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Exploring Herbal Interventions in Antifungal Activity :A Review of Novel Botanical Treatment
Authors
MR.RAJ DINESH MORE,Dr.SUNITA OGALE
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Keywords
Plant-based antifungal properties , Azadirachta indica (Neem), Allium sativum (Garlic), Melaleuca alternifolia (Tea Tree Oil), Curcuma longa (Turmeric), Thymus vulgaris (Thyme), Eucalyptus globulus (Eucalyptus), Cinnamomum verum (Cinnamon), Capsicum annuum (Red Pepper), Artemisia annua (Sweet Wormwood), Cinnamomum cassia (Cassia), Ocimum sanctum (Holy Basil), Hydrastis canadensis (Goldenseal), Calotropis procera(king's crown), Glycyrrhiza glabra (Licorice), Silybum marianum (Milk Thistle),
Abstract
Fungal infections remain a major global health concern, particularly in immune-compromised individuals, and present a challenge in terms of effective treatment. While synthetic antifungal drugs like ketoconazole have been commonly used, their long-term use often results in adverse effects and drug resistance.[1] In contrast, herbal remedies have gained attention as alternative antifungal treatments due to their natural origin, lower toxicity, and potential to combat resistant fungal strains.[2] This review aims to explore various botanical interventions with antifungal properties, evaluating their mechanisms of action, efficacy, and safety profiles. We focus on plant species such as Neem (Azadirachta indica), Garlic (Allium sativum), Tea Tree Oil (Melaleuca alternifolia), and Turmeric (Curcuma longa), all of which have shown promising antifungal activity.[3,4,5,6] Furthermore, we discuss the synergistic effects of combining herbs to enhance antifungal potency and reduce potential side effects. This review also compares the clinical effectiveness of herbal antifungals with conventional therapies, including ketoconazole, emphasizing the need for further clinical trials to validate the therapeutic benefits of these natural alternatives.[7,8] Through this analysis, we seek to highlight novel botanical treatments as viable options for future antifungal therapies.
IJCRT's Publication Details
Unique Identification Number - IJCRT2412305
Paper ID - 273782
Author type - Indian Author
Page Number(s) - c807-c829
Pubished in - Volume 12 | Issue 12 | December 2024
DOI (Digital Object Identifier) -
No Of Downloads - 164
Author Country - India, 401305, Virar East, Virar East, 401305, Pharmacy All
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MR.RAJ DINESH MORE,Dr.SUNITA OGALE, "Exploring Herbal Interventions in Antifungal Activity :A Review of Novel Botanical Treatment", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.12, Issue 12, pp.c807-c829, December 2024, Available at :http://www.ijcrt.org/papers/IJCRT2412305.pdf
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