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Published Paper Details:
Formulation And Evaluation Of Avaleha From Anacyclus Pyrethrum Linn. For Tongue Paralysis And Tooth Ache
Authors
Sakshi Badrinarayan Ghanmode,Kasturi Ravindra Khule
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Keywords
Avaleha, Anacyclus pyrethrum, paediatric formulation, tongue paralysis, toothache
Abstract
This study focuses on the formulation and evaluation of a paediatric dosage form Avaleha (semisolid herbal preparation) using Anacyclus pyrethrum Linn., commonly known as Akkarkara, aimed at managing tongue paralysis and toothache in children. Rooted in classical Ayurvedic knowledge and supported by modern pharmacological insights, this project addresses the critical need for a safe, effective, and palatable herbal alternative for paediatric patients, particularly for conditions affecting speech and oral health.
Akkarkara is known for its nervine, analgesic, anti-inflammatory, and antimicrobial properties. It has been traditionally used in conditions like facial paralysis, speech disorders, and dental ailments. In this study, a herbal Avaleha was developed using a combination of Akkarkara flower bud powder along with Amla, dates, jaggery, ghee, sesame oil, and a blend of aromatic and therapeutic spices. The formulation was modified into a lollipop form for improved acceptability and administration in children, ensuring prolonged mucosal contact and enhanced effectiveness.
The formulation was evaluated for organoleptic properties (colour, taste, odour, texture), pH, moisture content (LOD), ash value, and microbial load. The Avaleha exhibited a pH of 5.3-5.7, suitable for oral administration, with acceptable levels of moisture (3.68%) and ash content (9.5%). Phytochemical analysis revealed the presence of alkaloids, terpenoids, flavonoids, saponins, tannins, and glycosides. Microbial tests demonstrated antibacterial activity, with a zone of inhibition against E. coli measuring 16-18 mm and a 66.2% reduction in colony-forming units.
The study concludes that the developed Avaleha offers a child-friendly, natural, and therapeutically potent alternative for treating paediatric tongue paralysis and toothache. This innovative herbal formulation not only aligns with Ayurvedic principles but also meets modern safety and efficacy standards, warranting further pharmacological and clinical exploration.
IJCRT's Publication Details
Unique Identification Number - IJCRT2507511
Paper ID - 291413
Author type - Indian Author
Page Number(s) - e432-e447
Pubished in - Volume 13 | Issue 7 | July 2025
DOI (Digital Object Identifier) -
No Of Downloads - 79
Author Country - India, 400612, Dombivli, Dombivli, 400612, Pharmacy All
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Sakshi Badrinarayan Ghanmode,Kasturi Ravindra Khule, "Formulation And Evaluation Of Avaleha From Anacyclus Pyrethrum Linn. For Tongue Paralysis And Tooth Ache", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.13, Issue 7, pp.e432-e447, July 2025, Available at :http://www.ijcrt.org/papers/IJCRT2507511.pdf
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