Published Paper Details:

The term "oxidative stress" refers to an imbalance in the body's antioxidant enzymes between free radicals and their stabilizing agents. Normal cellular metabolism can generate reactive oxygen species, also known as free radicals, which interact with biomolecules including protein, lipid, and DNA to harm cells and bring about deteriorative changes. Free radicals are essential for cellular communication and physiological control at low concentrations, but at excessive concentrations, they can harm cells. In contrast, antioxidants reduce oxidants by giving their own electron to stabilize free radicals and turn them into non-reactive compounds in order to reduce the negative effects that these radicals have on the cell. Chronic disorders including cancer, diabetes, neurodegenerative diseases, and cardiovascular diseases all have oxidative stress as a major contributor to their etiology. Increasing amounts of pro-oxidant substances over time might result in structural flaws at gene expression anomalies brought on by functional changes at the mitochondrial DNA level, as well as in a number of enzymes and cellular structures. The current way of life, which includes eating processed food, being exposed to a variety of chemicals, and not exercising, is a significant factor in the development of oxidative stress. However, the capacity of medicinal plants with antioxidant capabilities to cure or prevent a number of human illnesses in which oxidative stress appears to be a contributing factor has been utilized. The diseases that oxidative stress is one of the triggers for are discussed in this overview, along with the antioxidant chemicals obtained from plants and their processes of antioxidant defenses that can aid in the prevention of these diseases. The impacts of antioxidant compounds employed to lower oxidative stress in a number of pathological dysfunctions in both positive and negative conditions are finally reviewed.