Volume 8 | Issue 6

 Abstract

ABSTRACT Nanotechnology is a developing branch of pharmaceutical sciences wherein the particles extend in nanosizes and turn out to be more responsive when contrasted with their unique counter parts. In the past numerous years, the utilization of synthetic concoctions and physical strategies were in mould; however, the acknowledgment of their toxic impacts on human well-being and condition influenced serious world view for the researchers. Presently, green synthesis is the watch word for the combination of nanoparticles (NPs) by plants or their metabolites. This innovation is particularly compensating as far as decreasing the poisonous quality caused by the conventionally integrated NPs. In this review, we cover the perspectives by which metal particles can be integrated from green methods in the perspective of green methods utilized in the NPs combination. In the green strategies, plant metabolites and natural substances are utilized to orchestrate the NPs for the pharmaceutical and other applications. Some characterization methods are also reviewed along with applications of NPs.

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KEYWORDS: Green synthesis; Nanoparticles; Metal nanoparticles; Green synthesis of nanoparticles

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ABSTRACT: Objective: Mouth dissolving films these are novel dosage forms it comes under fast dissolving drug delivery system. It disintegrates or dissolves within the oral cavity. It does not require water for administration so that it is convenient for medications for the pediatric and geriatric patients which have the difficulty in swallowing. This research work was aimed to enhance the oral bioavailability and provide faster onset of action of Tadalafil by formulating its mouth dissolving film (MDF). Method: The MDF of Tadalafil was prepared by solvent casting method. Tadalafil it is a BCS class II and it has the oral bioavailability of about 28%. HPMC k-15, Xanthan gum, Sodium alginate (film forming agent), Glycerol (plasticizer), Tween 80 (solubilizing agent), Citric acid (saliva stimulating agent), Sucrose (sweetening agent), vanillin (flavoring agent), Propyl paraben (preservative). The formulation was evaluated for weight variation, thickness, folding endurance, drug content, disintegration time and in-vitro dissolution study stability study. Conclusion: Based on the results F2 was showed enhanced bioavailability and rapid onset of action as compared to other dosage form.

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Keywords: Tadalafil, Mouth Dissolving Film, Bioavailability.

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A huge number of projects have undergone distress due to the slowdown in Indian economy. As a result the Indian banking system has been increased in NPA (Non-performing Assets) and restructured real estate projects during the recent years. With degradation in value the distressed assets don�t produce any profit in economy. Financial distress is a trending topic these days in finance and the project�s health is very important for investors as well as management. Investors deposit money in those projects which are financially healthy as risk of default is minimized for them, while management must be able to identify causes of distress which can be controlled by taking different measures. This paper deals with the elements of project financial distress as its major signs and sources as well as it suggests ways to eliminate the consequences. This result provides an effective way to resolve financial distress by restructuring it. Restructuring a project is always a better option in comparison with liquidation if the project has undergone distress. This paper also shows that restructuring can be looked at in three broad categories: event oriented process oriented and technical oriented. This paper describes each category: their identification in live case study project and elimination process. I integrate the theory of financial distress into a real estate project initial model and examine a financial distressed phenomenon from capital market perspective and have made a restructured financial model based on different restructuring approaches- Additional loan, Debt Curtailment, Equity share, Debt-Equity tradeoff, Selling of shares and discussing about the profitability for each approach considering their pessimistic and optimistic value and the risk factors involved. Comparing all the approaches this paper suggests about the most suitable model that can be adopted for maximum profitability.

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Debt Restructuring, Financial distress, Non Performing Assets, Project financing

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A brief introduction to literary criticism and literary theory are given at the start. Then the indication of the word� Literary Criticism? and (literary theory) alongside with the root and advancement must be analyzed. Modern literary criticism is written in a variety of genres, including the article, review, survey, essay, literary profile, and bibliographical explanation. In any genre, the critic must be, in a sense, a political thinker, sociologist, and psychologist, as well as a literary historian and aesthetician. Additionally, this paper examines various critical, literary concepts and finally the conclusion is drawn by means of the review of literature indicated.

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Literary theory, criticism, traditional critical theories structuralism, formalism, feminism, deconstruction, modernism.

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To study self-control, smartphone overuse and their association among 120 late adolescent students of aged 18-21 years. For collecting and analyzing participants� data, used PMPU questionnaire (Billieux et al., 2008) for smartphone overuse and BSCS (Tangney et al., 2004) for self-control. The findings were unveiled that gender group differences were significantly found in dangerous use (t=3.91; p<.05), dependent use (t=4.71; p<.05), financial problems (t=4.19; p<.05), and self-control (t=5.62; p<.05) respectively. Stream group differences were significantly found in dangerous use (t=4.88; p<.05) and dependent use (t=2.25; p<.05) but no stream group differences were found in self-control. It was evidenced that self-control was found as a negative correlation with dangerous use (r=-.270; p<.05), prohibited use (r=-.312; p<.05), dependence use (r=-.725; p<.01), and financial problems (r=-.405; p<.01). Further it was evidenced that self-control was found to negatively and significantly predict dangerous use (R2=7.3%; F=9.30; t=-3.05; p<.01), prohibited use (R2=9.7%; F=12.73; t=-3.57; p<.01), dependent use (R2=52.5%; F=130.54; t=-11.43; p<.01), and financial problems (R2=16.4%; F=23.20; t=-4.82; p<.01) through regression analysis. This study has been concluded that students who use smartphones excessively having low self-control over their gadgets.

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Gender, Late Adolescent Students, Self-Control, Smartphone Overuse, Stream

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Profitable investment into Real Estate residential projects requires a realistic and more practical approach for evaluating its financial performance and efficiency. Uncertainty in the residential real estate has always been an issue. Till date, financial return of a residential project in India is calculated using a Discounted cash flow model (DCF) which gives a single point value (deterministic result), not including risks and uncertainties. Addressing risks and uncertainties into otherwise deterministic models avoids irrelevant and impractical financial decision and help in framing a more feasible forecasting model. The objectives of this thesis is to develop a suitable investment model for residential real estate along Dwarka Expressway, Gurugram, India using both deterministic and probabilistic financial analysis models- Discounted cash flow (DCF) model and Monte Carlo Simulation respectively. Master plan analysis and real estate market analysis led to selection of �three� different stretches on Dwarka Expressway for which forecasting investment models is developed for better investment decisions. The study divides different risks involved in the study area under five categories- economical, technological, political, legal and social risks. These identified risks are then classified under 7 quantifiable major risks categories that have an impact on the cash flow - Sales risks, Market growth risk, Leverage Risk, Development risk, Inflation risk, Interest rate risk and Taxation risk. These risks with their range of possible values are incorporated into DCF model through Monte Carlo simulation (Probabilistic Model) and a comparison is made between their financial returns for choice of investing along Dwarka Expressway.

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Residential Real Estate, Risk Identification and assessment, Forecasting Investment Model, Monte Carlo Simulation

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The two varieties of pumpkin seeds such as orange pumpkin seed (OPS) and white pumpkin seed (WPS) were analyzed with their ethanol extracts for the estimation of fatty acid components through GC-MS analysis. 37 compounds were analyzed in total in both OPS and WPS where about 19 compounds were pinpointed to be present in OPS, 25 compounds in WPS and about 8 compounds to be present common in both OPS and WPS. The peak area % concentration obtained from analysis were compared with the known peak area % concentrations of WILEY8.LIB and the results were interpreted. Some of the compounds determined to be present in higher concentration in OPS include were Propane 1,1,3-triethoxy- (6.58 %), Hexadecanoic acid, 1-(hydroxymethyl)-1,2 ethanediyl ester (9.38 %), 9,12-Octadecadienoyl chloride, (Z,Z)- propanetriyl ester, (E,E,E)- (17.59 %), 9-Octadecenoic acid, 1,2,3-propanetriyl ester � (19.19 %), Squalene (21.33 %) and those identified in WPS include Beta.-Sitosterol (5.10%), 9-Octadecenoic acid,1,2,3-propanetriyl ester (E,E,E) (5.65%), Chondrillasterol (7.30%), Propane, 1, 1, 3- triethoxy- (7.50%), Bicyclo[10.1.0]tridec-1-ene (40.55%). Among them biological activities of some of the important compounds are suggested. This study thus offers the base for using OPS and WPS as an herbal supplement.

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Pumpkin seeds, GCMS, Fatty acids

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The uses of biodiesel are increasingly popular because of their low impact on environment. However, it causes combustion problems in conventional diesel engine[CE]. Hence it is proposed to use the biodiesel in low heat rejection (LHR) diesel engines with its significance characteristics of higher operating temperature, maximum heat release, and ability to handle the lower calorific value (CV) fuel etc,. In this work, biodiesel from linseed was used as sole fuel in both versions of the combustion chamber. Engine with LHR combustion chamber was developed with ceramic coating on inside portion of cylinder head by partially stabilized zirconia of 0.5 mm thickness. The experimental investigations were carried out on a four stroke, single cylinder, DI 3.68 kW at a speed of 1500 rpm, In this investigation, comparative studies on performance parameters was made on CE and engine with LHR combustion chamber with different operating conditions of biodiesel with varied injector opening pressure and injection timing. CE showed compatible performance while LHR combustion chamber showed improved performance with biodiesel operation in comparison with pure diesel operation on CE.

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Alternate Fuels, Vegetable Oils, Biodiesel, LHR combustion chamber, Performance parameters.

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WiFi Pose Estimation, CSI, FCN, Deep learning, pi.

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Keywords: Sunderban, mangrove ecosystem, biosphere reserve, Amphan, blue carbon sink, community based conservation

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In the 21st century and specially in a democracy; people are of the opinion that everyone should have equal rights and even the law of the land provides for the same. The Indian Constitution which is regarded as the �Grundnorm� explicitly recognizes an individual�s right to equality, life and further adding right to profess any religion and protecting it through various enactments affirms the same. However, in recent years and the situation which is prevailing in India and which still persists is otherwise and an individual is forced to think that lynching is the status quo in India. The attributes behind this phenomenon ranges from religious feelings to political will where the law enforcement is proving on its futile to curb such incidents.

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Indian Constitution, Human Rights, Lynching, Democracy, Basic Structure, Rule of law, Equality, Secularism.

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Real estate sector is the second largest employer after agricultural sector in India. Hence the importance of this sector is immense for countries economic growth as well as growth of different stakeholder involved in this sector. Amongst different stakeholder present in real estate sector the investor share the maximum risk in this sector. Eventually, the investor also get the maximum financial gain. These investor could be a developer who develop real estate projects or could be any person who invest money. The purpose of carrying out this study is to find out the strategy adopted to get maximum financial benefit out of different real estate projects in India from developer�s point of view. Financial part plays important role of investment in Indian real estate. Financial return depends on many factors such as location, user Income group, project typology, government policies etc. Here, in this research financial model is prepared to calculate the financial return from specific real estate project type through case study. Now, it is important to know the importance of having this financial model for any developer. The advantages are as follows, Factors associated for real estate profit, how this factors are affecting the financial return, How this financial model indicates project profit - loss- risks through info-graphic indicators. How these factors can be modified or adjusted in the model at planning stage to avoid loss and to gain maximum return. In this research, first general real estate theories are studied, then the existing investment strategy and financial strategies are also studied in Indian context. Then optimum financial model is prepared for specific project type for maximum financial return and finally, this financial model is validated though another real estate project through case study.

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Real Estate Investment, Real Estate Challenges, Real Estate Opportunities, Real Estate Management, Real Estate Finance, Real Estate Profitability, Government Policies, SWOT Analysis, Working capital management, Financial Model, Net present Value, Cash Flow Analysis.

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Several pharmaceutical companies are currently developing bi- layer tablets for a variety of reasons like patent extension, therapeutic efficacy, marketing etc. This technology has been used to reduce capital investment. Modified tablet presses have been used to develop bilayer tablets in order to overcome problems associated with tablets like layer separation, insufficient hardness, inaccurate individual layer weight control, cross contamination between the layers, reduce yield etc. When high production output is required a modified tablet press is used.

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Bilayer, Tablet, Sustained release, Novel drug delivery system

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Herbal medicines have been used for the various diseases and disorders since ancient era. The aim of this review is to focus on the herbal remedies for anticoagulant purpose. Now a days the use of allopathic medicines is exaggerated which leads to side effects and adverse reactions of drugs. To avoid such reactions use of herbal medicine is indicated. This review explored various plants like Thymus atlanticus, Selaginella, Terminalia belerica, Tulbaghia violacae, Tridax procumbens, Porana volubilis, Panax notoginseng, Petroselinum crispum, Green and Brown algae, Grape seed, Gracilaria debilis, Ferulago carduchoram, Erigeron canadensis, Fagonia arabica, Codium fragile, Cyamopsis tetragonoloba, Bauhinia forficate, Careya arborea, Artemisia dracunculus, Angelica shikokiana, Syzygium cumini, Melastoma malabathricum, Rhaponticum acaule, Cinnamomum cassia showing anticoagulant activity. The data for this review is collected mainly from sciencediret and pubmed.

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Coagulation, Herbal anticoagulant therapy, Anticoagulant plants

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Recommender systems are the hot technology which are changing the game of online businesses. Today e-commerce business or any business which are based on websites are reshaping the world. Any online commercial business are heating a market because they are providing everything to the user or customers in one basket. E-commerce was also facing a problem when it comes with a large item sets, users has to search a product manually and user should know have about the product first to find it in the sites. But when recommender systems comes into the game people gets the relevant products recommended by a system according to their preferences. A large datasets are extracted to find the pattern or behavior of the users.

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Recommender systems, Electronic commerce, Commercial

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The essence of this research was to identify factors that affect the performance of social entrepreneurships in Ethiopia. To achieve the aim of the study a survey design with a systematic integration of quantitative and qualitative methods. In this study the required data was be collected by Questionnaire (both closed-ended and open-ended responses) with the manager or owner of 342 small- and medium-sized social enterprises. Secondary data was collected from financial and audited statements. The results of findings showed that the variables associated with individual factors, organizational resources, and organizational factors and environmental factors have a positive and significant relationship with social enterprises performance. The study recommended that for the enterprise to improve their performance, they should continuously improve personality traits and enhance firm attributes, strategies and firm specific resources; exploitation of potential of individuals ; optimum use of human and physical resources as well as effective and efficient use of financial and experiential resources; the enterprises should consider dynamic and hostile aspects of the environment planning and consider heterogeneity and competitive intensity in strategic planning.

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Ethiopia, Factor, Social entrepreneurship, Performance

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Due to huge need of water in the campus, water has to be stored and supplied according to their needs, water demand is not constant throughout the day, and it fluctuates hour to hour. In order to supply constant amount of water, we need to store water so to meet the campus water demand, water tank need to be designed. The elevated tanks are very important structures and are considered as the main lifeline elements that should be capable of keeping the expected performance during its lifespan. In this paper we have discussed about the design aspects and to calculate the entire Elevated Liquid Reservoir geometrical characteristics by taking into considerations the standard IS codes. Hence, we can revise our work based on design perspective and complete the calculated results for the tank. This project deals with the theory behind the design of liquid retaining structure (elevated circular water tank with domed roof and conical base) via �working stress method�. Initially, the project explores design of water tank for �AXIS COLEGES, (ROOMA) KANPUR� according to respective standard data provided by the college.

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Intze type Water Tank, Population, Water Demand, Elevated Storage Reservoir, and Working Stress Method

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Nutrition and health of young children is always a reason for concern in recent days. Since the past two decades a change in life style, changes in food intake, increase sedentary living and rat race for being a topper has led to increasing incidences of diseases and psychological disorders in young individuals. There are many incidences in recent days, indicating hyper tension and increased sensitivity in children that have led to their death. Many youth between the age group of 16 to 22 years have reported health issues like Anemia, low BP, hypertension, sleeplessness which have affected their performance at college. Taking into note all these situations around, a sample case study was done in which data was collected from 50 students between the age group 16 to 22. A questioner was prepared and the collected data was analyzed. It was observed that only 50% of the students consume 3 meals per day, 37% of the students were skipping their breakfast which has affected their performance at school or college. Around 53% of the students had some or the other physical activity and such students no such issues as sleeplessness. The present study has revealed that students having good food intake, having a number of small meals, and good sleeping time can excel in their education. A stress-free environment and a good support system at home are required for today�s youth to lead a healthy life.

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Nutrition and health, Health of youth, Effect of life style on health, Effect of stress on health, Food intake and health

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The market share of electric vehicles has been growing exponentially and will continue to do so. In the wake of the immense worries caused by air pollution, we must study more about electric vehicles and how we can make sure that they are available to the general public at competent prices. There are 4 main types of electric vehicles: Battery Electric Vehicle (BEV), Plug-in Hybrid Electric Vehicles (PHEV), Hybrid Electric Vehicle (HEV), and Fuel-cell Electric Vehicle (FCEV). This paper deals with the comprehensive study of electric vehicles, the various kinds of electric vehicles available right now, and being currently researched on, the recent trends and emerging technologies that could shape the future of the electric vehicle industry and the impact electric vehicles will have on the automobile market of India.

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Electric vehicle, trends, emissions, battery, impact

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Like any other transformations in this world, feminism has also been a great struggling movement. Till date, society associates women with cultural exploitation, her body and beauty standards are measured to keep the face in the industry. It�s been so long that a female is craving for her actual self, yet there is no sign of improvement in her regular societal norms and conditions. For her every walk of life she is demanded an explanatory note. Her jobs are restricted to few professions. Ever since she is a mother it becomes her duty and not a choice. Her mental status is always a funny topic to discuss. Her biological changes are made fun off and what not. Ironically, feminism is miss-communicated by these celebrities as arrogance which is not at all true. Feminism is a humanistic concern and it�s all about her liberation to raise voice against violation. The aim is not to substitute Women from Men but to give right place to her as woman as a sex and as body in society. The history of feminism consists of three waves. The wave appeared in the 19th Century. The Second wave appeared in the 1960s and 1970s and the third wave started from the 1990s to the present. The history of feminist literary criticism is extensive, from classic works of 19th Century Women authors such as George Eliot and Margaret Fuller. It was representing Women�s condition within literature; in particular the depiction of fictional female characters. Feminism isn�t about making Women strong. Women are already strong. It�s all about changing the way the world perceives that strength.

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liberation, feminism, strength and exploitation.

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