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ugc approved journal, UGC CARE Journal, ugc approved list of journal, ugc care journal, UGC CARE list, UGC-CARE, care journal, UGC-CARE list, Journal publication, ISSN approved, Research journal, research paper, research paper publication

  Authors

Mr. Saqlain Khan Gaffar Khan,Ms. Shabnam Rahim Sheikh,Ms. Swati Prakash Jamathe,Ms. Payal Santosh Rathod,Ms. Vishwaja Anil Mahalle

  Keywords

Golden Therapy, Turmeric, Emulgel formulation, Anti-inflammatory, Antioxidant, Dermatological applications, Excipients, Physicochemical characterization, In vitro studies, In vivo evaluations, Skin permeation, Rheological properties, Skin compatibility, Drug release kinetics, Animal models.

  Abstract


Golden Therapy: Crafting and Assessing Turmeric Emulgel Formulation is a comprehensive study aimed at formulating and evaluating the efficacy of a turmeric-based emulgel for potential therapeutic applications. Turmeric, renowned for its medicinal properties, particularly its anti-inflammatory and antioxidant effects attributed to curcumin, serves as the key ingredient in this formulation. The emulgel combines the benefits of both emulsion and gel systems, providing enhanced skin permeability and prolonged drug release. The research begins with the development of the emulgel formulation using a combination of hydrophilic and lipophilic ingredients to optimize stability, texture, and drug release characteristics. Various emulsifiers, gelling agents, and penetration enhancers are meticulously selected and incorporated to achieve the desired rheological properties and skin permeation profile. Furthermore, the study evaluates the physicochemical properties, such as pH, viscosity, spreadability, and drug content uniformity, to ensure the formulation's suitability for topical application. In vitro assessments, including skin irritation studies and skin permeation studies using Franz diffusion cells, provide valuable insights into the safety and efficacy of the emulgel. Moreover, the formulation undergoes comprehensive in vivo evaluations to assess its therapeutic potential, including anti-inflammatory activity using carrageenan-induced paw Edema model and antioxidant activity utilizing appropriate assays. These evaluations aim to validate the effectiveness of the turmeric emulgel in alleviating inflammation and oxidative stress, thereby supporting its potential use in various dermatological conditions. Physicochemical characterization of the emulgel includes assessments of pH, viscosity, spreadability, and drug content uniformity to ensure quality and consistency. In vitro studies, such as skin irritation tests and skin permeation studies using Franz diffusion cells, provide insights into the formulation's safety and efficacy profile. In vivo evaluations focus on assessing the therapeutic potential of the turmeric emulgel, including anti-inflammatory and antioxidant activities. Animal models are utilized to investigate its efficacy in mitigating inflammation and oxidative stress, thereby supporting its potential for dermatological applications. The findings of this study contribute to the growing body of research on turmeric-based formulations and highlight the promising prospects of turmeric emulgel as a novel therapeutic agent in skincare and dermatology. Overall, this study presents a systematic approach to the development and assessment of a turmeric-based emulgel formulation, offering promising prospects for its application in skincare and dermatological therapy.

  IJCRT's Publication Details

  Unique Identification Number - IJCRT24A4319

  Paper ID - 256582

  Author type - Indian Author

  Page Number(s) - l481-l504

  Pubished in - Volume 12 | Issue 4 | April 2024

  DOI (Digital Object Identifier) -   

  No Of Downloads - 33

  Author Country - India, 445204, Pusad (445204), Pusad (445204), 445204, Pharmacy All

  Publisher Name - IJPUBLICATION | www.ijcrt.org | ISSN : 2320-2882

  E-ISSN Number - 2320-2882

  Published Paper PDF : - http://www.ijcrt.org/papers/IJCRT24A4319

  Published Paper URL: : - http://ijcrt.org/viewfull.php?&p_id=IJCRT24A4319

  Published Paper PDF Downlaod: - download.php?file=IJCRT24A4319

  Cite this article

Mr. Saqlain Khan Gaffar Khan,Ms. Shabnam Rahim Sheikh,Ms. Swati Prakash Jamathe,Ms. Payal Santosh Rathod,Ms. Vishwaja Anil Mahalle,   ""GOLDEN THERAPY: CRAFTING AND ASSESSING TURMERIC EMULGEL FORMULATION"", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.12, Issue 4, pp.l481-l504, April 2024, Available at :http://www.ijcrt.org/papers/IJCRT24A4319.pdf

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