Volume 12 | Issue 3

 Abstract

Oral administration is the most convenient and preferred means of any drug delivery to the systemic circulation.Controlled-release drug delivery systems (CRDDS) provide drug release at a predetermined, predictable and controlled rate required for therapeutic effect. To improve the solubility and bioavailability of poorly water soluble drugs, solid dispersions is the most frequently used. Amongst solid dispersions, lipid based carriers had a higher success rate in enhancing the bioavailability of Class II drugs (Furosemide), one such promising group of carrier is Phospholipid (soyalecithin). The aim of the present work was to prepare phospholipid solid dispersion of Furosemide (PLD) with soy lecithin in different ratios using solvent evaporation method. The prepared PLD4 was used to prepare core tablets (F1-F5) using polymers HPMC K4M & E15, which were further subjected to compressed coat (C1-C5) using sodium bicarbonate, PVP K 30 and HPMC E5. Post-compression parameters of Furosemide tablets were evaluated. Formulation F4 core tablet was optimized having drug release of 93.31% in 12 hrs, drug content was 99.50%, floating lag time 16sec with floating time 12 hrs. Among compressed coated floating tablets of Furosemide, C3 has shown 93.31% release with zero order release pattern.

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 Keywords

Solid dispersion, soyalecithin, floating lag time, higuchi equation, compressed coated

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 Abstract

pharmacotherapy benign prostatic hyperplasia includes various options with differing side effect profiles, including alpha blockers, 5-alpha reductase inhibitors, phosphodiesterase inhibitors, anticholinergics, and beta-3 agonists, each with unique efficacy and safety considerations.

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Benign prostatic hyperplasia , alpha blockers ,5 alpha reducters inhibitors,phosphodiesterase inhibitors,anticholinergics ,beta 3 agonists

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It is vital to conserve energy for evolution, growth, and survival as it is a component of day-to-day life as well as increase in demand. India as a nation developing country and require focusing on energy. Energy conservation with proper methodology like energy audit can be proper solution. The paper focuses on the importance of energy conservation by considering the loads of a forging plant having a contract demand of 450 kVA with HT1 connection considering the energy consumed by the present loads and recommending energy efficient technology.

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Energy, Forging

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Satisfaction and success in life is directly linked to the vocational success. The present study aims to compare the vocational Interest of Muslim adolescents and to study the effect of their family background factors on vocational Interest. For this purpose 100 Muslim Adolescent from Dist. (U.S.N.), Uttarakhand were selected through simple random sampling.Vocational Interest Record developed by Bansal V.P. and Srivastava D.N. was used. The collected data was analyze using t- test and ANOVA test. Result revealed that boys were found slightly more interested than the girls in agriculture area. Whereas girls were shown more interest in household jobs than boys. Muslim boys and girls in reaming areas namely : artistic, executive commercial, literary, scientific and social field found insignificant result at 0.05 level of significance at df 98. No significance difference found in the vocational interest of rural and urban Muslim adolescents.

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Key words: Vocational Interest, Muslim Adolescent

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Abstract: Background of the study: Through these years chemotherapy nurses have mastered clinical expertise in areas which contribute to patient care. Research Methodology: An evaluatory research approach was used to find out the effectiveness of VAT on safe handling of cancer chemotherapeutic drugs for GNM nursing students is pre experimental one group pre-test post-test design. Dependent variables: Knowledge level of nursing officers cancer chemotherapeutic drugs. Independent variables: Video teaching programme. Data collection: Demographic variables and structured knowledge questionnaire was developed. Results: Descriptive and inferential statistics. The effectiveness of VAT was identified using frequency and percentage. Paired 't' test was used to find out the significant difference between the pre-test and post-test knowledge scores and the mean post-test knowledge scores (32.was higher than the mean pre-test knowledge scores (16. 2). The computed 't' value is18.87 .is higher than the tabled value t 49 at p<0.05 .level of significance the association between pre-test knowledge scores and selected variables were calculated using Chi square test. Conclusion : The nurse carries personnel responsibility for nursing practice and for maintaining competence by continuous learning. Video teaching programme enhance the knowledge of GNM nursing students .

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Key words: Effectiveness, Safe Handling, Cancer Chemotherapeutic Drugs, Nursing Officers, PTP.

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This study examines methods for forecasting cryptocurrency prices, focusing on Bitcoin, Ethereum, and other major cryptocurrencies. We analyze historical data, market sentiment, technical indicators, and fundamental factors to build predictive models. Additionally, we assess the influence of external factors like regulations and global events. Our research aims to enhance understanding of cryptocurrency market dynamics and provide actionable insights for investors and researchers.

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 Keywords

Cryptocurrency, Price Prediction, Bitcoin, Ethereum, Forecasting, Machine Learning, Sentiment Analysis, Technical Indicators, Fundamental Analysis, Market Dynamics, External Factors.

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Studies on neurology ward patients have demonstrated elevated prevalence of mental health disorders. Previous reports have indicated a wide range of prevalence rates (39% to 64%) of psychiatric morbidity in neurological patients, with a notable poor identification rate of mental diseases in this population. This study aims to investigate the hypothesis that the psychiatric morbidity in neurological patients may influence their disease behaviors. The research, conducted at the Government General Hospital in Guntur, India, involved 58 neurological patients who completed the self-administered Illness Behaviour Questionnaire (IBQ). The IBQ, a 62-item measure with dichotomous (Yes/No) responses, was utilized to assess various components of sickness behaviors. Importantly, interviewers were unaware of the IBQ subscale ratings. Among the participants, 31 met DSM-IIIR criteria for a mental condition, and 25% (8 patients) were diagnosed with depressive disorder (major depressive disorder or dysthymia). The study's findings suggest that neurological patients with psychiatric morbidity tend to exhibit more severe disease behaviors compared to their counterparts without psychiatric morbidity. If confirmed, these results emphasize the importance of considering the impact of mental morbidity on specific aspects of sickness behavior in the development of treatment approaches.

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Mental disorder, Psychiatry, Neurology, Depression

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To back the conveyance of persistent care, apportioning of Medicine and stock administration are vital issues. In specific, it screens and records the Patients points of interest. The Quiet will be allotted with unique-id after the enrollment completes. PMS shows the patient's individual points of interest and wellbeing reports/ therapeutic E Medicine. In conjunction with Automatic alert system i.e. the remainder will be given to Pharmacist on stock coming to least level. Electronic endorsing (e-prescribing) permits Pharmacist to arrange and send medicines electronically based on the medicine -id. It stores all charging information for apportioned medicine.

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Pharmacy Management System (PMS), Electronic Pharmacy Record (EPhR), Electronic prescribing.

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: High-frequency trading (HFT) is a complex and fast-paced form of automated trading that uses sophisticated algorithms to exploit tiny price discrepancies in the market. While HFT has increased market efficiency and liquidity, it has also raised concerns about fairness and potential manipulation. This research explores the evolution of HFT, its impact on market dynamics, and the challenges it poses for regulators and policymakers. By examining cases like the Italian and Swedish stock markets, the study highlights the need for adaptable regulations that can ensure a stable and fair financial system in the face of evolving automated trading practices. The knowledge gained from this research can inform policymakers, market participants, and investors as they navigate the ever-changing landscape shaped by HFT.

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High Frequency Trading, Liquidity, Implied Volatility

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College management systems play a critical role in managing the daily operations of educational institutions. With the advent of web-based systems, the management of colleges has become more efficient and effective. This survey paper provides a comprehensive overview of college management systems developed using PHP, a widely-used server-side scripting language. The paper presents an analysis of ten recent IEEE reference papers and a base paper on college management systems using PHP. This survey paper examines the different approaches, methodologies, and contributions of these papers, and identifies the factors that make an ideal college management system.

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College Admission System, Research Paper, Technical Writing, Science, Engineering and Technology.

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This study has been undertaken to investigate the use of technology on the name of ICT that it can improve the learning skills and abilities of the students including the learning outcome of the content and imagination power of the students. Through ICT, images, videos can easily be used in teaching to students providing them a better understanding on what they had to be thoughted by the teacher. ICT in education improves engagement and knowledge retention, when ICT is integrated into lessons. Students become more engaged in their learning practices. This is because along with the education it also provides more fun and enjoy while learning, but this reduces the self-time of the child as without going over its own thoughts and feelings it is feeded by pre-written contents.

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ICT, young children, electronic gadgets, education, emotions.

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This research paper examines the transformative impact of Artificial Intelligence (AI) on the contemporary workforce. Through a review of literature and real-world examples, it explores how AI is reshaping job roles, talent management, and skill development. While AI offers new possibilities for efficiency and productivity, it also raises ethical and social concerns. The paper forecasts the continued evolution of AI in the workplace and emphasizes the need for proactive measures to maximize its benefits while addressing its challenges. In summary, this research highlights the dynamic interplay between AI and the workforce, urging stakeholders to navigate this evolving landscape with foresight and responsibility.

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Artificial intelligence (AI), workforce, Social Impact

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Abstract: Social media is a kind of a platform, where people can share their ideas, beliefs, knowledge, talents, creativity and many more. Initially it was a medium for people to communicate with each others. But gradually it became a tool for the political parties to influence the voters by spreading negative pictures of their opponent parties and a positive picture of their own party. With the help of social media they can share their agendas, policies and political thoughts. Social media includes Facebook, Instagram, X (formerly known as Twitter), WhatsApp, YouTube, Koo etc. But in this research the author will specifically emphasize on the three main social media platforms. They are Facebook, Instagram and X (formerly known as Twitter). By analyzing these three platforms the author will try to find out how Social media shapes the voting behavior of people of Assam especially in the Assam Legislative Assembly Election, 2021 and the author will try to find out how political parties use these platforms to fulfill their political interests and political campaigns.

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Social media, voters, Political Campaigns, Politics, voting behavior

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The main focus of this paper was to design and develop the Mechanism for robotic arm for lifting an object. The robotic arm was designed with four degrees of freedom and programmed to accomplish accurately simple light material lifting task to assist in the production line in any industry. three dimensional (3D) printing method is used in this project to fabricate the components of the robotic arm. Therefore, it provides more precise dimensions and huge time and cost- saves in fabrication. The robotic arm is prepared with 4 servo motors to link the parts and bring arm movement. The Arduino, an open-source computer hardware and software, is applied to control the robotic arm by driving servo motors to be capable of modifying the position. Wireless control was done by using a smart phone with an android operating system through a Bluetooth module. The robotic arm was under testing and validating its performance and the results indicate that it can perform the lifting task properly.

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3d printing, AutoCAD, Bluetooth, servo motor etc.

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Mobile phones have become an integral part of our daily lives. While they have various advantages, excessive use can be harmful, especially for strenuous activity such as sports. This study examines mobile phones' impact on physical sports, as well as the ramifications for high school and college students. Since the Covid-19 Pandemic, we have been providing students with mobile phones so that they may study and learn online through internet portals. However, the majority of students use their cellphones to access social media, which has an impact on both their professional academic lives and their personal health. It is affecting the health of college students. As they are participating in sports actively, there are lot of health issue arising.

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Social Media, Physical Education, Health

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Millions of people each year suffer from periodontitis, sometimes known as gum disease. The periodontium (the soft tissues and bones that surround and support teeth) is harmed by periodontitis, a serious gum infection. Generally, the gums and bones that support the teeth become infected by bacteria found in dental plaque. If left untreated, periodontal conditions can have a serious negative impact on one's health. The last ten years have seen a global shift in the prominence of herbal and Ayurvedic medicines, with ramifications for both medicine and business. In pharmaceutical formulation, herbal excipients play a significant role because they are non-toxic and compatible. Since ancient times, herbal remedies have been used extensively around the world. Both doctors and patients now realize their superior therapeutic value because they have fewer side effects than modern pharmaceuticals. The purpose of the current essay is to provide a comprehensive overview of the current approaches used in the development and use of conventional herbal treatments. This review article provides an overview of the most recent research on the biological effects of natural products including Aloe Vera, Azadirachata indica, Ocimum sanctum, Punica granatum and other significant herbs on the treatment of different periodontal disorders.

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Herbal remedies, dental plaque, gingivitis, and periodontitis

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This project focuses on the extraction and characterization of mucilage from Tamarindus indica, commonly known as tamarind. Tamarind mucilage is a polysaccharide-rich substance with potential applications in various industries, including food, pharmaceuticals, and cosmetics. The extraction process involves optimizing parameters such as temperature, solvent type, and extraction time to achieve maximum yield and quality of mucilage. The extracted mucilage is subjected to thorough characterization using various analytical techniques. Physicochemical properties, such as viscosity, solubility, and moisture content, are assessed to understand the material's behavior and potential applications. Structural elucidation is performed using techniques like Fourier-transform infrared spectroscopy (FT-IR) and nuclear magnetic resonance (NMR) to identify functional groups and molecular composition. Furthermore, the rheological properties of tamarind mucilage are investigated to evaluate its suitability for specific industrial applications. The project aims to provide valuable insights into the potential uses of tamarind mucilage as a natural and sustainable resource, contributing to the development of eco-friendly products and processes. The findings of this research may open avenues for the utilization of tamarind mucilage in various sectors, promoting sustainable practices and reducing dependency on synthetic alternatives.

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Tamarindus indica, Mucilage extraction, Characterization, Viscosity, Solubility.

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The paper investigates various security measures within the realm of the Internet of Things (IoT). It is expected to cover strategies aimed at enhancing the security of IoT systems, with a primary focus on protecting devices, networks, and data from potential threats and vulnerabilities. The content likely includes discussions on encryption methods, authentication approaches, secure communication protocols, and other pertinent security measures specific to IoT. Through a comprehensive survey and analysis of these security strategies, the paper aims to offer valuable insights into effective approaches for addressing security challenges associated with IoT.

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Internet of Things (IoT), cloud computing, RFID research, Ad Hoc Network, and Hybrid wireless networks.

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Diabetes mellitus stands as one of the most prevalent non-communicable maladies globally. India is confronted with an array of challenges in the management of diabetes, encompassing a mounting incidence of this ailment across urban and rural domains, a prevailing dearth of public awareness regarding the disorder, inadequate medical infrastructure, elevated treatment costs, suboptimal glycemic control, and a surge in the occurrence of diabetic complications. Subcutaneous injections serve as a modality for administering insulin therapy in diabetes management, allowing for up to four administrations daily. Nonetheless, the long-term employment of insulin therapy is beset by detriments to patient outcomes due to challenges associated with patient adherence and the intrusive nature of its delivery mechanism. While type 1 diabetes is observing an upward trajectory, the focal point of the diabetes epidemic is primarily anchored in type 2 diabetes mellitus, which represents over 90% of all diabetes cases. Type 2 diabetes, a perilous and pervading chronic ailment, emerges from a multifaceted interplay of genetic predisposition, environmental factors, and supplementary risk elements, including obesity and sedentary lifestyle behaviors

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Diabetes mellitus; Classification; Diagnosis; Cause; Treatment

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It has been demonstrated that herbal tea has several benefits. Tisanes are another name for herbal tea. A common and important element of social and cultural gatherings is tea. It is a preparation that strengthens immunity, maintains vitality, and regenerates cells. It eases worry, weariness, tension, and exhaustion. The beverage referred to as "herbal tea" is prepared with medicinal plants, herbs, and spices. Because of its medicinal and healing qualities, it is drunk all over the world without the need for caffeine. It can be purchased loose or in tea bag form. Herbal tea can be made by decoction or infusion with a total amount of water, or it can be diluted to an appropriate consistency and steeped for a predetermined amount of time.Natural bioactive substances like carotenoids, phenolic acids, flavonoids, coumarins, alkaloids, polyacetylenes, saponins, and terpenoids can be found in abundance in herbal teas and beverages. Herbal teas are concoctions prepared from the roots, leaves, fruits, and flowers of vibrant factory corridor plants. Herbal tea has antimicrobial and anti-inflammatory qualities, among other medicinal properties. Popular herbal teas include peppermint, ginger, ginseng, black, green, chamomile, and cinnamon teas. Most herbal teas can have one primary herbal component, or a combination of herbs used to achieve a certain goal. With herbal teas, connoisseurs can sample a wide range of flavors and possible health benefits.This study investigates the preparation and assessment of herbal teas, looking at the harmonious combining of therapeutic herbs to produce tasty and useful drinks.

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 Keywords

:Tisanes, Camellia sinensis, Fermented, Phytochemicals, Antioxidant

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