Published Paper Details:

The present paper deals with the microwave assisted synthesis and screening of antimicrobial activity of Schiff base derivative of 2- Amino benzimidazole and their cobalt complex. The synthesized ligand, and their cobalt complex were screened for their antimicrobial and antifungal activity. Schiff base metal complexes are an area of increasing interest. These complexes have numerous applications, such as, in the treatment of cancer, as antibactericide agents, as antivirus agents, as fungicide agents and for other biological properties. Benzimidazoles are very useful intermediates/subunits for the development of molecules of pharmaceutical or biological interest. In the present study Schiff base of Co(II) complexes synthesized from the Schiff base Ligand. And the Schiff base ligand 1-(anthracen-9-yl)-N-(1H-benzimidazol-2-yl )methanimine synthesized by the reaction between 2-amino benzimidazole with 9-anthracenecarboxaldehyde under microwave irradiation .The synthesized compounds were purified by recrystallisation and Further, compounds screened for antimicrobial activity against Escherichia coli (NCIM 2256), Staphylococcus aureus (NCIM 2079) , Pseudomonas aeruginosa (NCIM 2257), Klebsiella pneumoniae (NCIM 5432), Candida albicans (ATCC 10231)and Streptococcus pneumoniae (ATCC 49619).