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A Protocol Of Assessing Medodushti With Special Reference To Nonalcoholic Fatty Liver Disease
Authors
Dr. Vijayalaxmi Sujay Patil,Dr. Medha Mahesh Joshi,Dr. Dhananjay S. Khot,Dr. Pratiksh D. Talwar
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Keywords
Keywords: Medodushti, Nonalcoholic Fatty Liver disease, Medodhatu, Medovruddhi, Medodhatwagnimandya
Abstract
Abstract: Nonalcoholic fatty liver disease (NAFLD) is emerging as an important cause of liver disease in India. Epidemiological studies suggest prevalence of NAFLD in around 9-32% of general population in India with higher prevalence in those with overweight or obesity and those with diabetes or prediabetes which can be correlated with Medodushti. Over the past couple of decades , it has become increasingly clear that Nonalcoholic Fatty Liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are the significant causes of liver disease.In Ayurveda, NAFLD may be understood as Medodushti. A vast spectrum of diseases comes under comes under Medodushti ranging from Obesity, Hyperlipidaemia, Diabetes Mellitus. According to Charakacharya, Avyama (no exercise), Divaswapna (sleep at day / excessive sleep), Snigdha, Guru , Shita Medya (food which increases lipids), Atimadya sevan (excessive alcohol consumption) leads to Dhatwagnimandya specially Medodhatwagnimandya which may lead to Medodushti. Vitiation of Medovaha strotas takes place in Medodushti or Medorog. The formation of Medodhatu from Mansa dhatu when acted upon by Meda Dhatwagni on Medopachak Amansha. If any disturbance found in these above pathways during formation of Medodhatu, it may lead to Medodushti i.e. either Vruddhi or Kshya (increase or decrease) of the Medodhatu. NAFLD is a metabolic disorder of hepatic origin. Thus, the treatment of NAFLD should be directed toward normalization of liver functions as well as to the reduction of Insulin resistance. Study Design is randomized controlled clinical study, Study Type is Interventional study Sample size is 134 Subjects (67 in each group) Sample selection techniques: Selections of subjects will be done by computer generated randomization list. Subjects in the age group of 30-65 years of irrespective sex having cardinal features of Medodushti pain in the Right upper quadrant/ epigastric region of the abdomen, feeling of nausea and vomiting, loss of appetite, burning sensation in the abdomen and clinical sign and symptoms suggesting NAFLD . o Criteria for Selection of Subjects: Subjects with signs and symptoms suggesting NAFLD will be selected from OPD Deptartment of Kayachikitsa (MAM's Sumatibhai Shah Ayurved Mahavidyalaya, Pune & PDEA's College of Ayurved & Research centre, Nigdi Pune). Approval of the study will be taken after presentation from institute's ethics committee. The cases will be enrolled after describing the treatment and obtaining informed consent in English and local language. Subjects eligible for inclusion criterion who will be selected for clinical trial, drugs are Standardized and well authenticated & will be procured from market. Interventional trial will be measured and by proper statistical analysis the observations of parameters are assessed.
IJCRT's Publication Details
Unique Identification Number - IJCRT2502095
Paper ID - 276180
Author type - Indian Author
Page Number(s) - a803-a814
Pubished in - Volume 13 | Issue 2 | February 2025
DOI (Digital Object Identifier) -
No Of Downloads - 136
Author Country - India, 411028, Pune, Pune, 411028, Humanities All
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Dr. Vijayalaxmi Sujay Patil,Dr. Medha Mahesh Joshi,Dr. Dhananjay S. Khot,Dr. Pratiksh D. Talwar, "A Protocol Of Assessing Medodushti With Special Reference To Nonalcoholic Fatty Liver Disease", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.13, Issue 2, pp.a803-a814, February 2025, Available at :http://www.ijcrt.org/papers/IJCRT2502095.pdf
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