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Background: The SARS COV-2 pandemic has led to a disruption of synchronous education in the classrooms throughout the world. In this situation, E-learning has been a boon for sustenance of continued uninterrupted teaching and learning processes without geographical restrictions. However, E-learning is a novel experience for majority of students. Aim: The study was therefore, conducted with the aim to investigate the attitude of nursing students in Farasan, Jazan University, KSA towards e-learning to evaluate if e-learning enables students to continue their education similar to the traditional approach during this global health crisis (SARS COV-2). Methodology: A cross-sectional survey was carried out using online Google survey questionnaire with 5-point's likert's scale. The study had 228 nursing students (aged between 19-23 years) from Department of Nursing, Farasan University College. The students were from different academic years during the academic semester 2020-2021. The survey questionnaire focused on student's attitude towards synchronized E-learning and had multiple questions that made up a score that reflects their attitude towards synchronized online learning experience during current situation of SARS Cov-2 precautions. The study was focused on research investigating if e-learning enables students to continue their education similar to the traditional approach. The survey was voluntarily, and all data were collected and recorded via Google forms with maintaining high levels of anonymity. Since the study does not require any kind of sampling from human body directly and indirectly, informed consent was considered as the ethical approval form. Descriptive statistics was performed for data analyses. Spearman correlation was applied to find statistical difference between different variables of the study. Statistical significance was fixed at P-value <0.05. Results: The results revealed that The college administration maintained all strings attached between faculty, students, and the administrative assistants and closely monitored all educational activities Despite its several benefits, students are of opinion of hybrid teaching sessions as they feel that E-learning alone cannot compensate with the psychomotor skills they develop during actual laboratory sessions and also the cognitive skills which they develop during actual seminar presentation in front of audience and Instructors/Faculties. Overall, 68.6% of students had negative attitudes towards exclusive online laboratory sessions and seminar presentation. Highest level of unsatisfaction was recorded for the final year students (56.6%) and the lowest level of total negative attitude was noted among academic students in the first and second year students (12%) using e-learning. However, network issues remained as one of the most common reasons of the negative attitude among students at all levels who belong to remote areas (31.1%). Conclusions and Recommendations: Students' feedback can help institutions to improve the exclusive e-learning experience for students in the time of the pandemic. Since synchronized e-learning at this large scale is a new experience for student's community, the outcomes of the study could be helpful to plan a systematic strategy for further improvement of e-learning. A moderately negative correlation was found between e-learning and the attitudes (r=-0.564). Students' feedback as the outcomes of present study could help to chalk out plans for future.