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TUMOURS OF MINOR SALIVARY GLANDS IN RARE SITES: A CASE SERIES
Authors
Dr. Apurv Shroff,Dr. Jaspreet Kaur,Dr. Navaudhyam R,Dr. Anu Agrawal
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Keywords
Acinic Cell Carcinoma, Parapharyngeal mass, Adenoid Cystic Carcinoma, Minor Salivary Gland
Abstract
This study has been undertaken to investigate the minor salivary gland neoplasms arising from uncommon anatomical regions such as the parapharyngeal space and buccal mucosa are exceedingly rare. Their clinical detection is often delayed due to non-specific symptoms and concealed locations, frequently resulting in late-stage diagnosis.[1][2] Acinic cell carcinoma (ACC), more commonly arising in the parotid gland, and adenoid cystic carcinoma (AdCC), recognized for its perineural invasion and protracted course, are infrequent in these sites.[3][4][5] Awareness of their varied presentations is essential to guide timely diagnosis and appropriate management.
Case Summary: The first case features a 50-year-old woman with progressive dysphagia, later diagnosed with ACC in the left parapharyngeal space. MRI revealed a well-defined enhancing mass, and histopathology confirmed the diagnosis with immunoreactivity for SOX10, DOG1, and PanCK.[6] Surgical resection was curative. The second case involved a 46-year-old woman with a gradually enlarging cheek mass, identified as Grade II AdCC of the buccal mucosa with perineural invasion and involved margins.[5] She was advised adjuvant chemoradiation following surgical excision.
Conclusion: These cases highlight the diagnostic challenges associated with minor salivary gland tumors in atypical regions.[1][2] Multimodal imaging and histopathological evaluation remain pivotal, while complete surgical excision is central to management.[3] Adjuvant therapy may be necessary depending on histological features and margin status.[5] Sustained follow-up is imperative due to the risk of delayed recurrence.[5]
IJCRT's Publication Details
Unique Identification Number - IJCRT2507665
Paper ID - 291604
Author type - Indian Author
Page Number(s) - f775-f779
Pubished in - Volume 13 | Issue 7 | July 2025
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No Of Downloads - 67
Author Country - India, 110029, New Delhi, New Delhi, 110029, Humanities All
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Dr. Apurv Shroff,Dr. Jaspreet Kaur,Dr. Navaudhyam R,Dr. Anu Agrawal, "TUMOURS OF MINOR SALIVARY GLANDS IN RARE SITES: A CASE SERIES", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.13, Issue 7, pp.f775-f779, July 2025, Available at :http://www.ijcrt.org/papers/IJCRT2507665.pdf
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