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NEPHROTIC SYNDROME: AN INTEGRATIVE REVIEW OF EPIDEMIOLOGY, ENVIRONMENTAL TRIGGERS AND CLINICAL IMPLICATIONS
Authors
Lipsa Dehal,Gurinder Kaur Walia,Navjot Kaur
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Keywords
Nephrotic syndrome, epidemiology, lifestyle, environmental risk, prevention, kidney disease.
Abstract
Peripheral edema, severe proteinuria, and hypoalbuminemia often in combination with hyperlipidemia are the hallmarks of nephrotic syndrome (NS). People typically exhibit fatigue and edema, but no indications of severe liver disease or heart failure. NS can be identified by its distinctive medical symptoms, hypoalbuminemia, and severe proteinuria. Understanding NS outside of the clinic necessitates paying consideration to its epidemiological trends, lifestyle causes, and preventive methods, even though its clinical manifestations and management are well-established. With a growing burden seen in both developed and low-resource nations, this study summarizes global and regional epidemiological patterns, emphasizing differences in prevalence among age groups, gender, and geographic contexts. The importance of lifestyle and environmental factors, such as eating patterns, obesity, sedentary behavior, and exposure to environmental pollutants such pesticides, heavy metals, and air pollution, is highlighted by new research. Disease risk and consequences are further increased by socioeconomic variables, especially poverty, delayed access to healthcare, and urban-rural inequities. Understanding disease heterogeneity also heavily relies on immunological triggers and genetic predispositions. Crucially, there are ways to lower the incidence and course of disease through preventive measures that range from public health initiatives that support a healthy diet and regular exercise to early screening of groups at risk and reducing environmental exposures. This review highlights a comprehensive approach to NS by combining epidemiological findings with lifestyle and prophylactic aspects, thereby bridging the gap between clinical therapy and community-level health promotion.
IJCRT's Publication Details
Unique Identification Number - IJCRT2509271
Paper ID - 293703
Author type - Indian Author
Page Number(s) - c305-c317
Pubished in - Volume 13 | Issue 9 | September 2025
DOI (Digital Object Identifier) -
No Of Downloads - 39
Author Country - India, 147002, Patiala, Patiala, 147002, Humanities All
Publisher Name - IJPUBLICATION | www.ijcrt.org | ISSN : 2320-2882
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Lipsa Dehal,Gurinder Kaur Walia,Navjot Kaur, "NEPHROTIC SYNDROME: AN INTEGRATIVE REVIEW OF EPIDEMIOLOGY, ENVIRONMENTAL TRIGGERS AND CLINICAL IMPLICATIONS", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.13, Issue 9, pp.c305-c317, September 2025, Available at :http://www.ijcrt.org/papers/IJCRT2509271.pdf
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