Volume 8 | Issue 6

 Abstract

A simple, rapid, selective, sensitive, accurate and precise High Performance Liquid Chromatography (HPLC) with UV detection method has been developed and validated for determination of Posaconazole in Human plasma. C18 (250x4.6mm) column was used with the mobile phase containing a mixture of Acetonitrile: Water (55:45v/v). The flow rate was 0.8ml/min and drug was monitored at 262nm. In analytical method development linearity for Posaconazole was found to be 5-100�g/ml with regression coefficient 0.9954. The accuracy and recovery was found within limit. The robustness study was performed and the method was found to be fully robust. Plasma samples were processed using acetonitrile as precipitating agent to extract drug. The linearity for Posaconazole was found to be 0.15 to 50?g/ml with regression coefficient (r2) 0.9955. The recovery was found to be 85.63%. Stability studies for freeze thaw cycle, short term stability and long term stability was done. The % CV for stability study was found within a limit.

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Posocanazole, Reverse phases HPLC, Accuracy, Precision,

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We know that a small fire in the forest eventually might lead to a forest fire in recent days we have seen many widely spread forest fires which might put wildlife in danger. Even in cities, in some industries where there is a possibility of a fire outbreak. So we propose an idea of monitoring the defined area using an aerial vehicle, i.e., a drone. If we use a drone equipped with low-cost cameras, memories, and suitable processing capabilities, it might be helpful in detecting the fire beforehand. Some of the remote sensing techniques can be used for providing much more accuracy in identifying the fire Image contains forest fires in real-time.

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UAV, RPV, GPS, IC, CSI

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Corporate social responsibility allows a business to fulfill their duties and responsibilities towards the society. It makes the company accountable not only to the shareholder but to the society as a large. Only to generate the revenue should not the objective of the corporate but it needs to think about the surrounding also for the long term survival. In April 2014, India became the first country to legally magnate corporate social responsibility. Many big and small corporate in India took the initiative and done excellent contribution to serve the nation. This paper focuses on the CSR activities of top companies who received the First national corporate award in the excellence of CSR in 2019 in the first three Categories

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Corporate Social Responsibility, inclusive growth ,sustainable development

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Students, the future of our nation and the agents of change in our societies, are flourishing and thriving in the educational institutions. They progress through a series of institutions facing changes time to time and year to year in schools, classes, teachers, peers, environment and activities. These changes may either help in developing abilities and skills to deal with the demanding situations and standards or vex or trouble them. Failure to negotiating these challenges can lead to stress and anxiety issues, retardation in educational achievements, school refusal or dropout. The aim of the present article is to determine the level of examination anxiety and academic achievement of secondary school students and to study examination anxiety in context to their academic achievement. A sample of 200 students was selected by random sampling technique from 10 Govt. and Private Secondary schools of Bhagalpur city in Bihar state. Pie diagram was plotted for graphic representation and F-value was calculated for one way analysis of variance. This study reveals that there is significant difference in examination anxiety of students of different academic achievement levels.

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Secondary school students, Examination Anxiety, Academic achievement

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Water is an essential innate resource on earth. All life including human being depends on water. Water resources are of great significance to human life and wealth and are the main insistence for the demand of drinking water, for irrigation of lands and industries. However, the pollution of the sampling area in this research is mainly from domestic pollution, which consists of some fixed pollutants, and the initial concentration of the pollutant does not fluctuate significantly. In practical applications, diverse pollution occurs, such as urban non-point source pollution, irrigation backwater pollution, livestock breeding pollution and garbage pollution. Water quality index uses variables such as dissolved oxygen, biochemical oxygen demand, acidity, alkalinity, chemical oxygen demand and chloride content, the index similarity are used to assess the water quality conditions.

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water quality index, dissolved oxygen, BOD, water pollution, water quality managemen

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Aquasomes are one of the most recently developed delivery mechanism to different sites for bioactive molecules such as peptides, proteins, hormones, antigens, and genes. Aquasomes are circular, with particle size of 60300 nm. Aquasomes are spherical particles formed from calcium phosphate or ceramic diamond coated with a polyhydroxy oligomeric film and acting as a network of nanoparticulate carriers, but rather than a pure nanoparticle. There are three layers of self-assembled structures consisting of a solid phase nanocrystalline core coated with oligomeric film adsorbing biochemically active molecules with or without modification... It is commonly used in implant preparation. Aquasomes used as RBC replacements, vaccines for viral antigen delivery and as a targeted method for intracellular gene therapy. The behavior and responsiveness of enzymes to molecular conformation made aquasomes a novel carrier of enzymes such as DNAs and pigments. This article discusses the concepts of self-assembly, the difficulties of preserving pairs of immobilized surfaces with both conformational integrity and biochemical operation. Successfully the delivery system was used to distribute insulin, hemoglobin, and enzymes such as serrati peptidase etc.

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Nanoparticulate, Nanocrystalline

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nspite of many efforts taken nowadays still security threats can be seen everywhere. And from the starting we are using just single level password authentication factors, which is not sufficient to give more security. In order to be more secure we can think of Three Level Password Authentication System. So this is an idea to implement three levels password authentication for true users. In short we can say, this is to implement three level of security. The First level password constitutes of simple text based password and this effort is taken to resist shoulder surfing attack through the text password. The Color Combination password there is basically three colors red green blue(RGB) where user can set different combination of colors according to there choice just by clicking on those colors forms the second level of authentication. Third level uses a Picture Password there at first user have to select an image in jpg format to use as an password and then user can set the password by clicking on the image in different places.These three levels of password in securing the resources from unauthorized use.

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Shoulder surfing, Grapical Authentication, Text based authentication

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The aim is to study the Interrelationship between financial markets for which the S&P BSE Bond index and the S&P BSE 100 index are used. Using the time series data of these index of the Indian bond and stock market ,the study employs various statistical and econometric tools to analyse the relationship between these two markets and concludes with a regression model explaining the relationship between bonds, stocks and gold to understand the extent to which gold is used as a substitute investment. Finally, the study concludes with bringing out the relationship between gold, stocks and bonds. The reason why gold is used in this analysis is because it is widely viewed as a haven investment when other assets fail.

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Interrelationship ,S&P BSE 100 index,S&P BSE Bond index,Indian bond and stock market, gold is used as a substitute investment

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Creative Commons Attribution 4.0 and The Open Definition

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Abstract Music is a universal language that transcends linguistic as well as cultural boundaries. It is a fundamental constituent of every culture. As such, it is a universal characteristic of human experience. Music preferences differ from person to person. These individual preferences reveal a great deal about the personality of an individual. Personality refers to the unique set of traits or characteristics that constitute an individual�s distinctive character. It encompasses an individual�s attitudes, habits, traits and the like which distinguishes him or her in relation to others. The aim of the present study was to examine the relationship between the Big Five personality traits i.e., Extraversion, Agreeableness, Conscientiousness, Emotional stability, Openness to experience and five dimensions of music namely Mellow, Unpretentious, Sophisticated, Intense and Contemporary put forward by Rentfrow, Goldberg & Levitin (2011). In order to achieve this objective a survey was carried out among 100 participants belonging to the age group of 18 to 28, of which 63 were female and 37 were male. Ten Item Personality Inventory (TIPI) and Short Test of Musical Preferences Revised (STOMP-R) were used to measure personality and music preference respectively. The sampling technique used was convenient sampling. In order to determine the association between the music and personality variables, Pearson �r� was calculated using SPSS. The findings revealed that Sophisticated dimension positively correlated to all five personality traits. The dimension called Mellow was found to be positively related to all the personality traits except emotional stability. The Unpretentious and Contemporary dimensions revealed positive correlations with extraversion, conscientiousness and openness but negative correlations with agreeableness and emotional stability. The last dimension, i.e., Intense was positively correlated to extraversion and openness but negatively correlated to agreeableness, conscientiousness and emotional stability. The implications, limitations and future directions have also been discussed in the paper.

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 Keywords

Music preference, personality, Big Five.

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The Indian economy is basically a mixed economy and its characterised as a developing market economy. It is the world's fifth-largest economy by nominal GDP and the third-largest by purchasing power parity. According to the IMF, on a per capita income basis, India ranked 139th by GDP and 118th by GDP in 2018. The sudden outbreak of the Covid-19 pandemic is an unpredictable shock to the Indian Economy. When we look upon the pre economy of India it was struck with decreasing rates of growth. With the prolonged country wide lockdown into several phases from March to June, the global economic downturn and it disrupted the demand and supply chain. The economy is likely to face the prolonged slowdown in the upcoming few years. In this paper we are going the discuss the various impacts of Covid-19 particularly on the Indian economy .

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Covid-19 pandemic, impact on various sectors, Economic slowdown, economic package, economic recovery

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When the word human rights come in light, it covers lot of things that must be highlighted by author to the people because the subject is extremely complicated. The adversary judicial system in India, which major premise is the presumption of innocence of an accused person unless proves guilty. The Indian judiciary also provides fair opportunity for the accused to defend himself and everyone have the right of social, economic and political justice but it seems that lately the Uttar Pradesh police have played the role of both judge and investigator and at the time it successfully deliver instant justice[1]. Maltreatment is the result of daily increasing to large number of death in custody. The problem of death resulting in police custody or caused due to fake encounter is still increasing which, sometimes, shakes the confidence of the people in the democratic system of the country besides creating the problem of abuse of human rights.

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Human rights violation by police

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Water is essential for life. There is only one percent of fresh water available in rivers, lakes, underground reservoirs etc. to sustain life. The mismanagement of the available water has created scarcity in many areas. Over exploitation of groundwater sources and contamination of surface and groundwater aggravate the problem of availability.The ministry of Rural Development has been implementing special area development programmes for the purpose of water harvesting in drought prone desert andrain fed areas in a participatory mode that seeks to secure close involvement of the user-communities. Thus the main aim and objective of present paper is to highlight the watershed management in Jharkhand state and to give suggestions for their proper utilization.

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Watershed, User-communities, Management

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Jordan has received the attention of international powers for decades, due to the unique characteristics it possess as a country. Especially because it is located in the heart of the vibrant Middle East, rich in immense natural resources, which makes it sit on the throne of global energy, and which further earned it civil, political and strategic importance. As it became a major corridor for land, air and sea transportation, and a focus for many global events, which increased the aspirations of the great international powers, led by the United States of America, to exist in this region, it has become the center of vital interests. After the outbreak of the Arab-Israeli conflict successive American Presidents pushed the White House to direct close attention to this region. This research will try to elucidate the military relations between US and Jordan. This paper will also focus on the factors related to the foreign policy strategy of both countries. This article will further throw light on the American military aid program to Jordan and its nature and the impact of impact of aid on US-Jordan relations will also be discussed. The paper will conclude with Observations and Findings.

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United States, Jordan, Military Aid, Foreign Policy.

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Abstract�.The major objective of the research is to explore the Buddhist ideas in manimegalai with sociopolitical background. This research is designed in a qualitative approach. Library work method is used for this study. The findings shows that the Buddhist religious ideas through Manimagalai. This Epic illustrating the Buddhist ideas, the social politics of King, the social relationship of the monarch, the politics of religious affiliation, through Manimegalai, Udayakumaran and other Characters. This way provides an opportunity to understand the religious politics of contemporary times. Buddhism has established itself in the society. The researcher confirms that this is the first article examining social politics through the character of Manimagalai in this Epic.

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Keywords�Manimegalai, Udayakumaran, Religious politics, Buddhism, Social politics, Epic.

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 Abstract

In this era, the most important thing for user as well as for an organization is network security where data of most of companies/organization is stored on clouds. So we must have to find a solution so that data must be safe during network transmission. In this regards most efficient way is to encrypt the data which we transmit from source to destination. Then at destination again decrypt the original data form encrypted data. Some of the data is more critical like some government data or military communication, banking transactions etc.. When data falls in wrong hand may leads to big devastating. In this paper, a solution for above situation a multi-level encryption is given. In this multilevel encryption, data is more secure than the conventional encryption which involves multiple rounds of encryption with same or different keys and this make the algorithm complex and more powerful.

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Cryptography, Encryption, Decryption, private-key, public-key, RSA, AES, Multilevel Encryption

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This paper investigates the behavior of axial load over concrete-filled steel tube (CFST) column and conventional reinforced concrete (RC) column. The comparative study show that the difference of the axial load capacity and failure pattern for both of the concrete-filled steel tube (CFST) and reinforced concrete (RC) columns. The experimental results and results obtained from extended three dimensional building system (ETABS) software is used for study. Concrete-filled steel tube (CFST) column with varying size and conventional reinforced concrete (RC) column were tested for better optimization of column. The experimental results shows that the concrete-filled steel tube (CFST) column has a higher bearing capacity, more effective plastic behaviour and greater stiffness.

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CFST Column, RCC Column, ETABS.

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Fuzzy random variable is a measure function from a probability space to a collection of fuzzy variables. Based on fuzzy random theory, this paper addresses Renewal theorems for a sequence of discrete fuzzy random variables .The relationship between the expected value of the fuzzy random renewal variable and the distribution functions is ?-pessimistic and ?-optimistic values of the interarrival times is discussed. Furthermore, the fuzzy random style of central limit theorem is provided. Finally, some limit theorems obtained in this paper can degenerate to the corresponding classical result in stochastic renewal process.

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Probability measure, Possibility measure, Fuzzy variable, Fuzzy random variable, Fuzzy renewal process.

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It�s certainly a difficult task to recognize, apprehend and evaluate the employability of a person. Employability is the ability of a man or woman to gain and maintain the work which he attained due to his/her capabilities. It is the competence of person to shift within the market work force and understand the capacity that is available in them. The key objective of the study is to identify the strategies or approaches to bridge the employability skill gap in higher education. The paper also highlighted the benefits of bridging the employability gap in Indian economy. The paper is based on the conceptual study. And the data has been collected from the secondary sources of information. On the contrary Education is the prime goal in 17 Sustainable Development Goals (SDGs) identified by UNO. Education immensely contributes to individual, societal, national or global happiness and prosperity that are expressed in terms of remaining 16 SDGs. Relevant training during the process of education plays a key role. Physical and mental skills are, therefore, the essential outcomes of education. Training, internship and apprenticeship are some of the ways to train the students. This paper discusses feature of these tools, takes an overview of the practice, various approaches developed by regulatory bodies like AICTE, UGC, ACAR, MCI, etc., and presents challenges before the Higher Education Institutes in India. A few recommendations such as better collaboration among the regulatory bodies, faculty training, student log-book for in-plant training, etc., have been made so as to optimally utilize training facility for enhancing employability of graduates. It is believed the paper is of interest to all concerned.

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Bridging the employability skill gap, sustainability development goals, higher education, strategy, approaches, enhancing employability

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Creative Commons Attribution 4.0 and The Open Definition

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Nowadays the need for home energy use is increasing in almost all developing countries, the growing use of smart electricity meters means that real-time information relating to residential electricity consumption is readily available.This app provides a way for the user to save energy without any big risk. This project describes the development and preliminary evaluation of an application, implemented on a mobile platform (phone or tablet). This provides both an instant overview and awareness of consumption and availability, and facility to drill down to determine detail, and potentially to control individual appliances. Project implementation is in the form of mobile application with python language, XML, PHP, SQL, HTML and using android studio software, it includes daily energy consumption details and easy payment of electricity bill, and admin controls the electricity plans through a website. Controlling home energy consumption would exist as a stepping stone to handle many environmental problems . Not only these but also problems like of shootup in electricity bills can be resolved. A user interface based app for home energy management was developed, historical home energy consumption data can be visualised via the application and basing on this end users can alter their energy consumption behaviours.. Energy consumption data over a couple of past months can be compared and variations in consumption patterns assist home owners to draw out conclusions on energy use especially reflecting on the peak hours.

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E-Saver, XML, PHP, HTML, SQL,User, Smart Home, Historical and Real Time Data.

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Currently India is facing a huge population crisis, the current population is 133.92 crore and there are predictions that India will be adding 273 million more by 2050, which will eventually make the population of the country 161 crores. Providing food security to every individual will become the challenging task and it will increase a lot more pressure on farm lands to grow more crops. But the agriculture land is decreasing at a rate of 30,000 hectares per year.Which means farmers are giving up on their agricultural land and the primary reason behind this is significant drop in the yield eventually translating into low revenue.The poor yield can be attributed to many factors such as climate change, change in the nature of soil and farmers not well equipped with information to adjust their methods to changing conditions.There is a need to make a platform which can help our farmers to take right decision on field and not to confuse them with lots of information.

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 Keywords

ANN ,RNN ,SVM, Activation function , Optimizer, Encoding, Angular 8 , Django , Tensorflow 2.0

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Creative Commons Attribution 4.0 and The Open Definition