Volume 12 | Issue 3

 Abstract

Topical drug delivery system is a painless route of drug administration. There are different skin diseases and infections caused by fungus and microorganisms. which are treated with the probiotics or living microorganism which are used as active pharmaceutical agent. The purpose of writing this review article was to compile the recent literature with a special focus on a rational approaches of topical probiotic gel formulation and basic components of topical drug delivery systems. Topical applications of drugs have advantages of delivering the drug directly at the site of action and acting for a prolong period of time. Skin is one of the most widespread and important accessible organs on the human body for topical incorporation. it is the main route of topical drug delivery system. Many widely used topical probiotic products like ointments, creams and lotions have number of disadvantages as they are usually very sticky causing un-comfort to the patient after application. Moreover, they also have less spreading coefficient and need to apply with rubbing and also have the problem of stability , due to all these factors, within the major group of semisolid preparations; the use of gels has increased both in cosmetics and in pharmaceutical preparations because, A probiotic gel is colloid and it is typically 99% by weight formed by liquid material, which is immobilized by surface tension between it and a macromolecular network of fibers built from a small amount of a gelatinous ingredient present in the formation. In this revive we discus about the general Prepration and evaluation of probiotic gel

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Skin, Probiotic, gel, Topical, Novel

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The nation's economic growth is significantly influenced by the gross domestic savings. A high rate of domestic saving could result in more rapid economic growth. This study aims to examine the trend and major determinants of gross domestic savings rate in India using secondary annual data for the period 2010-2022. Data is collected from the website of World Bank. The macroeconomic variables used include foreign direct investment, inflation and GDP. The study adopts Augmented Dickey-Fuller unit root test and ordinary least square regression test to examine the long run relationship between the variables under study.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Gross Domestic Savings, GDP, Inflation, FDI, India.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Along with focusing on Kosovo, the paper looks at the parts of regional growth and stresses how the economy, society, and environment are all connected. It says that long-term economic infrastructure and fair growth are important for a region's success. This article takes a critical look at the link between political leadership and growth, focused on what happened in African states after they got their independence. The piece goes into detail about the different ideologies, development models, and problems that leaders during the Cold War had to deal with as they tried to decide what would happen to their countries. Plan in mind: modernization The piece goes into theory and shows how it can help us understand the shift from premodern to modern states. The main idea of the thesis is that good governance is important for growth and that political leadership has an impact on economic strategy. This book uses Ghana and other countries as examples to look at leadership, political governance, and economic growth in different ways. The piece talks about how different types of leadership, government structures, and economic policies can affect development outcomes. It stresses how important it is to have strong institutions and a government that includes everyone. The book looks at party and national leadership and includes a case study of Kenyan politics. The book is about Kenya's political history. It focuses on how power has grown and how different leaders have shaped development plans and outcomes. Lastly, a Case Study of Kenya is given to show the good and bad points of Kenya's growth path. This includes how parastatal institutions work, the results of constitutional changes, and what happens when there is only one party in the parliament.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Leadership, Economy, Governance, Modernisation, Development

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Nowadays it is very important to have a proper road network for the purpose of good transportation. For Few places road network is not available while the traffic is higher and enough. Pavement is generally being constructed and used for the purpose of smooth and comfort moment of the traffic. Flexible pavements will be subjected to load by wheel develop stress particles-to-particles transmit to the lower grades of layers through the granular structure. The pavement is subjected to the wheel loading action on it and the load is to be distributed to a larger area, such that the decrease in stress will occur with respect to the depth. The patch considered in this project is of Kodad to Khammam Road, Telangana. The current condition of the Kodad to Khammam Road is very much disturbed with the presence of uneven undulations as heavy loaded vehicles like moment of trucks took part. Hence, for the purpose of the fulfilment of all the above requirement factors and for the comfort moment of traffic adopted the effective design of flexible pavement. In this paper, we are enclosing the design report Kodad to Khammam Road which includes all the which comes under the project of the pavement construction.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Design, Flexible Pavement

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

This manuscript is highly suitable for publication in the journal given its alignment with the journal's aim, mission, and scope. The work addresses a critical issue in healthcare scheduling, leveraging innovative sensor technology to enhance patient care and optimize resource utilization. By streamlining the appointment booking process, the manuscript contributes significantly to the journal's mission of advancing healthcare efficiency and patient satisfaction. The novelty lies in the integration of sensor data with scheduling algorithms, offering a unique approach to improving healthcare delivery. Furthermore, the manuscript's emphasis on real-world application and tangible benefits for both patients and healthcare providers underscores its relevance and importance within the journal's domain.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Doctor Scheduling, Patient Care, AI Algorithms, Sensor Integration, Healthcare Efficiency, Resource Optimization, Appointment Management, Patient Satisfaction

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Children in India rely on family, joint family, caste, and community for support. However, weakening social structures mean outside agencies must step in when families can't provide care. Mental retardation, not a disease but a condition of delayed mental development, affects both physical and mental abilities. It slows learning, reduces understanding, and impacts speech, language, hearing, vision, and coordination. The American Association of Mental Retardation (AAMR, 1992) defines it as below-average intellectual functioning with deficits in adaptive behavior, evident from childhood. Addressing mental retardation requires holistic support to improve overall functioning and quality of life. The aim of the study is to assess the performance skills of mentally retarded children. The study was conducted with the children (30) those who were received more than 2 years training. Boys made up 70% of the sample, indicating more boys in these institutions possibly because parents were reluctant to send their daughters. The health status of other family members of mentally retarded children was examined, on paternal side 94% were found to be normal and 6% were found to be mentally retarded and on maternal side 86% were found to be normal and 14% were found to be mentally retarded. Mentally retarded children often struggle with cognitive skills, affecting their reading. The study concludes that teachers need to concentrate more on the moderately retarded children and need to introduce new parent training programs with appropriate schedule through implementation of effective mass media approach.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Children, Mental Retardation, Intellectual ability, Behavioural Assessment, Performance Skill

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

An inflammatory, autoimmune skin condition known as psoriasis can have a wide range of symptoms. Atypical keratinocyte proliferation, neutrophil activation, and T-cell (T-lymphocyte) activation are among it is principal characteristics. The growth and multiplication of keratinocytes are hindered by a range of cytokines released by T and dendritic cells. One way to treat psoriasis is with a variety of methods, such as phototherapy, systemic, and topical techniques, but there isn't a 100% cure for the condition. The anti-psoriatic drugs of today are costly, prone to negative side effects, and frequently cause the illness to recur. This review article discusses studies on natural herbs used as anti-psoriasis agents. Its objective is to offer fresh approaches to treating psoriasis. The outcomes showed that the anti-psoriatic effect of the herbal mixture was caused by various constituents. Scholars worldwide are searching for novel, safe, and efficacious psoriasis medications derived from natural resources, as the synthetic drugs currently prescribed for the condition have a connection to several unfavorable side effects.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Psoriasis, Topical treatment, Medicinal Plant, Skin, Keratinocytes.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Online marketplaces have emerged as dominant platforms in the retail landscape, revolutionizing the way consumers shop and businesses operate. This article explores the multifaceted nature of online marketplaces, highlighting their convenience, selection, and accessibility for consumers, while also addressing the challenges and concerns they pose in terms of counterfeit products, privacy, and market dominance. The discussion delves into the opportunities online marketplaces present for businesses of all sizes, leveling the playing field and democratizing access to the global marketplace. Also, the article examines the role of regulation and policy in addressing issues within the digital economy, such as consumer protection, data privacy, and competition. Looking towards the future, the article discusses emerging trends and innovations shaping the landscape of online marketplaces, including augmented reality shopping experiences, block chain-based supply chain solutions, and AI-driven personalization. This article provides a comprehensive overview of the evolution, impact, and prospects of online marketplaces, emphasizing the importance of adaptation, innovation, and collaboration in navigating the complexities of the digital marketplace

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Online Marketplaces, E-commerce, Digital Shopping Landscape

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The project aims to improve the safety and appropriateness of video content for young children by using an automated content analysis system specifically designed for YouTube. It works by comparing a variety of video elements - such as text content, visual sceneries, frame sequences, audio qualities, and color usage - to predetermined standards. Rapid frame changes, unsettling noises, excessive use of vivid colors, improper language or conversation, and disagreeable graphic components are just a few examples of the potentially hazardous or inappropriate information that the system effectively recognises and filters out. The last Filtering Module evaluates all of the analyzer outputs together, allowing for a thorough decision - making process to establish video appropriateness. This technology plays a vital part in ensuring a secure online environment for young viewers by utilizing a comprehensive approach and advanced content analysis tools, giving parents and guardians greater trust in their children's online video experiences.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Video content analysis, YouTube safety, Automated filtering, Child-appropriate content, Parental trust.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Nishakatakadi kashaya churna is a herbal formulation. Ingredients used in the drug are Haridra, Kataka, Pranati mula, Lodhra, Amalaki, Bhadarika, Meharimula, and Usira. The Ingredients in Nishakatakadi Kashaya and Nishamlaki Kashaya are having majorly Laghu, Tikshna guna, Katu rasa and Ushna Veerya and are Kapha-Vata shamaka. They act as Mootrala and has Rasayana Property1. Preliminary Physio Phytochemical studies was done using standard procedure with aqueous, chloroform, ethanol, methanol and acetone extracts of Nishakatakadi kashya churna. The ingredients of the drug has vata-kaphashamaka, dahahara, Rasayana property along with anti-diabetic effect which are mainly needed for treating Madhumeha. The inference from this study can be used as reference standard in further quality control researches.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Physio chemical analysis, Madhumeha, Nishakatakadi kashaya churna, diabetes mellitus

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Abstract In an epoch characterized by the deep integration of digital technologies into the global economic landscape, the convergence of trade in services and the digital economy emerges as a central theme in international legal discussions. This study meticulously explores the intricate tapestry of legal challenges and opportunities inherent in the rapidly expanding domain of digital trade in services. Utilizing insights from authoritative sources such as reports by the OECD, UNCTAD, and the European Parliament, the paper navigates through the complex legal frameworks that regulate this intersection. Commencing with a clarification of the conceptual framework, the research provides precise definitions of fundamental terms related to trade in services and the digital economy. It systematically scrutinizes the legal challenges arising from this dynamic paradigm, including the evolution of regulatory landscapes, concerns regarding data privacy and security, issues surrounding intellectual property rights, and the complexities of jurisdiction. This exploration serves as the foundation for comprehending the intricacies that confront policymakers, businesses, and legal practitioners in adapting to the digital age. Contrastingly, the research identifies promising opportunities within this evolving landscape. From facilitating e-commerce to fostering international cooperation and innovation, the paper illuminates avenues that can propel digital trade in services forward. Incorporating case studies and a comparative perspective, the analysis illustrates real-world examples and diverse approaches taken by different jurisdictions. Ultimately, the paper concludes with a set of recommendations designed to guide stakeholders toward a more adaptive and effective legal framework, ensuring the symbiotic thriving of the digital economy and trade in services in the 21st century. This research significantly contributes to the ongoing discourse on the legal dimensions of digital trade in services, offering a comprehensive understanding of the challenges and opportunities situated at the intersection of international trade law and the digital economy.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Keywords: Digital Trade, Regulatory Framework, Data Privacy, E-commerce Facilitation, Jurisdictional Complexity

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

In this research a bank loan dataset was utilized to assess the effectiveness of a borrower categorization model and explore machine learning methods. Different models such, as support vector machines, decision trees and random forests were. Their predictive accuracy was compared against regression benchmarks. Performance metrics were analyzed based on a ranking. The findings indicate that the Random Forest model outperforms models. Moreover, the support vector machine model exhibited performance when employing both nonlinear kernels. The study suggests that banks have the potential to enhance their models by incorporating machine learning techniques to create value.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Machine Learning, Artificial Intelligence, Supervised learning, Random Forest, Classification, Regression, TensorFlow.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The interaction between zinc oxide (ZnO) nanoparticles and Kalanchoe pinnate, a medicinal plant with various therapeutic properties, was investigation in this study. ZnO nanoparticles were synthesized and characterized through UV, FTIR, and FE-SEM. It examined, revealing size-dependent effects on plant growth and enhanced the accumulation of secondary metabolites, while higher concentrations induced cytotoxicity and oxidative stress. These finding suggested potential applications in enhancing therapeutic properties of k. pinnate extracts, emphasizing the importance of dosage control. Further studies are elucidating underlying mechanisms and optimize nanoparticle use in plant- based therapies.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Zinc oxide (ZnO), Kalanchoe pinnate.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

???????? ???? ??? ?? ??? ?? ????? ???? ?? ?? ????? ?? ??? ??? ??????? ???? ??????? ??? ?? ????? ????? ?? ?????? ??? ???- "??? ?? ?? ???? ???? ?????????????? ?????????????????, ?????, ???????, ????????, ??????????????, ????? ???????????? ?????? ????" ??????? " ????? ??? ???, ?????? ?????? ?????? ??????????????, ?????? ?? ??? ?? ???????, ????, ??????? ????? ??????? ?? ????? ?????, ??????? ?? ???????? ?? ??????, ????? ????? ???? ???? ??? ????? ???? ?? ??????????? ??? ????? ??? ???? ??????? ??? ??, ?? ??? ?? ?? ??????? ???? ??? ??? ??? ??????? ?? ?????? ?? ??????? ??? ???? ??? ?? ????? ?? ??? ??? ?? ?????? ?? ???? ?? ?????? ?? ?? ?? ??? ????? ?? ?????? ?? ?? ??????? ?? ??? ?? ??????? ???? ?????? ?? ?????? ???? ??? ????? ????? ?? ???? ???? ?? ?? ??? ??????? ???? ??? ???? ???? ????? ?? ??????? ?? ???? ?????? ?? ????? ??? ??????? ??? ??? ???????? ???? ??? ????? ????? ?? ??? ?? ???? ???? ???????? ?? ???? ????? ???????? ???????

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

??????,?????????????, ?????????????????, ?????

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

: This research represents the use of PWM (pulse width modulation) of microcontroller for controlling on direct current (DC) motor. DC motor speed is controlled using PWM technique. The signal of PWM is produced by Arduino Uno board. The Arduino Uno reads thee input from the potentiometer, which serves as a speed control knob for the DC motor. It then generates PWM signals accordingly to control the MOSFET, adjusting the motor speed. The Hall effect sensor provides feedback on the motors rotational speed, enabling the Arduino to adjust the PWM duty cycle to maintain the desired speed. Micro C language is utilized for programming and controlling the Arduino uno board. The aim of this research is to control the speed and direction of a DC motor, so that it can be used in automation systems and industrial fields. The speed of the motor is controlled by adjusting the duty cycle of the PWM signal output by microcontroller

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

DC motor, Pulse width modulation, Arduino Uno, 16*2 I2c LCD, IRF 540N MOSFET, Hall effect sensor, Potentiometer, Power supply, Feedback control, Motor speed control, Magnet sensor

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

This study explores the workforce planning approaches of successful start-ups in India. The research design employed a descriptive method and uses purposive sampling, resulting in a sample size of five participants. Data was collected using in-depth, semi-structure, guided interview, through telephonic calls and google meet video conference. Interviews were recorded with the prior consent of the participants via phone recorder and transcribed. Thematic analysis was employed to analyse the transcribed data with the aid of QDA Miner lite, a qualitative analysis software The findings revealed challenges of workforce planning, categorized into manpower planning and succession planning, and strategies to overcome challenges of workforce planning. The findings also revealed retention strategies. In addition, the findings demonstrated that succession planning is an integral part of workforce planning. Demonstrating that workforce planning goes beyond merely filling immediate job openings, it also involves nurturing internal talent, aligning it with the organization's growth and leadership requirements, and ensuring that the culture and values of the organization are preserved.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Workforce planning, manpower planning, succession planning, successful startups, workforce planning model

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

INTRODUCTION : Depressionis one of the most prevalent and common mental health illnesses. Adolescent depression may affect the teen's socialization,family relations, and performance at school, often with potentially serious long term consequences. Objectives: 1. To assess the knowledge on identification of depression symptoms in adolescents among Parents in pretest. 2. To evaluate the effectiveness of structured teaching programme on identification of depression symptoms in adolescent among parents in post-test. 3. To find out the association between the knowledge on identification of depression symptoms in adolescent among parents with their selected socio demographic variables. Methodology: Quasi- experimental with one group pre-test and post- test design was adopted for this study. The study was conducted in Nehru Nagar and Chennareddy colony, Tirupati among parents of adolescents by convenient sampling technique. The data was collected through structured questionnaire for identifying the depression symptoms and followed by a teaching programme. After 7days the post-test was administered through the same questionnaire. The post-test Mean scores of identification of depression symptoms among parents of adolescents was 17.12 and standard deviation was 2.953.The collected 't' value is 7.84 which was statistically significant at 0.01 level. The association between identification of depression symptoms in adolescent among parents with their selected socio demographic variables were statistically significant at 0.01 level respectively in post-test.Where as the demographic variable namely age of parents in years and significant association with identification of depression at 0.05 level. Results:showsthat the pre-test and post-test scores among parents of adolescents. In pre testMajority 88% of parents had inadequate knowledge, 10% of them had moderate knowledge and only 2% of them had adequate level of knowledge on identification of depressive symptoms in adolescents after post test the results were Conclusions:Identification of the depression symptoms in adolescents is very important present days majority of adolescents not expressing their needs and problems and confined to the mobiles. After providing structured Teaching programme there was significant difference in the post-test scores. The findings suggested that most of the parents have shown interest to identify depression symptoms among adolescents. There was an increased knowledge regarding early identification of depressive symptoms among adolescents.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Assess, Effectiveness, Structured Teaching Programme, Depression symptoms, Adolescents, Parents.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

This study investigates the influence of influencer marketing on Generation Z's (Gen Z) purchase decisions. With the rise of social media platforms, influencers have become powerful agents in shaping consumer behaviour, particularly among the younger demographic. Through surveys and data analysis, this research explores the extent to which influencer marketing affects Gen Z's buying behaviour, and the factors that contribute to their decision-making process.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Influencer marketing, Generation Z, Social media , authenticity, trust , engagement, brand influence.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The National Education Policy (NEP) 2020 is a government initiative aimed at reshaping the education system to adapt to the pandemic's changes. The policy aims to provide more skill-based education to students, enabling them to make informed decisions for their future. By 2025, at least 50% of learners in schools and higher education will have exposure to vocational education. Vocational education is crucial for economic growth and aims to develop industry linkages and demand-driven courses. The policy also promotes creativity and curiosity among young learners, transforming them into global resources. The policy aims to overcome the social status hierarchy associated with vocational education and integrate it into mainstream education in all educational institutions. This paper examines the current status of vocational education and its future prospects in NEP 2020.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

NEP, Vocational Education, Skilled -Manpower, Occupation, Industry, Economic Growth

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

With growing concerns about global warming and rising emissions, the asphalt industry is continuously working to reduce its emissions by lowering the temperatures at which the asphalt mixture is mixed and compacted without compromising the mix's qualities. The industry has access to a number of unique compounds that can assist in lowering the temperatures during mixing and compaction. The qualities of warm mix asphalt and combinations have been examined in studies. In order to properly coat every aggregate at low temperatures with easy workability, a binder with low viscosity must be used, and it must be produced at low heating temperatures. Warm Mix Asphalt is a low viscosity at low temperature binder technology.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Warm Mix asphalt, zycotherm, Marshal stability & Static indirect tensile strength

  License

Creative Commons Attribution 4.0 and The Open Definition