Volume 11 | Issue 7

 Abstract

Abstract Cilnidipine is a medication which are used for the treatment of hypertension (The drug Which lowers the blood pressure). The Cilnidipine is a BCS Class-II drug.Cilnidipine is a medication which are used for the treatment of hypertension (The drug Which lowers the blood pressure). The Cilnidipine is a BCS Class-II drug.It is a novel dihydropyridine calcium antagonist and its calcium antagonistic activity last for a long time more than other drugs like Nifedipine and NicardipineThe objective of the study is to get knowledge about formulation and evaluation parameters of orodispersible tablets of Cilnidipine. The objective of this work was to enhance the solubility and dissolution rate for rapid onset of anti-hypertensive action of cilnidipine.

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Cilnidipine, Orodispersible,

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The high level leap of machines into additional adroit universes has lead examiners to cultivate complex systems that can investigate human diseases through computer based intelligence instruments and techniques. One of the key investigation locales in such way is the skin ailment disclosure through picture dealing with. Unmistakable evidence of skin contaminations from the high level pictures is extending a result of complex challenges of the area. Multiclass support vector machine system. For affirmation of the diseases from the skin pictures different notable surface and repeat region features like Dim Level Co-occasions Cross section (GLCM), have been used with Assistance Vector Machines (SVM) based classifiers. Most outrageous affirmation correctnesses of 96.25%. have been seen on test set. Probably this is the essential local automated innocuous system to recognize skin diseases in India.

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Index Terms - SVM,GLCM,Machine Learning,Image processing

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Abstract: - Humans have always tried to increase their cognitive capacities through a variety of methods, including the usage of stimulants. Healthy people use prescription drugs like methylphenidate and modafinil as well as commonly available stimulants like caffeine to improve their cognitive function. For the treatment of sleep disorders such as narcolepsy, obstructive sleep apnea syndrome, and shift work sleep disorder, doctors routinely prescribe modafinil, a non-amphetamine stimulant. Additionally, research has shown that Modafinil improves cognitive abilities. Thus, it is increasingly being used by healthy people to increase alertness or lessen feeling fatigued. Patients receiving modafinil for the treatment of cognitive impairment who have psychiatric illnesses have also reported experiencing similar effects. According to clinical studies, modafinil reduces the symptoms of attention-deficit hyperactivity disorder (ADHD), schizophrenia, and significant depression in patients. When evaluating patients, psychiatrists hardly ever ask about coffee consumption. This could fail to recognize caffeine-related issues and provide effective remedies. A lot of psychiatric diseases share symptoms with excessive coffee consumption. People with eating problems frequently abuse caffeine, which has been linked to the aggravation of sleep and anxiety issues. It blocks adenosine receptors, which could increase dopaminergic activity and make psychosis worse. Caffeine has been reported to exacerbate psychotic, hostile, and anxious symptoms in mental patients. Before administering hypnotics, a routine mental evaluation of the patient's coffee use should be conducted. It is probably better to gradually cut back on consumption or gradually switch to caffeine-free alternatives than to stop suddenly. In psychiatric wards, decaffeinated beverages should be available. Background: - Many different bioactive chemicals found in caffeine, which is extensively ingested in beverages including coffee, chocolate, and soft drinks, may have an impact on disease-related pathway activity. The Diagnostic and Statistical Manual of Mental Disorders (DSM-V) now includes revised guidelines for disorders associated with caffeine consumption. The diagnosis of caffeine withdrawal is now formally recognized, and criteria for caffeine use disorder have been put forth for further research. Similar to other substance use disorders, caffeine use disorder is supposed to be characterized by cognitive, behavioral, and physiological symptoms suggestive of caffeine use despite serious caffeine-related issues. However, given the prevalence of non-problematic caffeine use, some medical professionals may find it challenging to accept the potential that caffeine consumption might lead to the same pathological behavior as alcohol, cocaine, opiates, or other drugs of abuse. When evaluating patients, psychiatrists hardly ever ask about the consumption of caffeine. This could fail to recognize caffeine-related issues and provide effective remedies. A lot of psychiatric diseases share symptoms with excessive coffee consumption. People with eating problems frequently abuse caffeine, which has been linked to the aggravation of sleep and anxiety issues. Adenosine receptors are inhibited, which could increase dopaminergic activity and aggravate psychosis. Caffeine has been observed to exacerbate psychotic, hostile, and anxious symptoms in mental IPD patients. A routine psychiatric examination of caffeine consumption drinks (coffee, soft drinks, chocolates, etc.) should be conducted before prescription hypnotics. A gradual decrease in consumption or a gradual switch to caffeine-free alternatives is likely preferable to a sudden end. There should be decaffeinated beverages available in the Psychiatry ward. Objective: - The objective of this article is to give a thorough review and analysis of the research on human caffeine withdrawal to evaluate key aspects of the disease and empirically validate particular symptoms and indicators. To evaluate key aspects of health issues and the impact of cognitive behavior, this paper publication will present a thorough review and analysis of the literature on human consumption of caffeine withdrawal. Specific symptoms and signs will be validated through empirical research. Methods: - A literature search revealed found several survey research articles and some clinical investigations on the consumption of caffeine or addiction withdrawal which fulfilled the inclusion criteria. A relevant article was found by searching for terms like caffeine abuse, CNS stimulants, and alcoholism on relevant search engines such as Google Scholar, and PubMed, Research Gate. The methodology of each study was assessed to ascertain the validity of the effects. Results: - Compared to conventional psychostimulants like amphetamine, methylphenidate, or cocaine, modafinil is recognized to have fewer or no negative side effects. As an antipsychotic or anti-fatigue agent, it is usable. Modafinil's awakening process hasn't been fully uncovered, though. According to recent studies, modafinil usage and addiction are possible. Additionally, ongoing insomnia triggers stress reactions and impedes immunological performance. Therefore, a routine psychological assessment should include a caffeine intake examination. This is crucial for individuals who struggle with substance abuse, food disorders, sleep difficulties, and anxiety. The assessment of alcohol and drug usage can readily include assessment. It is fair to inquire about the usage of over-the-counter products containing caffeine in patients who abuse drugs or have eating disorders. Conclusion: - Anyone who needs to stay awake, work late, improve cognitive reactions, or lift their mood can utilize modafinil. Users, such as cancer patients or troops in a combat zone, may already be experiencing high levels of stress. Investigating the several functions of modafinil requires a psychoneuroimmunological approach. The caffeine-withdrawal syndrome has been adequately described, and there is enough research evidence to support its inclusion as a condition in the DSM and a change to the ICD's diagnostic criteria. It would seem that caffeine is not a "pure" cognitive enhancer. Caffeine's indirect effects on arousal, mood, and focus are a major factor in how well it might enhance cognition.

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Caffeine, CNS Stimulant Drugs, Opioids, Alcohol-induced disorders, Alcohol-induced neurocognitive disorder

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ABSTRACT: In India, most of its population resides in rural areas and therefore the democracy should begin thereon in order to ensure good governance and a better functioning of democracy that we desire. To extend democracy to the rural India, the system of Panchayati Raj was established in India. The Panchayati Raj system is not a new concept and therefore is considered as one of the best ways of governance of the rural India. However, the system of Panchayati Raj, despite having derived their powers and existence from the Constitution of India, faces a lot of challenges in their day to day working because of various reasons and therefore this third tier of government has not been able to serve the purpose with which it was introduced in India.

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KEYWORDS: Panchayati Raj Institutions, Issues and Challenges.

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Management of a company's working capital entails controlling the balance between its current assets and current liabilities. The term "working capital" refers to money that a company uses to purchase immediate assets. Namely, goods in stock, accounts receivable, cash on hand, and loans and advances made to other parties. These current assets are crucial to the efficient running of the firm and effective utilisation of the fixed assets. Both liquidity and profitability may be affected by how effectively you manage your working capital. The cash available for daily operations is the engine that keeps a company running. Similar to how blood flow is vital to keeping a physical organism alive, a company's working capital is critical to keeping operations going smoothly. Without regular access to funds, it would be impossible to keep a firm afloat. It is often held that a company's profitability and liquidity levels are correlated negatively. To assist sustain future development, this study analyses the effect of steel authority of India ltd.'s working capital management practises over the fiscal years 2006 through 2016. Ratio analysis and a declaration of W.C. change are employed as research methods here

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Working Capital Management, Liquidity, Capital.

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The performance of convolutional neural networks (CNN) in the diagnosis of pneumonia and malaria, two serious illnesses, is examined in this article. The research compares the efficacy of various CNN architectures in identifying these diseases using a dataset of medical images that is openly accessible. With some architectures performing better than others, the findings show that CNNs can achieve high accuracy in the diagnosis of both malaria and pneumonia. According to the research, CNNs may prove to be an invaluable instrument for the rapid and accurate diagnosis of these diseases, which could lead to better patient outcomes and even lifesaving outcomes. Disease prediction system based on Convolutional Neural Network (CNN) (class of Deep Learning (DL) algorithm) with feature extraction and classification. Malaria spreads from the bites of mosquitoes and are transmitted to the people by the parasites. Pneumonia is an interstitial lung disease and affected to the childrens who were mostly less than two years old.

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Convolutional neural network (CNN), Malaria diagnosis, Pneumonia diagnosis, Computer-aided diagnosis (CAD), X-ray, Image segmentation, Performance evaluation, Clinical decision support

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The district of Dhemaji that lies in the north eastern part of Assam is a flood affected area. This study aims to understand the behaviour of the ground water in the vicinity of Dhemaji town in particular and in the district in general. Previous literature and data is scarce on it. An effort has been made to use the available technical data, primary data found in investigation and relevant literature reviews to infer about the behaviour of ground water in the study area. For the purpose of knowing the movement of ground water in the study area, hydrometeorology, soil characteristics, topographic slope, thickness and expansion of subsurface aquifers and hydrogeological characteristics of the area are also considered. The study reveals that ground water levels in the district are consistent over the years and long term trend of water level (rising or falling) over a period of 10 years is insignificant.

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aquifers, hydraulic gradient, ground water.

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Creative Commons Attribution 4.0 and The Open Definition

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In social accounting the focus tends to be on larger organisations such as multinational corporations (MNCs), and their visible, external accounts rather than informally produced accounts or accounts for internal use. The need for formality in making MNCs accountability is given by the spatial, financial and cultural distance of these organisations to those who are affecting and affected by itSocial Accounting has been one of the first major stepping stones in improvement in corporate social responsibility. For many organisations that undertake this process, it is the first time that attempts have been made to go beyond financial measurements.Social accounting supersedes the traditional audit audience, which is mainly composed of a company's shareholders and the financial community, by providing information to all of the organisation's stakeholders.

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Object, Needs and Present Situation

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Dr Bhimrao Ramji Ambedkar (1891-1956) was an Indian jurist, economist, politician and social reformer. He was a social revolutionary in many ways. Born into the 'Mahar' community, which was considered an 'untouchable' caste, as a child Dr Ambedkar had a first hand experience of the caste system in India and the discrimination meted out to the untouchables. Having gone through the dehumanizing experience of being ostracized by society by virtue of his 'caste', he made a firm resolve to radically alter the state of affairs. He criticized the caste system as unjust and the practice of untouchability as inhuman. He sought to awaken and organize the untouchables into a potent social and political force. He criticized the Hindu scriptures for their bias against the lower castes. He advocated the abolition of the caste system in his famous work The Annihilation of Caste. As the chief architect of the Indian Constitution, Dr Ambedkar also made sure that the practice of untouchability was banned. Dr Ambedkar has left an indelible mark on the Indian society. His untiring efforts for the upliftment of the untouchables shall be remembered for generations to come. It was largely due to his zeal that the untouchables have got legal and constitutional guarantees to live with dignity and equality.

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caste, untouchables, society, Constitution, equality

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Flyash (FA) a waste product of thermal power stations, generated problems of its disposal. Flyash has a variety of inorganic oxides and is available in finely powdered form and utilization as filler in plastics for enhancing the properties of product. In this work, fly ash treated with silane coupling agent is used as filler in Nylon-66/flyash prepared via melt blending. The comparison of the properties of composites filled with treated and untreated fly ash revealed that the composites with treated fly ash showed better reinforcing properties. Flyash treated with silane coupling agent gave better reinforcement than untreated flyash. The cracking of the particulate structure can be avoided due to adherence of flyash as particle which indicates the increase in strength of interfacial bonded. The properties of composites filled (10%FA) with treated and untreated are compared. These particulate reinforced thermoplastic composites are designed to improve the properties and to lower the overall cost of engineering plastics. In this study the effects of surface treatment with different percentage 1%, 2%, 3% on the mechanical, thermal and electrical properties of Nylon-66/flyash composites were reported.

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Nylon-66, Flyash, Coupling agent, Mechanical, SEM

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During pregnancy, the volume of blood in your body increases, so the amount of iron you need. Your body uses iron to make more blood to supply oxygen to your baby. If you don't have enough iron stores or get enough iron during pregnancy, you could develop iron deficiency anaemia. Iron can be found in two forms in foods heme and nonheme. Heme iron is only found in animal products, whereas non-heme iron is only found in plants.The recommended dietary allowance (RDA) is based on an average intake of iron 18 mg per day. However, individual requirements vary based on a person's gender and life stage. For instance, men and post-menopausal women generally require around 8 mg of iron per day. This amount increases to 18 mg per day for menstruating women and to 27 mg per day for pregnant women.

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A study to assess the effectiveness of instructional dietary module on influence of iron absorption factors on haemoglobin status in pregnant women in selected non Govt maternity hospital in Tirupati.

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WAAM is a form of Direct Energy Deposition that 3D prints metal parts using an arc welding process. Unlike other conventional AM methods, WAAM uses an electric arc to melt metal wire. The procedure is guided by a robotic arm, where the shape of the product is created on a substrate material. When the wire is melted, it is extruded into beads on the substrate. The beads bind together, forming a coating of metal. The process is repeated in a layer-by-layer fashion until the required metal part is finished. In the present study, a rectangular slab of dimensions 300 x 200 x 20 mm3 was fabricated using 4043 MIG filler wire via wire arc additive manufacturing (WAAM). The effect of welding current (heat input) on the weld microstructure and mechanical properties of 4043 WAAM alloy was investigated. Three weld joints were produced by varying the welding current from 140 to 160 A for the other welding parameters kept at constant value. The experimental findings reveal that all the weld joints were defect free and the strength of the weld decreased for the increase in the welding current. A highest joint strength of 120 MPa (119% of the base WAAM strength) was achieved in case of lower heat input(140A) weld joint. The significant strength is due to presence of more refined equiaxed dendritic microstructure and smaller size of fusion boundary. The toughness of the weld joints were 10, 11 and 12 Joules for low, medium and high heat input respectively. The toughness of the weld joints shows an increasing trend for the increase in the welding current. More softening of the weld joint has resulted in higher ductility and toughness. The results of pitting corrosion studies reveal that overall, a better and similar corrosion behaviour was achieved in all the weld joints, owing to presence of more Si in the Al matrix. The difference in the heat input and grain coarsening in the weld microstructure has attributed to variation in the corrosion resistance of the weld joints. However, the corrosion resistance of the weld joints are within the acceptable limit of the industry standards.

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CMT- WAAM, Aluminum alloys, Pore, Microstructure, Tensile properties.

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 Abstract

ఒక సమాజం సంస్కృతి, చరిత్ర, సాహిత్యం, కళలు అన్నీ భాష పునాది మీదే నిలబడతాయి. ఒక జాతికి గుర్తింపునిచ్చేది భాష. మనిషిని జంతువులనుండి విడదీసి ప్రత్యేకంగా నిలిపేది భాష. భాష పుట్టిందే ప్రజల కోసం. భాష అర్థవంతమైన ధ్వనుల సమూహం. ఆదిమ మానవుడు ఒంటరిగా జీవించిన కాలంలో తన పరిమిత అవసరాలకోసం ధ్వనిసంకేతాలు సృష్టించుకున్నాడు. సమూహంలో జీవించడం మొదలుపెట్టాక ఆ ధ్వనులు సంకేత రూపం నుండి లిపి రూపం దాల్చడానికి కొంత కాలం పట్టింది. కాలక్రమంలో భాష అనేక విధాలుగా పరిణామం చెందింది. సృష్టిలో ఉన్న మానవ జాతుల్లో, ప్రతీ భాషకు ఒక ప్రత్యేకత, సౌందర్యం ఉంటుంది. ఎవరి భాష వారికి అమృత ప్రాయమే. మన తెలుగు భాష, తెలుగు జాతి ఇందుకు మినహాయింపు కాదు. ద్రావిడ భాష అయిన తెలుగు కూడా తెలుగువారికి మధురమే. తెలుగు భాషది యుగ యుగాల ప్రస్థానం. ఋగ్వేద కాలం నుండే ఈ భాషకు ఆనవాళ్లున్నాయి. కాలగతిలో ఎందరో పాలకులు, కవి పండితులు, భాషా ప్రేమికులు తెలుగు భాషామతల్లిని పోషించి పరిపుష్టం చేశారు. తెలుగు భాషలో కనిపించే తత్సమాలు, తత్భవాలు, అన్యదేశ్యాలు అలవోకగానో అవసరంగానో ఇమిడినవే.

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అమ్మ భాషలో ఉపాధి అవకాశాలు

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This research paper examines the transformative effects of technology on the recruiting process. With advancements in technology recruitment practices have evolved significantly. The objective of this study is to provide a comprehensive overview of the impact of technology on various stages of recruitment, including sourcing, screening, interviewing, and onboarding. Additionally, the paper explores the advantages, challenges, and potential ethical considerations associated with the integration of technology in recruiting. The findings of this research shed light on the opportunities and limitations of technology-driven recruitment and offer insights for organizations to optimize their hiring strategies in the digital era. By providing a comprehensive overview of the impact of technology on the recruiting process, this research paper serves as a valuable resource for professionals in human resources, talent acquisition, and organizational leadership, helping them understand the opportunities, challenges, and best practices associated with integrating technology into their recruitment strategies.

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Adoption of Technology, HR Professionals, Perceptions

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Smart phone manufacturing and marketing is a growing sector in Maharashtra. In the recent years a domestic market for smart phone products has developed as consumers are more and more concerned for adopting new technology. Growing consumer concern for safe and healthy operations by using smart phones . Environmental awareness, especially in larger cities has shifted the demand towards alternative products. Different labeling programs for "smart phone" were established. Our lifestyle has changed in this fast paced world as compared to few decades ago. Today, more and more people are caught up in an endless cycle of buying and throwing away, seeing consumption as a means of self-fulfillment. Consumption is the reason why anything is produced. Demand towards products is driven by convenience and habit which in returned is hard to change. Truly consumers has little knowledge of the link between their purchasing choices and the environmentally consequences . he Main objective of the study to study the consumers behavioral pattern of rural consumers of smart phone Products to understand the sustainability of rural market.

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Rural market ,smart phone

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This research paper explores the opportunities, challenges, and risks associated with the digital transformation of India's money market. It provides an overview of the traditional methods and processes in India's money market and examines the impact of financial technology (FinTech) on the market. The paper identifies opportunities such as improved accessibility, efficiency, and financial inclusion, while also discussing challenges including regulatory hurdles and cybersecurity risks. Risks associated with FinTech innovations are analysed to provide practical insights. The policy and regulatory implications of digital transformation are also addressed. Overall, the paper offers a comprehensive analysis of the digital transformation of India's money market, providing valuable insights for market participants, policymakers, and regulators.

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Digital Transformation of India's Money Market

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???????? ??? ?? ????? ???????? ?????? ???????? ???? ?? ????????????? ?? ?????? ????????? ?? ?????? ???? ??? ???????? ?????? ???? ???????? ?? ??? ??? ???????? ????? ?? ????? ???? ?? ????? ??? ????? ??? ?? ?????? ???????? ?????????? ?? 100 ????????????? ?????? ?????? ?????????? ?? 50 ????????????? (?????-25 ??? ????????-25) ??? ??????? ?????????? ?? 50 ????????????? (?????-25 ??? ????????-25) ?? ????????? ??? ?? ??? ???? ??? ??? ???????? ?????? ??? ????? ???? ????? ??????? ??? ????? ???? (2005) ?????? ??????? ?????? ????????? ????? ?? ?????? ???? ??? ??? ????? ????????????? ?? ??????? ????? ?? ??????? ???? ???? ?????????? ????? ???? ??? ??? ??????????? ?? ??????? ?? ??? ??-????? ????? ???? ???? ?????? ?? ?????? ??????? ?? ?? ?????? ???????? ???? ?? ????????? ?????? ???????? ?? ????????????? ?? ?????? ????????? ??? ?????? ???? ??? ???? ??? ??? ?????? ???????? ???? ?? ????????? ??????? ???????? ?? ????????????? ?? ?????? ????????? ??? ?????? ???? ???? ????

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??????: ?????? ?????????, ?????? ???????? ???????? ?? ??????????

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This study has been undertaken to study the Malaria and treatment for prevention of Malaria.

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Antimalarials, Chloroquine, Treatments, etc.

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This study has been undertaken to compare the e-learning ecosystems universities. The paper explores the impact of e-learning among the students and faculty and examine the association between the use of e-learning and outcomes for learners and explore the policy of implications of the use of e-learning in technical universities.

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e-learning, Comparative Study, e-learning eco systems

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This research paper aims to preserve the intricate traditions and unique skills of Kashmiri traditional crafts by creating a comprehensive knowledge bank. The project aims to ensure continuity, appreciation, and innovation in these crafts, as the essence of craftsmanship is at risk of being lost due to globalization and modernization. The documentation will provide craftspeople, researchers, and enthusiasts with a resource to explore the subtleties of conventional techniques, fostering a deeper understanding and appreciation of the craft. The transfer of skills through this documentation will enable new students to carry forward the legacy. Traditional crafts extend beyond artistic endeavors and are vital components of a community's cultural heritage. The documented knowledge and techniques serve as inspiration for modern artists, designers, and artisans, stimulating innovative and environmentally friendly adaptations. The project aims to celebrate the works of artisans, pay tribute to their craft, and ensure the legacy of traditional crafts in Kashmir is preserved for future generations. By sharing this comprehensive documentation, the project aims to encourage renewed interest, inspire innovation, and contribute to the sustainable development of traditional crafts worldwide.

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Craft, Tradition, legacy, preservation, carpet weaving, pashmina, kani shawls, motifs.

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Creative Commons Attribution 4.0 and The Open Definition