Volume 12 | Issue 7

 Abstract

Drug delivery technology advancements have changed the pharmaceutical sector in recent years. One such invention is the self-emulsifying drug delivery system (SMEDDS), which offers decreased toxicity, increased therapeutic efficacy, and improved bioavailability. SMEDDS are especially helpful for medications classified as Class 2 in the Biopharmaceutical Classification System (BCS), which has low bioavailability and poor water solubility. We shall examine SMEDDS and their potential for BCS Class 2 medication delivery in more detail in this blog article. We will also discuss how SMEDDS technology is expected to develop in the future and how this could alter the landscape of medication delivery.

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SMEDDS, Bioavailability, Solubility, Permeability.

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This review highlights the different applications of nanotechnology in biomedicine, especially in such fields as interventional cardiology, cardiac implantable electronic devices, and therapeutic drug delivery. Nanotechnology is also observed to enhance diagnostic accuracy in coronary heart disease and provide novel Huntington's treatment strategies. This paper outlines the interdisciplinary features of nanotechnology en bloc with artificial intelligence, predictive analytics, and wearable devices for real-time monitoring. This concise and relatively comprehensive review has, therefore, concluded with a call for collaborative efforts for researchers and scientists working in the evolving landscape of nanomedicine.

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Nanotechnology, Biomedicine, Cardiology, Drug Delivery, Diagnostics, Huntington's Disease, Interdisciplinary, Artificial Intelligence, Wearables, Collaboration, Nanomedicine.

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Transfer learning has revolutionized various domains of machine learning by leveraging knowledge gained from one task to improve performance on another related task. In the context of predicting chemical reactions, where accurate prediction can significantly expedite drug discovery and materials science research, transfer learning offers a promising approach to enhance model performance with limited labeled data. This article explores the application of transfer learning in the domain of chemical reaction prediction using neural networks. We present a detailed study utilizing synthetic data to demonstrate the feasibility and benefits of transfer learning, along with practical implementation steps and performance evaluation metrics.

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Transfer Learning, Chemical Reaction, Drug Discovery, Neural Networks

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The use of the bibliometric analytical technique for examining Direct Marketing research is found to be non existent in the literature. The basic purpose of the study was to perform an empirical examination of bibliometric trends and patterns of all Direct Marketing -related publications in the Web of Science core collection. This study covers 617 search results from web of Science website resulting from a query for documents with titles containing the keywords, Direct marketing and marketing. Analysed parameters included document type, year of publishing, language of publication, authorship, distribution of subject category, country of publication and most-frequently cited article. VOS viewer was used for data visualization. Standard bibliometric analysis were used for presenting The growth of publications, research productivity and citation analysis. The present research aims address a significant gap in the current academic literature by utilizing bibliometric analysis to examine the landscape of Direct Marketing research. Specifically, this study focuses on conducting a comprehensive analysis of all publications related to Direct Marketing within the Web of Science core collection. A total of 617 search results were obtained by querying the Web of Science website using the keywords "Direct marketing" and "marketing" in the title of the documents. The analysis encompasses various parameters including document type, year of publication, language of publication, authorship, subject category distribution, country of publication, and the most frequently cited article. To visualize the data, VOS viewer was employed. In addition, standard bibliometric analysis methods were employed to present the growth of publications, research productivity, and citation analysis. It is worth noting that the use of the bibliometric analytical technique in the examination of Direct Marketing research has not been explored in the current body of scholarly works. Hence, this study represents a novel contribution to the academic field by providing a comprehensive overview of the publications in this area.

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Direct Marketing, marketing, bibliometric analysis

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Caste remains an important social, political, economic, cultural and psychological phenomenon in various spheres of Indian social life. The Indian caste system is seen as a hierarchical system where at the lower level are groups such as Scheduled Tribes, Scheduled Castes and Other Backward Castes who experience caste-based discrimination in almost all spheres of their lives. Social adjustment refers to the balanced performance of various social roles by an individual to achieve his or her real goals. The main objective of this study was to find out the effect of caste on social adjustment in adolescents. Keeping in mind the objective of this study, three hypotheses were formulated which are as follows: (i) Social adjustment of Scheduled Castes will be better than Scheduled Tribes, (ii) Social adjustment of Other Backward Castes will be better than Scheduled Castes, and (iii) Social adjustment of General Castes will be better than Other Backward Castes. For this, a total of 100 adolescents aged between 17 to 21 years were selected as samples from A N S College Barh (Patna) using the purposive sampling method. Data collection was done using the Mohshin-Shamsahd Adaptation of Bell Adjustment Inventory (1987). The data obtained was analyzed using various statistical tools like mean, SD, ANOVA, and p-value to get meaningful results. The result showed that on the level of social adjustment Scheduled Castes were better than Scheduled Tribes, Other Backward Castes were better than Scheduled Castes while General Castes were better than Other Backward Castes.

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Adolescents, Caste, and Social Adjustment

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Herbal nail lacquer is a type of nail polish formulated with natural, plant-based ingredients. the utilization of herbal extracts, essential oils, or other natural compounds. Onychomycosis is an infection of the nail due to fungi that include dermatophytes, non-dermatophyte molds, and yeast (Candida species). More than 90% of cases have this dermatophyte infection, which is mostly brought on by trichophyton rubrum and Candida species. Herbal nail lacquer has been designed and developed in this study for the treatment of onychomycosis. An oleuropein compound found in olive leaves has shown potential as an antifungal agent. Incorporating it into herbal nail lacquer could aim to achieve effective treatment against onychomycosis. It was anticipated that this would increase patient preference as well as potency. The nail lacquer preparation was designed by maceration for extraction and simple mixing and analyzed for thin layer chromatography, gloss, smoothness to flow, viscosity, water resistance test, drying time, and determination of antifungal studies. In this study, the formulation was prepared by using Eudragit RL-100, ethyl acetate, ethyl cellulose, dibutyl phthalate, salicylic acid, acetone, Clitoria ternatea (a coloring agent), and alpha-santalol (a smelling agent). The prepared medicated nail lacquer was evaluated for various parameters such as organoleptic characters, drying time, smoothness of flow, gloss, and water resistance that showed satisfactory results. Among all formulations, the F4 formulation was highly effective due to its good water resistance (0.05 g), quick drying time (60 s), good film thickness (0.14 mm), good viscosity (147 cp), and best zone of inhibition. From the above studies, it can be concluded that medicated nail lacquers proved to be a better tool as a drug delivery system for the transungual drug delivery of an antifungal in the treatment of onychomycosis. It can also be used for the beautification of nails with ease of application.

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Onychomycosis, oleuropein, herbal nail lacquer, anti-fungal agent

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Abstract Shiro Basti, an Ayurvedic therapeutic procedure, involves the application of medicated oils on the scalp using a special cap. This literature review aims to collate and analyse existing research on Shiro Basti, focusing on its historical significance, methodologies, therapeutic benefits, and potential applications in modern medicine. The review draws from classical Ayurvedic texts, contemporary studies, and clinical trials to comprehensively understand Shiro Basti. Historically, Shiro Basti has been used to treat a variety of neurological and psychological conditions, including headaches, migraines, insomnia, anxiety, and stress-related disorders. The procedure is rooted in the principles of Ayurveda, which emphasize the balance of body, mind.

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Shiro basti, Procedure, Ashtanga Hridaya, Ashtanga Sangraha, Keraliya chikitsa padhathi.

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The status of any social group is often assessed based on indicators such as literacy levels, education, health, and overall standard of living. Tribal women, like women in many other social groups, generally exhibit lower literacy rates compared to men. This disparity is evident in their reduced levels of educational attainment, lower enrollment rates in schools, and less frequent presence in educational institutions.

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Tribal, Status, Education, Health etc.

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Study of water quality tells about present status of unstable water for domestic use. Indiscriminate and wasteful water consumption and improper waste disposal practice have led to deterioration of both, surface water and subsurface water. Due to the pressure of human activity, urbanization and industrialization, the ground water sources are degraded gradually. Therefore pure, safe, healthy and odorless drinking water is matter of deep concern. There are many pollutants in ground water due to sewage viz, organic and inorganic pollutants, heavy metals, pesticides, fluoride etc. The purpose was to ascertain the quality of water from these sources. These were analyzed for Acidity, Alkalinity, Chloride, Hardness, pH, Fluoride and Nitrate using standard techniques in laboratory.

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Collection of Sample, Chemical Parameter testing, Health issues etc.

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This article explores a morally urgent question--"is there any human right not to suffer from severe poverty, and if yes, then does it entail any corresponding duties, either positive or negative to minimise the suffering of global poor?" It does not deny the contributions of Western moral cosmopolitans' right-based approach in addressing global poverty rather it humbly attempts to highlights some of its moral insufficiencies in addressing acute global poverty, especially in the Global South. It explores why right-based approach is a "noble lie or hollow promise" to the global poor in the absence of any plausible framework of duty. In the 'institutional approach', my primary focus will be on Thomas Pogge for the reason that he is the leading global justice theorist of our time and have done significant work in this area Having discussed problems and limitations of Thomas Pogge's institutional cosmopolitan right-based approach in addressing global poverty, I will be exploring Indian conception of human rights and how Gandhi's understanding of the relationships between rights and duties helps us in addressing global poverty in a better way.

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Human Rights, Duty, Gandhi, Pogge, Global Poverty, Institution, Cosmopolitanism, Universal Declaration of Human Rights, Moral Obligation, Sustainable Development Goals

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Telecommuting has been the latest trend in the work world. This has come into emergence due to the COVID pandemic which has caused an upheaval in work practices. It has an effect on the environment and inturn it eventually impacts the competitive advantage of the firm. Telecommuting is said to have a positive impact on the environment by way of reduced greenhouse gas emissions, less paper usage and improved quality of air and hence it was supported by most of the environmentalists. This study aims to explore the influence of telecommuting on the competitive advantage of the firm by way of environmental sustainability. The study data was collected through a systematic literature review. The results demonstrated that Telecommuting had a positive effect on the environment, ultimately enabling the organisations to gain a competitive edge over their competitors.

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Telecommuting, environmental sustainability, positive impact, emission, competitive edge.

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 Abstract

Bhariya Rajyaghatna Aani Vikashachi Ethihashik Pashvabhumi

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Bhariya Rajyaghatna Aani Vikashachi Ethihashik Pashvabhumi

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Influencer marketing refers to the collaboration between a brand and an internet influencer to promote a product or service. Artificial intelligence (AI) is a critical technological advancement of the Fourth Industrial Revolution that refers to any intelligence presented by a robot, computer, or any machine in general which is equivalent to intelligence of humans. The aim of this qualitative study is to analyse the possible uses and benefits of AI in marketing. The researchers have analysed the AI's expanding importance, as it relates to online platforms mainly influencer marketing. Additionally, the study investigates the contemporary applications of AI in social media advertising, aiming to gain a deeper understanding of the influence AI will have on the advertising and marketing sectors. Businesses use AI for various reasons including customer engagement. The researchers further investigate the integration of AI as a crucial component in advertising and its impact on digital platforms, particularly influencer marketing. To get better insight about the influence of AI on advertising sectors, the study also explores the current applications of AI in social media marketing.

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Social media, Influencer Marketing, Artificial Intelligence, Advertising, Industry 4.0

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ABSTRACT In this paper, we have tried to focus on women entrepreneurship in India. Empowerment refers to measures designed to increase the degree of autonomy and self determination in people and in communities in order to enable them to represent their interests in a responsible and self determined way, acting on their own authority. Empowerment refers both to the process of self-employment and to professional support of people, which enables them to overcome their sense of powerlessness and lack of influence and to recognize and eventually to use their resources and chances. Women empowerment principles equalities means business empowering women to participate fully in economic life across all sector is essential to build stronger economies, achieve internationally agreed goals for development and sustainability and improve the quality of life for women, men, families & communities. Across the world, educating and empowering women has proven time and again to be the catalyst for rapid socio-economic growth. Conversely, societies where women are repressed are among the most backward. In spite of Indian women have proved themselves and women (both rural and urban) have played crucial role in economic development of country.

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- Women entrepreneurship, SEWA, Need for women's empowerment, Women in corporate leadership, women entrepreneurs,

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In recent years, the use of UAVs has significantly increased due to their wide applicability in surveillance, agriculture, search and rescue, and delivery services [1]. The versatility and efficiency of UAVs make them increasingly popular, especially in specific areas such as surveillance, agriculture, search and rescue, and delivery [2]. Effective path planning is essential for enabling UAVs to operate autonomously and navigate through unfamiliar or dynamic environments [3]. Reinforcement learning has revolutionized pathfinding in complex environments by offering credible solutions to challenging navigation problems [4]. To enhance the autonomy and efficiency of UAV operations, this study introduces an adaptive learning strategy with reinforcement learning (RL) for UAV pathfinding [5]. The proposed approach aims to make the pathfinding process adaptable to changing environmental conditions by leveraging UAV experiences [6]. The system was evaluated in simulated environments, successfully navigating through challenging operational scenarios, and demonstrating the robustness of the approach and algorithm [7]. Using adaptive learning techniques and powerful deep reinforcement learning algorithms, the system effectively learns from high-dimensional inputs to achieve precise characteristics [8]. The system learns dynamically by interacting with the environment, thus adapting the pathfinding and resulting in robust performance in real-world applications [9]. The experiments conducted in simulated environments demonstrate that the proposed system is more efficient and safer compared to traditional pathfinding algorithms [10]. This research addresses a critical gap in UAV operations by presenting a novel solution that can lead to significant gains in autonomy and effectiveness across various domains. The advancement of UAV pathfinding capabilities through the development of a robust and adaptable solution for autonomous navigation in a variety of real-world applications is a key objective of this research

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Pathfinding, deep reinforcement learning, deep Q-Networks, double DQN, adaptive learning, simulation, reinforcement learning, Real-world UAV scenarios, Deep reinforcement learning algorithms in autonomous systems, traffic management systems, Environmental adaptability, Real-time decision-making, Autonomous UAV technology, deep reinforcement learning in unmanned aerial vehicles, adaptive control algorithms, and proximity

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This study investigates the significant challenges faced by Master of Education (M.Ed) students at Kerala University while preparing their research dissertations and proposes strategies to overcome these obstacles. The qualitative research design involved interviewing 15 M.Ed students to gather insights into their experiences. The analysis revealed several key challenges: time management issues, difficulties formulating research titles, inadequate supervisory guidance, etc. To address these challenges, the study recommends structured time management workshops, specialized seminars on research design, a restructured curriculum integrating statistics and research proposals early on, flexible data collection options, comprehensive training on standardization and instructional design, investment in modern technological resources, integration of statistical software training, and thorough instruction on citation practices. By implementing these recommendations, institutions can better support M.Ed in their research projects, thereby improving the standard of teaching and future educators' professional growth.

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Challenges, M.Ed students, Research Dissertation, Comprehensive training, Professional growth.

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Uterine rupture is a surgical emergency.Maternal and fetal mortality rates are very high. Early management of this complication of childbirth has mortality and morbidity associated with this complication of hildbirth. We present a case of spontaneous uterine rupture in a patient with a bi-scarred uterus at term complicated by pelviperitonitis following delayed diagnosis , treated by laparotomy in the obstetric emergency department of CHU Ibn Rochd, Casablanca.

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uterine rupture , fetal mortality , maternal mortality

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Education is a social activity. It is ultimately related with intellectual; emotional, cultural, economic and social life of human race. Education enables the individuals to seek new ideas and new ways of life. Education fashions and models the individuals as a useful social being. It promotes man is intelligence and ensures his progress The stimulus of pupils is one of the most important factors in teaching without it, there can be no learning with it, we cannot prevent pupils from learning. Believe in a push - battonage which comfort has a terrific appeal, but there is no easy road learning. The teacher can increase both of the Childs learning by appealing to the motives the child brings with him into the classroom After preparation of the questionnaire with 78 items, it was administered to 90 teachers working in secondary school of Etcherla Mandalam. The variables such as sex, qualification, designation experience, locality of the school & a management were given due consideration. The researcher want round a number of secondary school of both urban and rural areas of administer the questionnaire personally. The researcher received only 100 questionnaire, of these questionnaire received, some are not duly filled in and some are defective so the researcher eliminated the 10 defective questionnaires and tool only 90 questionnaires which are fool - proof for the present investigation. On the basis of analysis and interpretation of results, the findings are arrived at and conclusions are drawn by the researcher. From this study it is understood that the stimulus strategies impact on teaching learning process in secondary schools.

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Stimulus, Teaching Learning Process, Acquire stimulus, Environment

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Crossandra infundibuliformis, a firecracker flower native to southern India and Sri Lanka, is often used as an ornamental plant for its medicinal properties. Traditional medicine often involves various remedies using different parts of a plant, with ethnomedicine playing a role in drug discovery. Infectious diseases remain a significant cause of morbidity and mortality among humans, especially in developing countries. In recent years, resistance to antibiotics by microbes has increased, forcing scientists to search for new antimicrobial substances. Plant- based antimicrobials represent a vast untapped source of medicines. Over the last few decades, the incidence of opportunistic infections in patients treated with immunosuppressive drugs or intensive chemotherapy has increased at an alarming rate. Higher plants produce diverse chemical compounds with different biological activities, which have an important ecological role. Plant extracts have been used as alternative sources for treating fungal infections, such as Candida albicans, which are responsible for 80-90% of infections in dermatology. The phytochemical test of Crossandra infundibuliformis leaf extract revealed its antibacterial, antifungal, and anticandidal activity. By testing the inhibitory level against Candida albicans species, a topical substance could be developed against these infections. Antifungal creams, liquids, or sprays have shown effective antifungal activity in the past few years. Herbal extracts and essential oils have shown effective antifungal activity, and nanohydrogels can be applied to infected areas to reduce fungal infections. Skin acts as a protective barrier against external agents, sunburn, and body temperature, but pathogens can cause skin diseases or infections. Fungal infections are more severe because they occur on the third layer of the skin, leading to subcutaneous infections. In this study, the extract from Crossandra infundibuliformis will be collected and formulated as a cream against Candida albicans, potentially helping to treat skin infections caused by Candida albicans.

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Crossandra infundibuliformis, Candida albicans and anticandidal cream

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Purpose of this study discuss about the research publications/Productivityof science departments of Islamiah College (Autonomous), Vaniyambadi, Tamil Nadu. Objective of the study is to identify the growth rate of publications viz.Journal articles, Proceedings, Books, and research reports of the science departments after Autonomy period of the college, to know the UGC-CARE List Publications, tofind out the articles published in reputed indexed journals, and overall publications of the research departmentsMethodology adopted for this study is a systematic questionnaire prepared and distributed to five research departments for data collections. The collected data have been compared with VIDWAN-IRINS Portal also. Data analysis of the study is all the data put in to the computer excel for analysis. Simple random technique adopted for data analysis. Findings of the study reveals that Biotechnology and Chemistry departments are leading in all publications, Physics department published in reputed indexed journals and mathematics department have published more number of books suggestionswere given partial financial support will be given to the faculty members of the institution to encourage them for publication of articles in reputed indexed journals in order to increase research criteria of their institutions.Originality of the study conducted in science departments of Islamiah college (Autonomous),Vaniyambadi, TamilNadu.

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Research publications;Islamiah College;Scopus; UGC-CARE List;Indexed Journals

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