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Paper Title
ZERO AND FIRST ORDER DERIVATIVE METHOD DEVELOPMENT AND VALIDATION OF SILODOSINE BULK AND ITS PHARMACEUTICAL FORMULATION BY USING UV-VISIBLE SPECTROSCOPY
Authors
Mr. Santosh A. Waghmare, Ms. Snehal Giri, Mr. Amiksh K. Pukale, Ms. Pratibha Kale, Ms.Snehal Jadhav
Keywords
UV, Silodosine, Zero order, First order
Abstract
A simple, sensitive, rapid and reproducible UV method has been developed and validated for Calibration determination of Silodosine in bulk and in pharmaceutical formulation. For development of UV method for Standard stock solutions of Silodosine are prepared by using methanol and further dilutions for sample are prepared by using distilled water. Quantitative method development by zero order derivative method and first order derivative method was measured at 266 and 325nm respectively. Standard curve showed a regression coefficient zero order derivative and first order derivative is 0.999 and 0.998 respectively. The method was validated as per ICH guidelines. The precision and repeatability results showed % RSD less than 2%.
IJCRT's Publication Details
Unique Identification Number - IJCRT1803133
Paper ID - 184356
Page Number(s) - 247-251
Pubished in - Volume 6 | Issue 1 | March 2018
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Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Mr. Santosh A. Waghmare, Ms. Snehal Giri, Mr. Amiksh K. Pukale, Ms. Pratibha Kale, Ms.Snehal Jadhav, "ZERO AND FIRST ORDER DERIVATIVE METHOD DEVELOPMENT AND VALIDATION OF SILODOSINE BULK AND ITS PHARMACEUTICAL FORMULATION BY USING UV-VISIBLE SPECTROSCOPY", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.6, Issue 1, pp.247-251, March 2018, Available at :http://www.ijcrt.org/papers/IJCRT1803133.pdf
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Volume 13 | Issue 10
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Submit Manuscript Online Impact Factor: 7.97 Review Results : Within 02-03 Days Paper Publication : Within 02-03 Days
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
ISSN and 7.97 Impact Factor Details
ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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