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Rice is a staple food source of many Asian countries such as India, Japan and China. Rice is the third-highest worldwide production after sugarcane and maize. Milled rice is produced annually about 480 million metric tons approximately. Mainly two kind of rice is seen. One is brown rice and another is white rice. The name of the milled rice is white rice. WHO says, By consuming white rice, some effects on human health can be seen like increased BMI, hyperlipidemia, and type 2 diabetes are more common. In white rice very small amount of vitamin A is present. This low amount of vitamin A can cause vision problem among children specially. Approximately half of the world population take daily energy from rice grains which have not sufficient levels of micronutrients and vitamins. Normally, they are deficient in iron, zinc and vitamin A. Vitamin A deficiency(VAD) is major health problem among children and pregnant woman. Night blindness and xeropthalmia are more common among children and pregnant woman due to vitamin A deficiencies in white rice. It is one of the main cause of the childhood blindness and morbidity and mortality also occur from infection in children and pregnant woman. Approximately 250 million preschool children suffer for vitamin A deficiencies and higher risk of death is seen due to malaria, measles, and diarrhea. Yearly 250,000 to 500,000 children with vitamin A deficiency become blind half of children dye within a year of losing their vision. golden rice that is genetically modified are contain sufficient amount of vitamin A which is needed for decrease the prevalence of night blindness in children specially. Globally spreading of golden rice is very slow. Asia is also suffered by insufficient spreading of golden rice. Due to insufficient spreading of golden rice across the world, blindness and another vision related problem is seen among pre-school children and pregnant woman specially. The existence, adaptation and cultivation of golden rice is very low. Golden rice 1 and golden rice 2 are sticky and grow specially in the dry land. This two varieties can be modified genetically so easily but this types of genetically modified rice can not perform well in Asian fields. Golden rice is very needed for the general population because it gives supplementary vitamin A and beta carotene which can fulfill the vitamin A requirement Specially vitamin A deficiencies is related to blindness, premature death, and xerophthalmia(thickening on conjunctiva). Golden rice is a kind of rice that is genetically modified and it can be very useful to reduce the vitamin A deficiency globally. New allergen is produced by introducing a gene into a plant of golden rice and can cause an allergic reaction to susceptible individuals. Although besides possible allergy scientists believe that GM foods is good for health. Misconception about golden rice is also present in peoples. For many different factors golden rice has not found onto the market still.