Published Paper Details:

Diabetes mellitus is a chronic metabolic disorder caused by carbohydrate, fat, and protein metabolism problems. Genetic predispositions and environmental influences contribute to the disease, presenting significant challenges to patients' health. There are two types of diabetes, Type I and Type II. Both lead to elevated blood glucose levels (hyperglycemia). Several complications are associated with persistent hyperglycemia, including microvascular problems affecting the eye, kidneys, and nerves, as well as macrovascular problems like accelerated artery hardening, which increases heart disease, stroke, and peripheral artery disease risks. It is essential to focus on the prevention and management of diabetes-related complications in order to mitigate their impact on micro and macrovascular health. It is important to consider alternative treatment options as these medications can pose undesirable side effects. Medication, dietary adjustments, and regular exercise are all part of comprehensive diabetes management. Our study was aimed of the present study is to explore the anti-oxidant and anti-diabetic activity in the leaves of Stachytarpheta urticifolia. A comprehensive study was conducted to examine Stachytarphata urticifolia, a traditional botanical remedy, for its phytochemical composition, antioxidant potential, and effectiveness against diabetes. In this study, Stachytarphata urticifolia was found to exhibit significant diabetic-fighting and anti-oxidant properties. In addition to phenolic compounds, flavonoids, alkaloids, and terpenoids, Stachytarphata urticifolia contains hundreds of bioactive compounds. Phytochemicals such as these, which possess anti-oxidant and anti-diabetic properties, are considered to be promising therapeutic choices for humans who are suffering from diabetes or metabolic disorders. Stachytarphata urticifolia has shown remarkable antioxidant activity over the past few decades, which has been demonstrated to be helpful in preventing oxidative damage and preventing the onset of chronic diseases like diabetes by battling free radicals and combating oxidative stress. The in vitro studies of S. urticifolia were conducted in order to evaluate its anti-diabetic potential. There have been studies conducted in vitro that examined key enzymes associated with carbohydrate metabolism in an attempt to determine whether Stachytarphata urticifolia inhibits carbohydrate digestion and absorption by inducing moderate inhibitory effects on amylase, glucose oxidase, and glucose uptake. There was no doubt that S. urticifolia is capable of reducing complications associated with diabetes and these findings suggest that it may be useful for patients with diabetes who need to mitigate these complications. As part of this study, we examined S. urticifolia, a well-known traditional plant, for its phytochemical composition and potential anti-oxidant and anti-diabetic effects. The anti-oxidant potential of S. urticifolia and its moderate anti-diabetic activity were also found in our study. Based on the results of this study, S. urticifolia might be of benefit to diabetic patients as a therapeutic agent.