Volume 11 | Issue 1

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KEYWORDS- Garbhsanskar, Garbhini Paricharya, Foetus, Pregnancy,Masanumasik Chikitsa

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The present review article's main goal is to enlighten readers about Vildagliptin, a new oral anti-hyperglycemic drug that inhibits the dipeptidyl peptidase-4 inhibitor (DPP-4) and increases the release of insulin from Langerhans beta cells, lowering blood sugar levels. Vildagliptin is a medication with a short half-life (1.32-2.43 hours), making it a good candidate for the manufacture of sustained release tablets to extend the therapeutic effect. By applying the direct compression method and varying the ratios of polymers and excipients, sustained release tablets will be created. The mass, tapped, angle of repose, Carr's index, and Hausner's ratios of the powder will assess. The hardness, thickness, friability, weight fluctuation, drug content, and in vitro release of the produced tablets will assess. Utilizing 0.1N HCL as the dissolution medium, a dissolution research should be conducted using a USP type-II dissolution apparatus. The formulation's drug release methods include zero order, first order, the Higuchi model, and the Korsmeyer-Peppas model.

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Vildagliptin, Sustained Release Tablet, Direct Compression, Dissolution Study, Kinetics Study

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The present study was conducted to explore the relationship between Occupational Stress and Job Satisfaction among college level physical education professionals of Chhattisgarh and Uttar Pradesh. Samples of 160 physical education professionals were selected. To measure occupational stress, scale developed by Dr. A.K. Srivastava and Dr. A.P. Singh was used and to measure job satisfaction, scale developed by Dr. Amar Singh and Dr. T.R.Sharma was used. The result of the study showed that a significant correlation between occupational stress and job satisfaction among college level physical education professionals of Chhattisgarh and Uttar Pradesh. On the basis of the result of the study, it can be concluded that there is negative and strong relationship between the occupational stress and job satisfaction.

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Key words: Occupational stress, Job satisfaction, Physical Education Professionals, College level.

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Every Organization Seeks to Find Means by Which It Can Get What It Wants with The Limited Resources at Its Disposal. Firms Seek to Adopt the Concept of Budgeting and Budgetary Control. Budgeting Is a Useful Tool That Guides Firms to Evaluate Whether Their Goals and Objectives Are Actualized.

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Budget, Budgetary Control, Organization, Effects.

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Church buildings in India are an important pedigree of social identity and continue to have a consort presence in public life. Concurrently religious practices have evolved, and it has become ostensible that church buildings not just only represent a religious heritage, but also equally importantly a historical heritage. church buildings play an indispensable role in the urban and social structure of the town and surrounding landscape. Not only for the fellowships but also for the wider local community, these church buildings are provenance of great pride. Due to their architectural form, location, and often their sheer size, Church buildings contribute to creating a local disposition and character. Therefore, the deviant nature of religious heritage compared to other heritage is mainly explained by the strong emotional connotations people have with the presence of the building. Even church buildings without cultural-historical or monumental value might have a great emotional value for local residents. This makes religious organizations, governments, private parties, interest groups, and residents often convinced of the importance of preserving this cultural heritage. The historical significance of Church buildings in the Bundelkhand region can be honored as comely, historic, scientific, and social value for past, present, and future generations. They can be referred to as incomparable valuable heritage that can take us into the aperture of the forgotten colonial past. Understanding the significance of these historic buildings and the magnificent architecture on them depicts the unrevealed stories associated with this architecture, they narrate why it has become significant to conserve them.

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a) Indo-Gothic b) Rearward c) Wilderness d) Voussoir e) Hip-Roof f) Facade

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suffering, wife, daughter-in-law, violence, patriarchy.

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Parkinson's disease is a neurological disorder characterized by progressive loss of dopaminergic neurons in substantia nigra. The death of dopaminergic neurons causes primary motor symptoms and other complications. In this review, we highlight several risk factors that appear to play a role including genes, environmental triggers, mitochondrial damage, oxidative stress, impairment of protein degradation pathways, aggregation of misfolded proteins, some lifestyle factors and we have also focused on how COVID-19 has changed the lifestyle of PD patients during the lockdown. Approved treatments for PD such as dopamine agonist, MAO-B inhibitors, COMT inhibitors, and anticholinergics are focused on preventing worsening of symptoms along with different side effects, to counteract these limitations herein we highlight some alternative measures such as herbals, surgery, and device aided stimulations which may help to provide a better life of PD patients with improved compliance. These herbal alternates can be substitutes due to their structural diversity possing different therapeutic properties such as anti-inflammatory, antioxidant, anti-apoptotic, and others.

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Parkinson's disease, mitochondrial dysfunction, pathophysiology, herbals, device aided stimulation

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The Preston Curve has served as the foundation of global health policy for a very long, with significant attention given to its implication that income has a causal effect on life expectancy. Our research sets to evaluate this relationship with the modern data of SAARC Countries by incorporating econometric recommendations

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Preston curve, life expectancy, GDP per capita

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Modern technology, Positive effects of learning new technology, Negative effects of learning new technology, Artificial Intelligence, Blockchain.

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In last decade of time, people are heavily relied on social media environments like Twitter, Facebook, Blogs, Whatsapp, Instagram etc., to know about the news about different concepts, famous people, products and services. Most of the people utilized these environments for sharing their opinions on different entities. Some people are spreading false or fake information in these environments to misguide the users. Identification of people who spreads the fake information becomes one important challenge for research community. PAN competition conducted a competition on fake news spreaders detection task in 2020. Several researchers proposed solutions for finding the authors who spreads the fake news in social media environments. In this work, we proposed an approach for fake news spreaders detection by using different feature selection algorithms. The content based features like words are most important features to differentiate the writing styles of fake news spreaders and real news spreaders. The identification of important words for experimentation is very important to improve the accuracy of fake news spreaders detection. In the proposed approach, feature selection algorithms are used for identifying most relevant words or features for experimentation. The identified features are used for representing the documents as vectors. These document vectors are trained with machine learning algorithms for generating the classification model. This model is used for predicting the accuracy of proposed approach as well as for predicting whether new author is fake news spreader or real news spreader. The PAN 2020 competition fake news spreader detection dataset is used in this experiment. Two machine leaning algorithms such as random forest and support vector machine are evaluating the accuracy of proposed approach. The proposed approach attained best accuracy for fake news spreader detection when compared with most of the approaches.

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Fake News, Fake News Spreaders Detection, Feature Selection Algorithms, Machine Leaning Algorithms

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Venlafaxine Hydrochloride, Sustained Release Tablet, Manufacturing Technique for Sustained Release Tablet, Evaluation Parameter of Sustained Release Tablet.

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In the human history of India, civilized civilized life is recorded in the Vedas. At that time, it was time for all-round development for women. She was on a par with men for serious subject studies like Vishal Drishtikona's Tattva Dhyana on Swatantra Jeevan. It seems to be the age to build up some of the later mythological histories. In that context, the lack of freedom, equality, education facilities for her degraded the status of women. Let this depravity seen in the time of Ramayana and Mahabharata be re-emerged in Buddhism and Jainism in the name of Kanti Shravare Yogina Suvalivura. But then Bandha Smritikar again increased the discrimination of men and women and dominated the women's society. Manu Maharishi said that women are worshiped and goddesses live where women are worshiped. Thus, in the concept of objectivity and individualism, known as the eyes of women's society, the history of public life and its values, epics are more useful for the study of women's history. Therefore, in the way women's society, which is the main part of family society, has developed, the new fact of women's society has been highlighted in this article by observing the Mahabharata.

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Mahabharrta, Women, women's society, Female Characters, Deities

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The rapid development of information technology has resulted in changes in purchasing transaction activities by consumers which were originally carried out by visiting stores and then switching to e-commerce. According to Reportal Digital Indonesia data for 2020, of all internet users in Indonesia, 80% of them use e-commerce to make buying and selling transactions. The transition of business from physical stores to e-commerce can further encourage business competition because it is easier for consumers to switch choices to online stores. Service quality on e-commerce platforms will ultimately determine consumer satisfaction and trust as well as consumer behavior in the future, repurchase intentions, site revisit, and word of mouth. This study aims to determine the effect of overall e-service quality on customer satisfaction and customer trust in Shopee e-commerce. Determination of customer satisfaction, and customer trust on repurchase intention, word of mouth, and site revisit are then tested to get a more complex structural model. This study uses a quantitative approach where research data is collected through online questionnaires. The research sample of 170 respondents was taken randomly using snowball sampling. The analytical method used in this study is SEM (Structural Equation Modeling) with the AMOS 22.0 program. The results of data analysis show that overall e-service quality has a significant effect on customer satisfaction and customer trust. Customer satisfaction has a significant effect on repurchase intention, word of mouth, and site revisit. Besides that, customer trust also has a significant effect on repurchase intention and word of mouth. These findings are expected to be an empirical reference regarding the role of overall e-service quality on online consumer behavior. In addition, the results of this study are expected to be an evaluation material for online stores that sell products through Shopee, especially to increase revenue through an electronic service quality-based strategy.

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Overall E-Service Quality, Customer Satisfaction, Customer Trust, Repurchase Intention, Word of Mouth, Site Revisit

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INFLUENCE OF WEIGHTLIFTING ON BLOOD SUGAR AND LIPID PROFILE IN MEN

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As the globe experiences a social media revolution, it is evident that platforms like Facebook, Twitter, Instagram, Snap Chat, Skype, etc., are heavily used for communication. The online exchange of knowledge and information among various groups of people is one of the most significant benefits of using social media. The increase in communication skills among people, particularly among students and learners in educational institutions, is supported by this online information sharing. In addition to mediating communication in various ways, online tools and technology are also changing the way we interact and even how we think about and discuss it. The influence of social media has given rise to a new type of communication where information can be easily shared and dialogues are brief. Due to the wide-ranging effects of social media, companies are looking for experts to fill crucial positions within their organizations. In fact, the use of social media in business is expanding quickly and offers a variety of job prospects. Social media has the power to significantly alter both the interpersonal and collective nature of our social lives.

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Social media, Communication, Marketing, Social media tools.

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A serious psychiatric condition called obsessive-compulsive disorder (OCD) affects about 2% of both children and adults in society. OCD has been linked to families in studies of family aggregation, and findings from twin studies show that this relationship is partially influenced by genetic factors. Only three genome-wide linkage studies have been finished so far, and the findings are merely suggestive. More than 80 candidate gene studies have also been released. These studies have mainly concentrated on genes in the dopaminergic and serotonergic pathways. Unfortunately, none have been replicated and, with the exception of the glutamate transporter gene, none have reached genome-wide significance. In order to obtain sufficiently large samples of people with OCD, use cutting-edge laboratory techniques, and carry out the bioinformatic analyses necessary to identify risk loci, multidisciplinary teams of investigators will need to collaborate in future studies. Steroids may be influencing how the disorder develops, according to some theories. However, only a few studies have examined hormone levels and obsessive-compulsive (OC) symptoms simultaneously to date; as a result, there is little direct proof of this association. As a result, more thorough research into neurotransmission in OC patients has linked OCD pathology to the serotonergic, dopaminergic, and glutamatergic neurotransmitter systems. The molecular and cellular mechanisms underlying the pathogenesis of "obsessive-compulsive disorder-like" behaviors have started to come into focus in recent studies of novel mouse genetic models with excessive grooming behaviors Hoxb8, Sapap3, and Slitrk5 are three genes that are genetically deleted in mice, resulting in pathological behaviors such as adult-onset excessive grooming with mild to severe hair loss and self-injury. The abnormal grooming behaviors are linked to increased anxiety in two of the models, the Sapap3-deficient and the Slitrk5-deficient mice, and these pathological behaviors can be reduced with subchronic administration of a selective serotonin reuptake inhibitor, indicating the predictive validity of such models. These models' molecular, pathophysiological, and genetic analyses offer several new insights into the causes of these mice's abnormal behaviors. In this review, we are going to focus on understanding these genetic and hormonal influences in triggering OCD.

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Obsessive-Compulsive Disorder, Molecular Mechanism, Genetic Factors, Hormonal Factors

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Langmuir model, Adsorption, Rare earth elements

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??? ?????? ?? ?? ?? ??????? ? ????? ???????? ???? ?? ?????? ?????? ??????????? ????? ??? ?????????? ?????? ???? ??? ?? ?? ?? ??????? ?? ?????? ?? ???? ???? ???????? ?? ???? ???? ??????? ???? ???? ?? ????? ?? ??????, ?????????? ? ??????? ?? ????? ???? ??? ????? ???? ?? 565 ?? ???? ???? ???????? ?? ???? ??? ?????? ???? ???? ?? ??????? ????? ????? ???? ?????? ???? ?? ???????? ?? ?? ????? ????????? ??????? ?? ???????? ?? ?? ??? ?? ?? ??????? ? ?? ????? ???? ???? ???? ?? ?????? ??????? ?? ??????, ?????? ?? ????????? ?????? ?? ???? ?? ???, ???? ?? ?? ??????? ????????- ?????? ????????????? ??????? ?? ??? ??? ???? ????? ???????? ?? ??????? ?????? ?? ???????? ?????, ????? ?????????? ??????? ???? ?? ?????? ?? ??????????, ????????? ?? ???? ?? ???? ??????? ????? ?? ??? ??? ?? ?? ??? ??????? ?? ????? ?? ??????? ?? ???? ????????? ???? ???? ?????? ?????? ?? ??? ???? ?????? ???? ?????? ??????? ?? ???????, ????????? ?? ?????????? ???? ???? ?? ??? ???? ??? ??????? ??????? ??? ?? ?? ?? ??????? ? ????? ???? ?? ??????: ?????? ?????? ?????? ???? ????

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????? ????: ????????, ??????, ???????, ?????? ???? ?? ????????

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This thesis compares Digital Advertising versus the conventional methods of Advertising. The Digital advertising is the future method and most effective tool in filed of Marketing and Advertising.

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Digital Marketing (Journalism)

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To Kill a Mockingbird is a modern American classic that presents, among other issues, an important family concern i.e. how to rear up children in a particular way so as to make them independent and responsible citizens. It has almost assumed the status of a father's manual guide to teach him the methods of socialization. The novel is more than just a book in children literature. Scout is the protagonist/narrative voice of the novel, which has attracted the attention of readers for her manner and sophistication. There is ample textual evidence of gender sensitive issues in upbringing of Scout taken up by her father that indicates that the protagonist's trajectory from naivety to maturity in this bildungsroman happens through his mentoring. The role of her father and other people in the environment seems very significant in constructing Scout's self-esteem and identity. She is groomed under Atticus's parenting style, attachment style, and his personality. This is what is duly focused on in this research paper. Harper Lee successfully manages objectivity in dealing with serious issues of racism and Southern social attitudes, along with questions of good and evil, caste division and class distinction, education of children, gender socialization, and the development of an individual's /daughter's conscience.

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Father, gender, education, socialization, parenting style, attachment patterns, social attitudes.

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