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EXTRACTION, EVALUATION AND STANDARDIZATION OF NASUNIN FROM PEELS OF SOLANUM MELONGENA L. PURPLE PEEL FRUITS
Authors
Jaideep Sarkar,Dr. Nitin Kumar,Dr. Pankaj Gupta
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Keywords
anthocyanin, detector, HPLC, Nasunin, retention time (Rt), Solanum melongena L.
Abstract
This study has been undertaken to investigate the determinants of stock returns in Karachi Stock Exchange (KSE) using two assets pricing models the classical Capital Asset Pricing Model and Arbitrage Pricing Theory model. To test the CAPM market return is used and macroeconomic variables are used to test the APT. The macroeconomic variables include inflation, oil prices, interest rate and exchange rate. For the very purpose monthly time series data has been arranged from Jan 2010 to Dec 2014. The analytical framework contains. This study was planned to characterize main anti-oxidant component Nasunin which is chemically an anthocyanin, from methanolic and aqueous extract of Solanum melongena L. purple coloured fruit peels. Peels of Solanum melongena L. purple coloured fruit peel were subjected to repeated maceration in acetic acid (10 %) for 24 hours and dried. Filtrate was extracted with 200 ml methanol, filtered and dried. Trifluoroacetic acid (1%) was added to this dried extract and analyzed by HPLC analysis. Peak was obtained at 25.658 and 25.649 minute that corresponds to methanolic and aqueous extract respectively. The peak strength and retention time (Rt) is inline and matches with the standard peak that confirms the presence of Nasunin; an anthocyanin component. From the results it was concluded that that peels of Solanum melongena L. contain high amount of anthocyanin component Nasunin which is considered as a strong anti-oxidant. Due to its high quantity, eggplant shows strong anti-oxidant activity which has been proven in-vitro. Nasunin is highly soluble in both media and is stable too. So this merits further investigation for anti-oxidant/ hepatoprotective activity in-vivo.
IJCRT's Publication Details
Unique Identification Number - IJCRT2006560
Paper ID - 196331
Author type - Indian Author
Page Number(s) - 4110-4113
Pubished in - Volume 8 | Issue 6 | June 2020
DOI (Digital Object Identifier) - http://doi.one/10.1729/Journal.24111
No Of Downloads - 1362
Author Country - 122001, India, Gurugram, Gurugram, India, Pharmacy
Publisher Name - IJPUBLICATION | www.ijcrt.org | ISSN : 2320-2882
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Jaideep Sarkar,Dr. Nitin Kumar,Dr. Pankaj Gupta, "EXTRACTION, EVALUATION AND STANDARDIZATION OF NASUNIN FROM PEELS OF SOLANUM MELONGENA L. PURPLE PEEL FRUITS", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.8, Issue 6, pp.4110-4113, June 2020, Available at :http://www.ijcrt.org/papers/IJCRT2006560.pdf
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