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Published Paper Details:
Formulation And Evaluation Of Fast Disintegrating Tablets Without Disintegrating Agent
Authors
Gosavi Sarthak Abhay,Deshmukh D.B.,Jorvekar kiran Govind
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Keywords
Rapid disintegrating tablets, patient compliance, sublimation, spray drying, freeze drying.
Abstract
The novel formulation of Fast Disintegrating Tablet (FDT) without using a disintegrating agent was prepared and evaluated. The purpose of this investigation was to develop a fast-disintegrating tablet by using (API) as a model drug. The formulation prepared by sublimation technique by using camphor as a sublimating agent. Disintegration is obtained by the porous structure of the tablet which is obtained by sublimation of camphor. This research mainly includes the drug delivery system which is cost effective and easy for manufacturing. Porosity plays a major role in this system. As porosity will increase the disintegration time will decrease means tablets will disintegrate fast and drug release will also be good. The most widely used and appropriate route of administration for FDT is the oral route because of versatility, simplicity of intake, and most importantly patient compliance. FDT are modern system of drug delivery because it has leas disintegration time in comparison with normal tablets and gives disintegration of within a few seconds to minutes. The study curried out on five different combination (i.e. F1 to F5), and the F4 formulation shows better test results which disintegrates in 30 sec which is within the limit. The prepared FDT were characterized for hardness, weight variation, friability, disintegration time, content uniformity.
IJCRT's Publication Details
Unique Identification Number - IJCRT2505863
Paper ID - 286507
Author type - Indian Author
Page Number(s) - h475-h482
Pubished in - Volume 13 | Issue 5 | May 2025
DOI (Digital Object Identifier) -
No Of Downloads - 138
Author Country - India, 413714, Sangamner, Sangamner, 413714, Pharmacy All
Publisher Name - IJPUBLICATION | www.ijcrt.org | ISSN : 2320-2882
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Gosavi Sarthak Abhay,Deshmukh D.B.,Jorvekar kiran Govind, "Formulation And Evaluation Of Fast Disintegrating Tablets Without Disintegrating Agent", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.13, Issue 5, pp.h475-h482, May 2025, Available at :http://www.ijcrt.org/papers/IJCRT2505863.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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