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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
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AN OVERVIEW OF THE RARE AND LIFE-THREATENING ADVERSE EFFECTS OF ZOLPIDEM IN THE TREATMENT OF INSOMNIA
Authors
Alana Kalam S,Dr. Subash Chandran M.P,Dr. Karthika Lal B,Dr. Prasobh G.R,Dr. Nithin Manohar
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Keywords
Key Words: Zolpidem, Complex sleep behavior, Parasomnias, Somnambulism, Sleep related eating disorder, and Suicidality
Abstract
ABSTRACT
Background: A Common sleep disorder such as insomnia is characterized by persistent problems falling asleep, staying asleep, or experiencing nonrestorative sleep that impairs functioning during the day. Regardless of the proper conditions for sleeping every night, the sleep disruptions associated with insomnia typically manifest as difficulties falling asleep, trouble staying asleep, or waking up too early. A person's quality of life can be negatively impacted by insomnia, which can lead to frequent daytime naps, difficulty focusing, an increased risk of mistakes and accidents, and lower productivity at work. A multidisciplinary strategy is recommended for the treatment of insomnia, with an emphasis on pharmacological therapy, behavioral treatments, better sleep hygiene, psychological stress management, and hypnotic treatment. In order to limit the required dosage and any associated side effects, the most successful treatments combine medication with cognitive behavioral therapy.
The most often utilized hypnotics as supplementary therapy are non-benzodiazepine ones like zaleplon, eszopiclone, and zolpidem. Zolpidem is one of these hypnotics that is most often utilized. But zolpidem has a lot of adverse effects, and the literature has a few distinctive features to keep in mind.
Objective: To carry out a comprehensive analysis of adverse events associated with zolpidem.
Method: A variety of websites, including PubMed, Google Scholar, Science Direct, Seizure Journal, Elsevier, Medscape, WHO Pharma Newsletter, Research Gate, Springer Link, and Online Library Wiley, were reviewed in the preparation of this review study.
Observation: Owing to its superior safety profile over benzodiazepines, zolpidem is one of the most often given medications for insomnia. But zolpidem usage is associated with a number of neuropsychiatric side effects that should be taken very seriously, including hallucinations, sensory distortions, delirium, parasomnias or complex sleep behaviors (CSBs), amnesia, somnambulism, sleep-related eating disorders, suicidality, etc. When prescribing a medication, medical practitioners should be cautious and mindful of its potential harmful effects.
Study Eligibility Criteria: Scholarly articles of any kind (case reports, case series, observational or interventional studies) that detail zolpidem's neuropsychiatric side effects.
IJCRT's Publication Details
Unique Identification Number - IJCRT2401604
Paper ID - 250088
Author type - Indian Author
Page Number(s) - f21-f28
Pubished in - Volume 12 | Issue 1 | January 2024
DOI (Digital Object Identifier) -
No Of Downloads - 84
Author Country - India, 695008, Trivandrum , Trivandrum , 695008, Pharmacy All
Publisher Name - IJPUBLICATION | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
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Alana Kalam S,Dr. Subash Chandran M.P,Dr. Karthika Lal B,Dr. Prasobh G.R,Dr. Nithin Manohar, "AN OVERVIEW OF THE RARE AND LIFE-THREATENING ADVERSE EFFECTS OF ZOLPIDEM IN THE TREATMENT OF INSOMNIA", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.12, Issue 1, pp.f21-f28, January 2024, Available at :http://www.ijcrt.org/papers/IJCRT2401604.pdf
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The International Journal of Creative Research Thoughts (IJCRT) aims to explore advances in research pertaining to applied, theoretical and experimental Technological studies.
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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