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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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Ms.Chavan Dipali Vilas,Ms.Kadu Shubhangi Sitaram,Ms.Gadve Vishakha Ashok,Ms.Kamble Pranita Pramod
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Keywords
Asthma , Chronic etc.
Abstract
Asthma is the most common inflammatory disease of the lungs. The prevalence of asthma is increasing in many parts of the world that have adopted aspects of t Western lifestyle, and the disease poses a substantial global health and economic burden. Asthma involves both the large-conducting and the small- conducting air ways, and is characterized by a combination of inflammation and structural remodeling that might begin in utero. Disease progression occurs in the context of a developmental background in which the postnatal acquisition of asthma is strongly linked with allergic sensitization. Most asthma cases follow a variable course, involving viral- induced wheezing and allergen sensitization, that is associated with various underlying mechanisms (or endotypes) that can differ between individuals. Each set of endotypes, in turn, produces specific asthma characteristics that evolve across the life course of the patient. Strong genetic and environmental drivers of asthma interconnect through novel epigenetic mechanisms that operate prenatally and throughout childhood. Asthma can spontaneously remit or begin de novo in adulthood, and the factors that lead to the emergence and regression of asthma, irrespective of age, are poorly understood. None the less, there is mounting evidence that supports a primary role for structural changes in the airways with asthma acquisition, on which altered innate immune mechanisms and microbiota interactions are superimposed. On the basis of the identification of new causative pathways, the sub phenotyping of asthma across the life course of patients is paving the way for more-personalized and precise pathway- specific approaches for the prevention and treatment of asthma, creating the real possibility of total prevention and cure for this chronic inflammatory disease.
IJCRT's Publication Details
Unique Identification Number - IJCRT24A4863
Paper ID - 258694
Author type - Indian Author
Page Number(s) - q235-q242
Pubished in - Volume 12 | Issue 4 | April 2024
DOI (Digital Object Identifier) -
No Of Downloads - 81
Author Country - India, 413502, Lohara ,Dist -Osmanabad, Lohara ,Dist -Osmanabad, 413502, Pharmacy All
Publisher Name - IJPUBLICATION | www.ijcrt.org | ISSN : 2320-2882
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Ms.Chavan Dipali Vilas,Ms.Kadu Shubhangi Sitaram,Ms.Gadve Vishakha Ashok,Ms.Kamble Pranita Pramod, "ACOMPREHENSIVE OUTLOOK, ASTHMA"", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.12, Issue 4, pp.q235-q242, April 2024, Available at :http://www.ijcrt.org/papers/IJCRT24A4863.pdf
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The International Journal of Creative Research Thoughts (IJCRT) aims to explore advances in research pertaining to applied, theoretical and experimental Technological studies.
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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