Volume 11 | Issue 5

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Keywords :- Animal models, immunomodulation, immunosuppression transplantation, translation research.

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Individuals are formed because of their emotional and psychological experiences. We are all products of our childhood experiences and parenting plays a crucial role in it. Effectively dealing with negative outcomes of past childhood incidents and learning to not let it hamper our cognitive emotion regulation strategies as an adult is important. An insight on another parenting phenomena called parentification and its relation to maladaptive and adaptive cognitive emotion regulation strategies are studied in this research. Parentification is referred as the role reversal in the parent child subsystem where the child takes up parental roles and experience pseudo maturity. Data was collected for 240 (N=240) young adults with equal number of males and females (males=120, female=120) to study the cognitive emotion regulation strategies. Findings concluded that maladaptive cognitive emotional regulation strategy has a relationship with parentification.

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Cognitive emotion regulation strategies, adaptive strategies, maladaptive strategies, Parentification, young adults

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डिजिटल विभाजन व्यक्तियों, समुदायों और देशों के मध्य सूचना एवं संचार प्रौद्योगिकी (आईसीटी) तक पहुँच और उसके उपयोग के संदर्भ में अंतर को संदर्भित करता है। इस वैचारिक अध्ययन का उद्देश्य डिजिटल विभाजन की इस परिघटना के कारणों, परिणामों और संभावित समाधानों का पता लगाना है। यह अध्ययन डिजिटल विभाजन से संबंधित वर्तमान साहित्य और सिद्धांतों का अवलोकन कर इस जटिल मुद्दे की बहुआयामी प्रकृति को उजागर करने का प्रयास करता है। अध्ययन सामाजिक-आर्थिक स्थिति, शिक्षा, भौगोलिक स्थान और बुनियादी ढांचे की असमानताओं सहित डिजिटल विभाजन में योगदान देने वाले कारकों की पहचान और यह जाँच करने का प्रयास करता है कि ये कारक आईसीटी तक पहुँचने में असमानताएं कैसे पैदा करते हैं तथा यह सामाजिक, शैक्षिक और आर्थिक विकास के लिए व्यक्तियों के अवसरों को कैसे सीमित करता है। डिजिटल विभाजन को बढ़ाने या कम करने में क्या सरकारी नीतियों और तकनीकी प्रगति की भी भूमिका होती है। इसके अतिरिक्त अध्ययन सामाजिक, शैक्षिक और आर्थिक प्रभावों पर बल देते हुए, डिजिटल विभाजन के परिणामों की व्याख्या करता है और यह जानने करने का प्रयास करता है कि आईसीटी तक सीमित पहुंच वाले व्यक्तियों और समुदायों को डिजिटल साक्षरता प्राप्त करने, डिजिटल अर्थव्यवस्था में भाग लेने, ऑनलाइन शिक्षा तक पहुंचने और लोकतांत्रिक प्रक्रियाओं में संलग्न होने में चुनौतियों का सामना क्यों करना पड़ता है। डिजिटल विभाजन को संदर्भित करने के लिए अध्ययन विभिन्न स्तरों पर संभावित समाधानों की पहचान करने का प्रयास करता है। यह समावेशी नीतियों, बुनियादी ढांचे के विकास में निवेश, निम्न गुणवत्ता की कनेक्टिविटी और डिजिटल साक्षरता कार्यक्रमों के महत्व पर जोर देता है। अध्ययन सरकारों, नागरिकों, सामाजिक संगठनों और निजी क्षेत्र के बीच सहयोग की आवश्यकता पर भी बल देता है ताकि आईसीटी तक समान पहुँच सुनिश्चित की जा सके और डिजिटल समावेशन को बढ़ावा दिया जा सके। सामाजिक समानता, समावेशी विकास और वैश्विक कनेक्टिविटी को बढ़ावा देने के लिए डिजिटल विभाजन को उल्लिखित करने व संज्ञान में लाने की तात्कालिक आवश्यकता को रेखांकित करता है।

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डिजिटल विभाजन, सूचना एवं संचार प्रौद्योगिकी, तकनीकी उन्नति, सामाजिक प्रभाव, शैक्षिक प्रभाव, आर्थिक प्रभाव, समावेशी नीतियां, डिजिटल साक्षरता कार्यक्रम, डिजिटल समावेशन

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In many experiments, it is important to be able to separate a mixture into its chemical components in order to isolate one compound or to assess the purity of the mixture. Thin layer chromatography (TLC) is one of the easiest and most versatile methods of doing this because of its low cost, simplicity, quick development time, high sensitivity, and good reproducibility. TLC is used by many industries and fields of research, including pharmaceutical production, clinical analysis, industrial chemistry, environmental toxicology, food chemistry, water, inorganic, and pesticide analysis, dye purity, cosmetics, plant materials, and herbal analysis. In its simplest form, glass plates are coated with a uniform layer of silica gel (SiO2). The dissolved sample is placed on the plate, and the plate is inserted into a screw-top jar containing the developing solvent and a piece of filter paper. When the solvent has risen to near the top of the plate, the plate is removed, dried, and visualized using UV light. Variations on this protocol are used for different purposes, including pretreating the sample, changing the sorbent, plate material, the solvent system, the development techniques, and method of detection and visualization or by coupling TLC to other techniques.

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slide thin layer chromatography mobile phase stationary phase

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Bacterial skin infections are most common amongst people, requiring significant attention for treatment and to maintain healthy skin. Some herbal plant extracts have antiseptics and activity. The paper soaps were most Frequently used hand wash preparation in this article formulate poly herbal paper soap with combination of Almond and neem and evaluate their parameter The study showed that the tested paper soaps possessed May be antimicrobial properties and they can contribute to the treatment and management of skin infections Caused by bacteria if well prepared with the appropriate plant materials to target specific causative Organisms and packaged with appropriate directions for use and storage.

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Antimicrobial activity, Skin infections, Herbal paper soaps, Medicinal plants consumers.

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The natural colorants are widely used in food, cosmetics, and other products. They are also being investigated for their potential health benefits, including their ability to inhibit cell proliferation occurs due to synthetic colouring agent There is some evidence that certain food coloring agents may be linked to cancer. For example, a study published in the journal Cancer Epidemiology, Biomarkers & Prevention found that people who ate the most artificial food coloring were more likely to develop bladder cancer. Additionally, a study published in the journal Environmental Health Perspectives found that children who were exposed to high levels of artificial food coloring were more likely to develop ADHD. This review discusses the effects of isolated natural colorants on cell proliferation in vitro. The results of these studies suggest that some natural colorants, such as anthocyanins, catechins, and curcumin, can inhibit cell proliferation in various cell types. These findings suggest that natural colorants may have potential as cancer chemopreventive agents. However, more research is needed to confirm these findings and to determine the optimal doses and delivery methods for natural colorants.

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Natural colorants, cell proliferation, Cancer, Synthetic colorants

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 Abstract

स्वामी विवेकानंद जी वैश्विक पटल पर सदैव युगदृष्टा तथा युगसृष्टा के रूप में जाने जाते हैं। ऐसे भारतीय चिंतक जिन्होंने मानव जाति को सदैव तमस के गर्त से निकालकर प्रकाश के मार्ग पर अग्रसर होने हेतु प्रेरित किया। स्वामी जी मानव निर्माण के लिए एक दिव्य पुंज की तरह सदा प्रकाशमान रहेंगे। वर्तमान परिप्रेक्ष्य में स्वामी जी के विचार मानव जीवन में प्रेरणा स्रोत की तरह ओजवान हैं जो कि मानव को अनैतिकता के भंवर से निकालकर उसके जीवन में आध्यात्मिक तथा नैतिक प्रकाश को बिखेरता है। स्वामी विवेकानंद इस युग के प्रथम विचारक हैं जिन्होंने हम सभी को अपने देश की आध्यात्मिक, नैतिक, चारित्रिक श्रेष्ठता से अवगत कराया और साथ ही साथ पाश्चात्य देशों की भी अपने भारत देश की भौतिक श्रेष्ठता से परिचित कराया। स्वामी जी को भविष्य तथा वर्तमान के मध्य की एक फलदायी संयोजक कड़ी के रूप में माना जा सकता है। स्वामी जी एक ऐसे विचारक थे जिन्होंने सदैव मानव निर्माणकारी शिक्षा की वकालत की है। उनका कहना था कि शिक्षा ऐसी हो जो मनुष्य को उसके जीवन संघर्षों के लिए तैयार करे तथा उसमें अपार संभावनाओं हेतु साहस भर दे। जिससे वह जीवन की अनगिनत चुनौतियों का पूरे सकारात्मक भाव से डटकर सामना कर सके। उनके अनुसार मानव निर्माणकारी शिक्षा के साथ-साथ उसमें मानवीय गुणों, साहस, धैर्य, आत्मविश्वास, व्यावसायिक कुशलता, अंतर्निहित पूर्णता आदि का अद्भुत समावेश भी होना चाहिए। शिक्षा वह शक्तिशाली हथियार है, जिससे मनुष्य का पुनर्निर्माण किया जा सकता है। स्वामी जी कहते हैं मनुष्य ऐसा हो जिसमें अदम्य साहस, उत्कृष्ट इच्छाशक्ति तथा मनुष्य को ईश्वर का मंदिर बनाने की क्षमता विद्यमान हो। स्वामी विवेकानंद जी के विचारों में मनुष्यता का मूल समाहित है। इनका मानना था कि सभी मानवों में ईश्वर का अस्तित्व है, इसीलिए प्रत्येक मानव ईश्वर की एक अद्भुत रचना है। गुरुदेव रवींद्रनाथ टैगोर ने भी इनके विषय में कहा है कि यदि आप भारत को जानना चाहते हैं, तो विवेकानंद जी का अध्ययन कीजिए। उनमें सभी कुछ सकारात्मक है, नकारात्मक कुछ भी नहीं। आधुनिक युग की मांग को ध्यान में रखते हुए स्वामी जी ने कहा था कि “खाली पेट धर्म नहीं होता है।“ मानव को शिक्षा प्रदान करने हेतु शिक्षा का स्वरूप कैसा हो ? प्राचीन शिक्षा वर्तमान समय में कैसे उपयोगी हो सकती है? प्रस्तुत शोध पत्र मानव मूल्यों, मानव निर्माण पर आधारित शिक्षा का स्वरूप तथा स्वामी विवेकानंद जी के ओजस्वी विचारों की वर्तमान परिप्रेक्ष्य में उपादेयता पर प्रकाश डालता है।

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बीज शब्द- स्वामी विवेकानंद, शिक्षा दर्शन, मानव निर्माणकारी शिक्षा

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Human Trafficking is one of the rigorous problem in India especially women and girl child were in this, about 80 percent of human trafficking across world in done for sexual exploitations and the rest for bonded labor. In Asia,India is considered as the focal pointof this crime.International market has been created sex as well as cheap labour. In this way, most of the women are basically marginalized sections of society and they are facing many problems from the side of their family members, domination of husband, harassment, domestic violence and more girl child in a family etc. and also the main route cause is poverty. In India most of the trafficking women are coming from urban areas and have no proper education, The Government welfare programmes related to women are nor get in right way because of lack of education, So, they were influenced by human traffickers' for job opportunities, employment and so on. So, the researcher has been conducted a study on the health conditions of trafficking women in Guntur district , Andhra Pradesh, India. The present study is only on focused on their socio- economic, health and psychological issues with the appropriate research methodology.

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Trafficking Women, Socio, health and psychological issues, Government Programmes,

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Cloud computing is a paradigm shift in the way we access, collect, and manage data and applications. With the rise of the Internet, cloud computing has become a ubiquitous computing model. which allows users to access computing resources such as servers, storage and applications over the Internet. In this architecture, users can access these resources on-demand, pay only for what they use, and scale their usage up or down based on their needs. The internet computing provides such numerous benefits like as Flexibility, Scalability, Cost-effectiveness, and Increased efficiency. This abstract provides an overview of cloud computing and its benefits, discusses its various deployment models, and highlights some of the key challenges in the adoption of cloud computing. It concludes with a discussion on the future of cloud computing and its potential to transform the way we do business and access technology. In this article, we will investigate some of the safety issues that are associated with using cloud computing. across various domains such as multi-tenancy, scalability, and uptime. Additionally, we will explore established security methodologies and strategies for ensuring a protected cloud environment. This document aims to provide Professionals and experts with insights into the different security risks, models, and tools available.

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Cloud Security, Cloud Computing, Security Techniques, Security Threats, Cloud Security Standards.

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Reinforced cement concrete (RCC) as a construction material has come into use for the last one century. In India, RCC has been used extensively in the last 50-60years.During this period, we have created large number of infrastructural assets in terms of buildings, bridges, sports stadium etc., which are lifeline for the civilized society. These have been created with huge investment of resources. We cannot even dream of recreating such assets out of limited national resources. It is there more essential to maintain them in functional condition. Since, deterioration of RCC is a natural phenomenon and has started exhibiting in large number of structures, a systematic approach is needed in dealing with such problems. Identification of the causes of deterioration and consequent repair/rehabilitation strategy at optimum cost needs a scientific evaluation and solution. Concrete constructions require proper care in the form of regular maintenance If buildings remain for several years without proper attention then, various factors like water stagnation, paint peeling, plaster break- off, fungus growth, cracking of external surfaces will affect the building. Penetration of moisture into reinforced concrete components promotes corrosion process and further damages the concrete cover. It has been observed that the deterioration phenomena of RCC are not realized by majority of practicing civil engineers. As a result, the factors considered necessary for durability of RCC buildings are many times not given due importance during construction and/or during maintenance. The durability provisions have been given emphasis in the revised Code of Practice on Plain and Reinforced Concrete' (IS: 456-2000). In the international scenario also, deterioration of CC had been drawing attention of the practicing civil engineers for quite some time. They have accordingly, made certain advancement in the field of protection, repairs, rehabilitation, strengthening and retrofitting of the existing RCC structures taking advantage of the advancement in the materials science, more particularly the polymer science. The knowledgeas UPV, rebound hammer, pH, carbonation, corrosion test, delamination, and cover metre tests were undertaken.

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Introduction,future scope, methodology

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"Health has evolved over the century as a concept from individual concern to a worldwide social goal and encompasses the whole quality of life. Today health is recognized as a fundamental right of human being". The mosquito borne diseases cause more deaths than any other communicable diseases in India. It has been highlighted that out of 500 samples, it was found that 256(51.2%) half of the samples found to have average level of knowledge. Further on, 188(37.6%) had good level of practice and lastly, 56(11.2%) had been poor category of practice score the comparison between pre interventional and post- interventional practice score. Pre interventional practice scores was assessed that among 500 samples, 342(68.4%) had average practice score, followed by 121(24.2%) had poor practice while 37(7.4%) had good level of practice. After video assisted module out of 500 samples, it was found that 256(51.2%) half of the samples found to have average level of knowledge & 188(37.6%) had good level of practice and lastly, 56(11.2%) had been poor category of practice score. The data shows that Video assisted module improved practice regarding prevention of dengue among adults. the analysis and interpretation of data collected to generate the possible solution of the research study. It mainly include the descriptive statistical analysis of demographic characteristics and the features of subjects, assessment of pre-test and post-test knowledge, effectiveness of video assisted module and associations of pre-test knowledge and practice with selected demographic variables were observed

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M.P.: Madhyapradesh, H: Hypothesis, df: Degree of freedom

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Thai traditional medicine has relied on the herbal ball to treat a variety of ailments, including acne. However, using the herbal ball in actual practise is difficult and time-consuming. The goal of this research was to create a gel using a herbal ball extract in order to improve the effectiveness of the herbal ball as an acne therapy. The Benchalokawichian cure and powdered stem bark were combined to create a herbal ball. To get the extract, the herbal ball was heated and squeezed.Based on a carbomer gel, gel form ulations containing the herbal ball extract at strengths of 0.1, 1 and 5% w/w were created. The herbal ball extract had minimal bactericidal concentration, antioxidant, and antiactivity. With an inhibitory zone value of 5, the 5% w/w gel formulation demonstrated antibacterial ef ficacy against P. acnes. This suggests that the gel formulation that was produced may be useful for treating acne. The use of herbal ball extract in the form of gel ought to be easier to use than the conventiona l way of using herbal balls.

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Gel, Topical, Antiacne, Herbal, Cosmetic use.

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In India cricket is the most popular sport. The required electricity for the stadium which is generated by conventional source is very costly. So, by making it more energy efficient and environmentally will be suitable for masses. This research paper focuses on the design and implementation of a solar tracking system for a cricket stadium which aims to maximize the energy output of the solar panels installed on the stadium roof by tracking the sun's movement throughout the day. The solar tracking system is powered by a combination of solar panels and batteries, ensuring that the system operates even during power outages. With the implementation of such solar tracking system, its output is 32% higher than fixed solar panel. The paper concludes by highlighting the potential for similar solar tracking systems to be implemented in other sports stadiums and large-scale facilities

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Solar tracking system , Atmega328 Microcontroller, IoT Internet of things,

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One of the leading causes of death is lung cancer. The majority of the time, a delayed diagnosis and subsequent therapy result in lung cancer death, claims a study. In a very small percentage of cases where lung cancer is discovered early, it can be treated. Thus, improving the patient's survival depends greatly on the early identification of lung cancer. Based on generative adversarial networks (GANs), this study suggests an approach to lung segmentation accuracy that is more accurate. We may employ GANs and capitalise on their capacity to change images to achieve image segmentation. The ability of generative adversarial networks (GANs) to synthesise globally and locally coherent images with object shapes and textures that are indistinguishable from genuine images is one of the fundamental issues still to be solved. In this study, we offer lung segmentation using U-net, one of the popular deep learning architectures for image segmentation [1]. Therefore, this process is required to remove extra information from lung CT pictures. Based on a limited image collection that includes a few hundred manually segmented lung images, our network accurately segments the data.

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U-NET Architecture , Lung Image Segmentation, Image Processsing

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Distillation is a very ancient method of separation used for splitting a mixture of liquids into its individual components. It is speculated that distillation has been around from 2000 BC and its origins lie in the Mesopotamian region. Distillation is based on thermodynamics, and liquid separation is achieved by adding and withdrawing heat. Distillation was a batch procedure used to produce drinks and alcohol prior to the industrial revolution. The primary goal of the work is to improve the physical performance of the batch distillation column pilot plant. Performance of the available plant can be categorised as either an increase in product quality, such as purity, a decrease in batch operating time, or an increase in the amount of product extracted from feed. The goal of the work is to combine these three potential outcomes. Advanced control techniques, such as MPC, will improve product purity while shortening the time needed for the procedure. The steps in the design of a distillation column are as follows: Specify the level of isolation necessary: establish product requirements. Choose the batch or continuous operation type and operating pressure. Decide whether to use plates or packing as the contacting device. Calculate the number of equilibrium stages and the stage and reflux requirements. Column dimensions: diameter and actual stage count. Create the plates, distributors, and packing supports for the interior of the column. Internal fittings and the vessel's mechanical design

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Distillation, Batch processing, Product, Reflux, MPC.

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Creative Commons Attribution 4.0 and The Open Definition

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This literature review is aimed at understanding "Sustainable Living", and factors which impact Sustainable living, Carbon footprint being the major one. It will help us to understand how carbon emissions affect a wide array of regions ranging from food to transport and construction among others. The reduction of carbon emissions should be discussed more often since major industries take irresponsible actions regarding their carbon footprint hence causing damage to sustainability. This study includes reviews of articles about carbon footprints over different carbon emitting sources.

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Creative Commons Attribution 4.0 and The Open Definition

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Green House Gas (GHG), Carbon Footprint (CF), Emission, Sustainable, Environment.

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Creative Commons Attribution 4.0 and The Open Definition

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A regulatory process by which a person gets authority to launch a drug in the market, is known as drug approval process. ANDA is an application for a US generic drug approval for existing licensed medication or approval drug. Drug analyst in regulatory agencies around the world keep up the responsibility of evaluating whether the research data support the safety, effectiveness and quality control of new drug product to serve the public health. Every country has it's own regulatory authority, which is responsible to implement the rules & regulations and issue the guidelines to regulate the marketing of the drug. This article focus on the drug approval process in different Countries like India, Japan and US -FDA.

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Creative Commons Attribution 4.0 and The Open Definition

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US-FDA, India, Japan, ANDA, Regulatory Approval Processes

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Creative Commons Attribution 4.0 and The Open Definition

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"Health has evolved over the century as a concept from individual concern to a worldwide social goal and encompasses the whole quality of life. Today health is recognized as a fundamental right of human being". The mosquito borne diseases cause more deaths than any other communicable diseases in India. The distribution of the samples as per their pre- interventional knowledge score. It has been analyzed that among 500 adults, most of the samples, 342(68.4%) had average knowledge regarding prevention of dengue fever. Secondly, it has been depicted that 145(29%) had poor level and only 13(2.6%) had good level of knowledge regarding prevention of dengue fever. The distribution of the samples according to the post- interventional knowledge score regarding prevention of dengue fever among the adults. It has been critically analyzed that among the 500 samples, majority of the samples, 245(49.0%) were in good category of the knowledge. It was followed by 183 (36.6%) had been in the excellent category. Further on, 70(14%) were found in the average category and only two (0.4%) were in the poor category level It shows comparison between pre interventional and post- interventional Knowledge score. Pre interventional Knowledge score is Poor (0-7) 29%. Average (08-15) 68.4% Good (16-23) 2.6%.excellent (24-30) 0% after video assisted module Poor (0-7) 0.4%. Average (08-15) 14% Good (16-23) 49%.excellent (24-30) 36.6%. This data shows after video assisted module improved knowledge regarding prevention of dengue among adults. Hence, the video assisted module has been a good strategy to improve the cognition among the prevention of dengue fever among the adults.

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Creative Commons Attribution 4.0 and The Open Definition

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M.P.: Madhyapradesh, H: Hypothesis, df: Degree of freedom

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Creative Commons Attribution 4.0 and The Open Definition

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Kidney disease also increases risk of having heart and blood vessel disease. These problems may happen slowly over a long time. Early detection and treatment can often keep chronic kidney disease from getting worse Research Approach : In this study Pre-experimental research approach was selected to assess the effectiveness of Self instructional modules on knowledge and attitude regarding home care of post hemodialysis patient. Research Design: In this study pre-experimental one group pre test and post test only research design was used. Sample: The sample of present study consists of 60 patients with post hemodialysis. Sampling Technique: In the present study non probability purposive sampling technique is used. Sample Size : In the present study 60 patients with post hemodialysis in B.M. Shah Hospital, Bhilai(C.G.) It was conducted among 10 samples for a period of one week. The pilot study was conducted from 22/08/2022 to 04/09/2022 to assess the feasibility of the study and to decide analysis plan. The pre-test result of this study showed that the hemodialysis patients had inadequate knowledge and attitude. Self instructional modules was given for 45 minutes and the post-test was conducted on the 7thday. The post-test score showed a significant increase in the knowledge and attitude regarding the home management of hemodialysis patients. The pilot study revealed that the present study was feasible to conduct. Reliability:- Items of the tool were coded and the reliability was calculated by using "Split half method". The score was 0.09. This tool was highly reliable.

Licence: creative commons attribution 4.0

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Creative Commons Attribution 4.0 and The Open Definition

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H: Hypothesis, df: Degree of freedom

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Creative Commons Attribution 4.0 and The Open Definition

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Due to a paucity of data and efficient statistical methodologies to characterise complex natural processes and anthropogenic activities, it is difficult to understand spatial and temporal patterns of groundwater geochemistry at the regional scale over a long period of time. This study employs hierarchical cluster analysis to investigate the clustering behaviour of groundwater quality parameters. The study utilises a comprehensive dataset comprising groundwater samples collected from different locations of Niali and Kantapada block. It helps to know about the Genesis and distribution of ground water flow in a geological formation. The groundwater quality parameters considered in the analysis include chemical constituents such as pH, electrical conductivity and major ions. From pipers trilinear diagram it is revealed that the dominant hydrochemical facies of Niali and Kantapada are Ca - Mg - CI - SO4 (I) followed by Ca - Mg - HCO3 (IV). Which simply mean alkaline earth dominating alkalis and strong acid dominating weak acids. These parameters are indicative of water quality and can provide insights into the potential contamination sources and hydrogeochemical processes governing the groundwater system. Groundwater plays a crucial role in sustaining ecosystems and fulfilling human water needs. Understanding the spatial variability and clustering patterns of groundwater quality parameters is essential for effective water resource management and environmental planning. Hence the changes in groundwater geochemistry in the study area may be a short- or long-term disintegration or decomposition process of rock and/or anthropogenic activities. We also noticed indirect ion exchange reaction between host rock and water along flow system.

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Creative Commons Attribution 4.0 and The Open Definition

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Geochemistry, Hydrogeochemical facies, Chloro alkaline Index (CAI), Cluster analysis, Dendogram.

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Creative Commons Attribution 4.0 and The Open Definition