated into the blood by simple passive diffusion, and the bioactive phytoconstituents are mostly water soluble, resulting in their lack of lipid dissolubility.To address this issue, pharmaceutical researchers devised a unique lipid-based drug delivery system that is favourable in delivering the herbal medication at the site of action, reducing adverse effects while increasing absorption and bioavailability. The integration of standardised herbal extracts into phospholipids to generate a lipidfriendly complex called a herbosome is one delivery technique proposed to increase the in vivo solubility and thus bioavailability of ineffectively dissolvable herbal medications. The current study's goal is to accumulate all herbosome-related data that will be useful to academics.